DENT 267: LO1 LS2- Gingival Diseases Associated w/ Blood Dyscrasias (Leukemia, Neutropenia)

leukemia associated gingivitis

-malignancy of blood forming tissue

-leukemic cells can infiltrate gingival tissues

-acute (childhood), chronic (adults)

-usually local irritants such as biofilm initiate the oral changes

-immature/abnormal WBC infiltrate gingival CT via blood vessels & stimulate tumour-like enlargement

-stimulates fibroblasts, increases gingival thickness and creates pockets

-may get purplish masses that develop

types of leukemia

-myeloid, lymphoid

-acute, chronic

planning care for leukemia-associated gingivitis

-medical cons regarding blood studies prior to any invasive assessment or treatment

-prophylactic antibiotics may be required

-client education, debridement, correction of biofilm retentive factors

-eval

-prevention

-frequent maintenance

leukopenia

-large group of disorders that affect the cellular elements of the blood

gingival diseases associated w/ blood dyscrasias

-aplastic anemia, agranulocytosis, cyclic neutropenia, various forms of leukemia

planning care for gingival diseases associated w/ blood dyscrasias

-cons w/ the client's physician to determine risk of infection

-premed w/ antibiotics prior to invasive treatment if WBC low

-consult physician re type of premed

-proceed w/ perio therapy, regular maintenance intervals when cleared

-may be dealing w/ undiagnosed systemic disease

-oral signs may be the first of the disease

what should we do if we suspect a systemic disease or the clinical signs are more than one would expect for the amount of biofilm and/or deposit

-medical consult