PPP Beta, alpha, and muscainic receptors

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7 Terms

1
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α-1

NE binds to α-1 = vasoconstriction (high BP) Gq: increases Ca2+ release

2
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α-2

binds to epinephrine or norepinephrine and inhibits to reduce sympathetic activity (Gi)

3
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β-1

binds to NE and E which then increases HR (positive chronotropic) and contraction (positive ionotropic)

4
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β-2

β-2 binds to E = vasodilation

5
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μ-1

Gq pathway increases Ca2+ signaling (neuronal activity and gastric acid secretion)

6
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μ-2

Slows heart rate by binding to ACh and decreasing cAMP

7
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μ-3

vasoconstriction, exception (NO created in vascular endothelium = vasodilation)