Pharma 2 lab(mid)

Interferes with metabolism great efficacy vs nematodes recommended for repeated

BENZIMIDAZOLE

inhibition of acetylcholinesterase of parasites

ORGANOPHOSPHATES

A pro drug under BENZIMIDAZOLE

Febantel probenzimidazole(prodrug)

ORGANOPHOSPHATES is contraindicated in_____(+) dogs

CHW

cthat has cholinergic agonist

TETRAHYDROPYRIMIDINES

TETRAHYDROPYRIMIDINES examples?

pyrantel embonate, pamoate, tartrate

Antinematodals stimulates cholinergic nervous system

IMIDAZOTHIAZOLES

used as microfilaricide and has anti-inflammatory and immunostimulant properties

IMIDAZOTHIAZOLES

IMIDAZOTHIAZOLES examples?

Levamisole

blocks neuromuscular transmission

PIPERAZINE COMPOUNDS

bind to Cl- channels in invertebrate nerve and mm cells

VERMECTINS

Anticestodal that increases permeability of cell membrane

PYRAZINE DERIVATIVE

They are effective vs all cestodes

Praziquantel

effective vs Dipyllidium and Taenia

Epsiprantel

anti trematodals that inhibits trematode enzymes for energy production

CLORSULON

effective vs mature and immature Fasciola hepatica

benzene sulfonamide

effective vs adult Fasciola hepatica

ALBENDAZOLE

interferes with energy metabolism

ALBENDAZOLE

they are effective vs lung trematodes of cats and dogs

PRAZIQUANTEL and TRICLABENDAZOLE

Dirofilaria immitis(nematode) is transmitted by ________

mosquitoes

Drug that kills adult heartworms

melarsomine

melarsomine are arsenic based and given via?

deep IM

prevents development to adults of heartworms

Ivermectin

Heart worm patients need how many DOXY?

10mg/kg BID 4 weeks

Heart worm patients need how many Prednisone?

0.5mg/kg taper accordingly for 4 weeks CHW

preventive: every 30 days

Heartworm patients need how many Melarsomine

2.5mg/kg IM D61, 90, and 91

INSECT GROWTH REGULATORS

methoprene

CHITIN SYNTHESIS INHIBITORS

Lufenuron

binds and inhibits nicotinic Ach

nitenpyram

increases efficacy of pyrethrins and pyrethroids

piperonyl butoxide

insect neurotoxin

IMIDACLOPRID

has residual effects even after bathing

Fipronil

causes involuntary muscle contractions

fast and long acting

administer with food

Spinosad

blocks Na influx

Causes hypersalivation if licked

Metaflumizone

stimulates excess adrenergic activity in parasite NS

Amitraz

antimicrobial, antiparasitic ECTOPARASITE

Sulfurated lime

Repellants for ectoparasites

butoxypolypropylene glycol

citrus peel extract

some insecticidal activities

quick kill

pleasant smell

d-limonene

They are organophosphates cholinesterase inhibitors

malathion

fenthion

dichlorvos

They are Carbamates cholinesterase inhibitors

carbaryl (cats and dog)

propoxur (cats and dog)

Bendiocab (large animals)

GABA Cl channel inhibitor ectoparasite

afoxolaner

Sarolaner

fluralaner

for Candida albicans in the GIT

Nystatin

skin infections and crop mycoses

not absorbed in the GIT

Nystatin

IV or topical

poor tissue penetration

Blastomycosis, Aspergillosis, Coccidiodes, Histoplasmosis, Cryptococcosis

Amphotericin

oral antifungal against systemic mycoses caused by Candida, Aspergillus, Cryptococcus, Histoplasma, Blastomyces, and Malassezia.

Itraconazole

CNS infections

against systemic mycoses caused by Cryptococcus, Blastomyces, Histoplasma, and Malassezia.

Fluconazole

for treatment of Cryptococcus

well absorbed in the GIT

bone marrow depression

Flucytosin

for superficial mycoses

oral formulation

or infections on nail, skin, and hair (ringworm)

Griseofulvi

allylamine antifungal for infections caused by dermatophytes and Malssezia

Terbinafine