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zygote
the single cell formed by fertilization of an oocyte by a sperm
week 8
the embryonic period of development ends at the end of
dorsal
in which side of the embryo does the spinal column develop?
the second meiotic division
immediately after entry of the sperm head into the cytoplasm of the oocyte, the oocyte completes
increase the number of cells but not the size of the embryo
the cleavage divsions producing the morula
inner cell mass
in the blastocyst, the embryo develops from the
bilaminar disc
after implantation, the embryo develops as a
syncytiotrophoblast
human chorionic gonadotropin (HCG) is produced by the
epiblast
the floor of the amniotic cavity is formed by the
trilaminar disc
gastrulation is the process that forms the
both the cranial-caudal and left-right axes
the primitive streak determines
notochord
what structure induces the formation of the neural plate?
mesoderm
somites develop from
cranial to the developing forebrain
before formation of the head and tail folds, the primordial heart lies
gut tube
the lateral folds of the embryo roll the endoderm layer of the embryo into a cylinder, forming the
the study of body function
what is a definition of physiology?
the study of disorders of functioning
what is a definition of pathophysiology?
the study of body structure
what is a definition of anatomy?
groups of cells that make up the skin
groups of cells that line the lungs
groups of cells that line the intestinal tract
examples of epithelial tissues
the set of chemical reactions that are carried out in the body
what is metabolism?
the ability to maintain a steady state of functioning despite internal and external changes
what is homeostasis?
nucleic acids
cell membranes contain all of the following except what?
proteins
nucleic acids
phospholipids
cholesterol
the movement of solute molecules from an area of high concentration to low concentration
diffusion is
the movement of water across a semipermeable membrane from an area of low solute concentration to an area of high concentration
osmosis is
alveoli and capillaries
simple squamous epithelium is found in the
loose and fibrous connective tissues
fibroblasts are the main cells found in
serous membranes
membranes that cover organs and surfaces in closed body cavities are
intracellular fluid
most of the body water is contained in the
potassium ion
the principal cation in intracellular fluid is
bicarbonate buffer system
the buffer system most important in regulation of blood pH is the
proteins
blood plasma contains
the percent of blood made up of red blood cells
the hematocrit measures
normoblast
the last stage of red blood cell development that contains a nucleus is the
120 days
the typical lifespan of a red blood cell is
macrophages
damaged red blood cells are removed from the circulation by
lymphocyte
which of the following cell types is NOT a granular leukocyte?
eosinophil
lymphocyte
neutrophil
basophil
the percent of each type of leukocyte
the differential white blood count of the complete blood count (CBC) measures
the response to infection
white blood cells function in
megakaryocytes
platelets are produced by
membrane-bound cytoplasmic cell fragments
platelets are
vitamin K
the vitamin needed to synthesize many blood clotting proteins is
liver
blood clotting proteins are made in the
activation of platelets
blood clotting is most often initiated by
fibrin
blood clots are made mostly of
action of antithrombin proteins
the blood clotting process is normally stopped by
left subclavian vein
lymphatic vessels from the lower body join into the thoracic duct which empties into the
macrophages
bacteria and foreign materials collected in lymph fluid filter through lymph nodes and are phagocytized by
produce red blood cells
which of the following is NOT a function of the spleen in adults?
phagocytize pathogenic bacteria
phagocytize old red blood cells
store and release platelets
t-cell lymphocytes
the thymus is necessary for development of immune competence in
causes the inflammatory response
innate immunity
antibody production
which of the following is NOT part of innate immunity?
phagocytes
barriers
the complement system
antibody production
natural killer cells
adaptive immunity involves all of the following EXCEPT
t-cell response
b-cell response
response to specific antigens
natural killer cells
thymus
maturation of lymphocytes to allow them to distinguish between self and non-self occurs in the
t-cell lymphocytes
cell-mediated immunity is produced by
b-cell lymphocytes
antibodies are produced by
IgG
the most abundant immunoglobulin in blood is
both cell-mediated and antibody-mediated immunity
phagocytosis of foreign antigens, digestion into protein fragments, and “presentation” of the fragments on the cell surface of macrophages and other cellsis the first step in
opsonization
labeling of a foreign antigen by binding with an antibody to target it for phagocytosis is called
two light chains and two heavy chains
immunoglobulin monomers (like IgG) consist of
activating memory cells leading to large amounts of antibody production
a vaccine booster shot increases immunity to a disease by
hormones
endocrine glands secrete
the bloodstream
unlike other glands, endocrine glands secrete directly into
all of these
endocrine hormones are
proteins and peptides
biogenic amines
steroids
negative feedback mechanisms
hormone levels are controlled by
pituitary gland
the secretion of many endocrine glands is controlled by the
hypothalamus
hormones released by the posterior pituitary gland are synthesized in the
increase water reabsorption
secretion of antidiuretic hormone (ADH) by the posterior pituitary gland causes the kidney to
hypothalamus
secretion of anterior pituitary gland hormones is controlled by releasing hormones synthesized in the
GH (growth hormone)
anterior pituitary hormone that acts directly on tissues rather than by stimulating other endocrine glands is
thyroxine (T4)
iodine is needed to synthesize
low blood calcium (hypocalcemia)
parathyroid hormone is secreted in response to
beta cells of the pancreatic islets
insulin is made in the
gluoneogenesis
glucagon stimulates
epinephrine and norepinephrine
the adrenal medulla secretes
secretion of ACTH by the pituitary gland
cortisol levels are directly regulated by
endoderm
the lining of the pulmonary tree is derived from the
tracheoesophageal folds
the respiratory tract is partitioned from the foregut by growth of the
all of these
normal lung development requires
fetal breathing movements
adequate thoracic space for lung growth
adequate amniotic fluid volume
bronchioles
all of the following parts of the upper respiratory tree contain cartilage EXCEPT
bronchioles
larynx
trachea
bronchi
all of these
the pleural membranes
secrete fluid to prevent friction
cover the outside of the lungs
line the inside of the chest wall
squamous epithelium
most of the alveolar wall is made up of
pulmonary surfactant
alveolar collapse due to surface tension is prevented by
is less than atmospheric pressure
intrapleural pressure
all of these
during inspiration (inhalation)
the intrapulmonic pressure falls below atmospheric pressure
the intercostal muscles move the ribs upward and outward
the diaphragm contracts and moves downward
is a passive recoil process
expiration (exhalation)
the volume of air moved in one normal inhalation and exhalation
the tidal volume is
the pressure oxygen gas exerts in a mixture of gases
the partial pressure of oxygen (PO2) is
differences in partial pressures across the membrane
diffusion of O2 and CO2 across membranes is driven by
all of these
the oxygen saturation of hemoglobin (SaO2) is
related to the pO2
higher in arterial blood than in venous blood
the percent of hemoglobin that is oxygenated
bicarbonate
transport of carbon dioxide in the blood is mainly in the form of
endoderm
most of the gut is derived from
foregut
the liver is a derivative of the
umbilical cord
rotation of the midgut occurs while the small intestines are contained in the
starch
saliva contains the digestive enzyme amylase which breaks down
lower esophageal sphincter
gastroesophageal reflux (GERD) is cuased by dysfunction of the
mucosa
in the stomach and intestine, digestive enzymes are secreted by the
parietal cells
in the stomach, HCl is produced by the
vitamin B12
intrinsic factor is secreted by the parietal cells of the stomach and is needed for abrosption of
small intestine
the process of digestion is completed in the
bile salts
the liver participates in digestion by production of