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Chapters 4, 12, 13 & 14
Viruses charactersitics
contains DNA or RNA; have protein coat; must have a host cell; uses metabolic machinery of host
host range
specific viruses have requirements for attachment and the availability of cellular factors in a host for viral multiplication
how do viruses infect?
they must chemically interact with the receptor on the cell
oncolytic virsuses
selectively infect and kill tumor cells; form of cancer imunotherapy
phage therapy
use of viruses to treat bacterial infections
how to see viruses
through electron microscopy
capsid
protein coat that protects the nucleic acid
envelope
an additional layer to the capsid that is a combination of lipids, proteins, and carbs; in some but not all virsues
spikes
carbs projecting from the surface; may or may not cover the envelope
viruses nucleic acids
DNA or RNA (not both)
hemagglutination
the clumping or agglutination of red blood cells
coagulation
the formation of a solid, insoluble mesh of fibrin, platelets, and rbcs
helical viruses
long rods within a cylindrical capsid that has a helical structure
polyhedral viruses
many-sided
icosahedron
a category of polyhedral viruses and have 20 triangular faces and 12 corners
enveloped viruses
roughly spherical enclosed by an envelope
complex viruses
especially bacterial viruses and have other attachments to the capsid