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Anatomy
The study of the structure and physical parts of an organism.
Physiology
The study of how an organism and its body parts function.
Evolution of body plans
Structural traits (anatomy) and functional traits (physiology) evolve together.
Form and function
The shape and structure of a body part are related to the job it performs.
Architectural constraints
Existing body structures limit how new structures can evolve.
Four-limbed body plan
The ancestors of modern land vertebrates had four limbs; bird and bat wings evolved through modifications of existing forelimbs.
Homeostasis
The maintenance of a relatively stable internal environment within an organism.
Sensory receptor
A structure that responds to a specific stimulus, such as temperature or light.
Stimulus
A change in the internal or external environment that triggers a response.
Negative feedback mechanism
A process in which a change causes a response that reverses or counteracts the original change.
Thermoregulation
The regulation of body temperature through processes that produce, conserve, or release heat
Hypothalamus
A region of the brain that acts as the body's temperature-regulating control center
Set point
The target value that the body attempts to maintain, such as its normal core temperature.
Sweating
A cooling response that releases sweat onto the skin; evaporation removes heat.
Shivering
Involuntary muscle contractions that generate heat when the body is cold.
Metabolic heat
Heat generated by the body's chemical reactions and energy use
Thermoneutral environment
An environment in which the body does not need to expend additional energy to maintain its core temperature.
Heat dissipation
The release of heat from the body into the surrounding environment.
Totipotent
Having the potential to develop into all possible cell types and give rise to an entire organism
Regeneration
The ability to replace or regrow body parts or tissues lost through injury.
Invertebrates
Animals without backbones; some have a particularly strong ability to regenerate body parts.
Sea star regeneration
Some sea stars can regrow an entire body from one arm and a portion of the central disk
Stem cells
Undifferentiated cells that can divide and develop into specialized cell types.
Stem-cell potency
The number of different cell types or developmental fates a stem cell can become.
Pluripotent
Able to develop into many different cell types in the body.
Unipotent
Able to develop into only one specific cell type.
Embryonic stem cells
Pluripotent cells that can develop into many types of cells in the human body.
Induced pluripotent stem cells (iPSCs)
Stem cells created in a laboratory that function similarly to embryonic stem cells.
Specialized stem-cell populations
More restricted stem cells that continually replace certain tissues, such as skin and blood.
Cell differentiation
The process through which a cell develops specialized structures and functions.