CH 17 5 Antibody Classes

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5 Terms

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IgM

  • Pentamer

  • First antibody produced

  • Can bind 10 antigens

  • Agglutination

  • Activates complement

Memory:
👉 M = Made first

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IgG ⭐


  • Next.. comes in and cleans up

  • Monomer

  • Most common in blood

  • Long-term immunity

  • Crosses placenta

  • Protects fetus/newborn

  • Neutralizes toxins/viruses

  • Helps phagocytosis

  • Activates complement

Memory:
👉 G = Goes through placenta


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IgA

  • Monometer Or Dimer

  • Found in secretions

  • Breast milk

  • Mucous membranes

  • Protects respiratory/GI surfaces, mucous membrane

Memory:
👉 A = Areas with mucus


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IgE

  • Monomer

  • Allergic reactions

  • Binds mast cells + basophils

  • Helps fight parasitic worms

Memory:
👉 E = Everything itchy/allergies.. EVIL Antigen 

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IgD


  • On naïve B cells

  • Monomer- CAN BIND 2 ANTIGENS

  • Helps act as a B-cell antigen receptor

  • Rare in blood