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functions of spinal cord
conduction, neural integration, locomotion, reflexes
conduction
nerve fibers conduct sensory and motor information up and down the spinal cord
neural integration
spinal neurons receive input from multiple sources, integrate it, and execute appropriate output (e.g., bladder control)
Locomotion
spinal cord contains central pattern generators: groups of neurons that coordinate repetitive sequences of contractions for walking
refelxes
involuntary, responses to stimuli
- vital to posture, coordination, and protection
spinal cord
cylinder of nervous tissue that arises from the brainstem at the foramen magnum of the skull
segment
part of the spinal cord supplied by each pair of spinal nerves
cervical enlargement
nerves to upper limb
lumbar enlargement
nerves to pelvic region and lower limbs
medullary cone
cord tapers to a point inferior to lumbar enlargement
cauda equina
bundle of nerve roots that occupy the vertebral canal from L2 to S5
meninges
three fibrous membranes that enclose the brain and spinal cord
dura matter
surrounds spinal cord and is separated from vertebrae by epidural space
arachnoid matter
adheres to dura and is seperated from pia by fibers spanning the subarachnoid space that is filled with cerebral spinal fluid
pia matter
delicate membrane that follows contours of spinal cord and continues inferiorly as fibrous terminal filum that fuses with dura to coccygeal ligament
gray matter
neuron cell bodies, dendrites, and unmyelinated axons
- site of info processing and synaptic integration
white matter
abundantly myelinated axons
Carry signals from one part of the CNS to another
gray commissure
connects right and left sides
- has central canal lined with ependymal cells filled with CSF
lateral horn (gray matter)
contains neurons of sympathetic nervous system
columns/funiculi (white matter)
three pairs of these white matter bundles
- posterior, lateral, anterior on each side
-tracts/ fasciculi divsions of each column
ascending tracts
carry sensory info up
descending tracts
carry motor info down
Decussation
crossing in the midline that occurs in many tracts so that brain senses and controls contralateral side of the body
contralateral
when the origin and destination of a tract are on opposite sides of the body
ipsilateral
when the orgin and destination of a tract are on the same side of the body and does not decussate
sensory signals travel across ___
3 neurons
- first order: detect stimulus and transmit signal to spinal cord or brainstem
- second order: continues to the thalamus at the upper end of the brainstem
- third order: carries the signal the rest of the way to sensory region of cerebral cortex
descending tracts involve ____
2 motor neurons
- upper motor neuron: starts in cerebral cortex or brainstem and terminates on lower motor neuron
- lower motor neuron: nuerosoma is in brainstem and spinal cord
Corticospinal Tracts
carry signals from cerebral cortex for precise fine movement
pyramids
ridges on anterior surface of medulla formed from fibers of this system
- most fibers decussate in lower medulla
nerve
cord like organ composed of numerous nerve fibers bound together by connective tissue
nerve fibers in PNS
surrounded by Schwann cells that form neurilemma and myelin sheath around axon
endoneurium
loose connective tissue external to neurilemma
perineurium
layers of overlaping squamous cels that wrap fascicles: bundle of nerve fibers
epineurium
dense irregular connective tissue that wraps entire nerve
sensory afferent nerves
carry signals from sensory receptors to the CNS
motor efferent nerves
carry signals from cns to muscles and glands
mixed nerves
consist of both afferent and efferent fibers
ganglion
cluster of neurosomas outside the CNS
- enveloped in an endoneurium continuous with that of the nerve
31 pairs of spinal nerves
8 cervical
12 thoracic
5 lumbar
5 sacral
1 coccygeal
posterior branch
dorsal
root is sensory input to spinal cord
Posterior root ganglion
contains the neurosomas of sensory neurons carrying signals to spinal cord
anterior ventral root
is motor output out of spinal cord
anterior ramus
In thoracic region, it gives rise to intercostal nerve
In other regions, anterior rami form plexuses
posterior ramus
innervates the muscles and joints in that region of the spine and the skin of the back
menigeal branch
reenter the vertebral canal and innervates the meninges vertebrae and spinal ligaments
Cervical Plexus (C1-C5)
supplies neck and phrenic nerve to the diaphragm
Brachial Plexus (C5-T1)
supplies upper limb and some of shoulder and neck
median nerve
carpal tunnel syndrome
Lumbar Plexus (L1-L4)
Supplies abdominal wall, anterior thigh, and genitalia
Sacral Plexus (L4-S4)
supply lower limbs, sciatic nerve: lower limb
coccygeal plexus (S4-Co1)
supplies a small area of skin in coccygeal region
somatosensory function
carry sensory signals from bones joints muscles and skin
proprioception
brain receives info about body position and movements from nerve endings in muscles tendons and joints
Dermatome
a specific area of skin that conveys sensory input to a spinal nerve
dermatome map
a diagram of the cutaneous regions innervated by each spinal nerve
dermatones are need to
anesthetize 3 successive spinal nerves to produce a total loss of sensation in one dermatome