1/84
Looks like no tags are added yet.
Delirium and dementia similarities
Confusion/disorientation, impaired memory and attention span, anxiety and agitation, sundowning
Neurocognitive disorder
Previously known as Dementia
Sundowning
Increased confusing towards the end of the evening
Delirium risk factors
-Can be advanced age
-metabolic (kidney or liver failure)
-fluid/electrolyte imbalance
-cardiovascular disease/ respiratory disease
-*infection
-surgery
-substance use/withdrawal
-polypharmacy
-ICU (loses track of time)
-*males greater risk than females
Dementia risk factors
-advanced age
-prior head traumas
-cardiovascular disease/respiratory disease
-lifestyle factors (risky behaviors, drug use, no helmet)
-family history
Delirium
Disruption of thinking, memory, processing, and problem solving. Needs to be treated promptly (medical emergency), treatable. "Where THE F AM I"
Goal with delirium
Find out what the underlying issue is, treat it, and patient will be fine
Delirium key clinical features: where
Disorientated: check A&O x4 for severity, as severity progresses it goes in descending order- why are you at the hospital? What time? Where are you? Who are you? (Most severe)
Delirium key clinical features: thought disorganization
Non sensical statements, responds to commands that don't make sense, severe forms speech and language can be lost entirely. Cannot process things- asked to sign papers but responds by getting up and clapping
Delirium key clinical features: hallucinations
Majority are visual, patients appear to be responding to internal stimuli. Energy changes.
Delirium hyper active energy change
Restless babbling agitation, worse at night (sleep wake cycle reversed)
Delirium hypo activity energy changes
Slow sleepy low energy
Delirium Sleep wake cycle energy changes
Reversed, sleep during the day awake during the night
If a patient cannot sleep what interventions can we provide
Read a book, color, puzzle, relaxing non stimulating activities
Delirium key clinical features: fluctuating
Patient will appear to be cognitive during the morning and then in the afternoon have confusion and hallucinations, sundowning, acute: rapid onset, span of a few hours or days, can recover from rapidly if the underlying cause is treated, if prolonged illness s/s of delirium can persist longer
Fluctuating can be diagnostic in some causes because
In Dementia the confusion can be more consistent and enduring, Delirium cycles more rapidly within 24 hours, dementia cycles longer usually within a week
Medical causes/ intoxicants for delirium
PINCH ME: poorly controlled pain, infections (ie UTI), nutrition (ie poor diet and vitamin deficiency), constipation (common under-recognized trigger), hydration (dehydration), medications (can be prescribed or illicit drugs can trigger), endocrine (diabetes, thyroid disorder)
Treatment for delirium
Treat the underlying cause, re-orientation, promote sleep, antipsychotics and or antianxiety, curable
Dementia
Progressive neurodegenerative disease, cognitive decline that impairs daily functioning, permanent no cure
Types of dementia
Alzheimer's (70% of cases)
Vascular dementia (15%)
Dementia with Lewy bodies
Frontotemporal dementia (second most common)
Risk factors for dementia
Age is largest risk factor -age 65 has 2% prevalence age 85 has 40% prevalence, genetics, gender- females>males due to women living longer
Dementia s/s progressively
Get worse over time
Pre dementia S/S
Up to 10 years before clinical symptoms, mild symptoms: forgetfulness, poor orientation, changes in mood, struggling to find the right words, anosmia (loss of smell)
Early dementia s/s
Difficulties with- coming up with the right words or names, remembering names, forgetting material just read, losing objects or items, experiencing trouble planning
Middles dementia s/s
Increase difficulty with- forgetting personal history, feeling moody or withdrawn, unable to recall address phone number high school or college they attended, requiring help with choosing proper clothing, bladder control, sleep patterns, increased tendency to wander or get lost, increase paranoia, can have OCD type behaviors
Late dementia s/s
May require- round the clock care with ADLs, loss of awareness, difficulty communicating, vulnerable to infections especially pneumonia due to lying down a lot and sedentary lifestyle
Mild stage of dementia example
Frequently forgetting the little things "did I have an MD appointment today? Did I take my meds this morning? Where did I park my car?"
What are the safety concerns with mild stage of dementia
Not taking medications, doubling up on medication
Moderate stage of dementia example
"Have we met before? I'm lost and need to get home, wait are you sure I own a car?"
What are the safety concerns with moderate stage of dementia
Stranger danger, not able to recognize known people or safe people
Severe stage of dementia example
Client may have now forgotten how to talk walk swallow or perhaps even breathe
What are the safety concerns for severe stages of dementia
Aspiration
The 4 As of dementia (Alzheimer's)
Amnesia (loss of Memory), apraxia (the loss of ability to execute or carry out skilled movement and gestures, despite having the physical ability and desire to perform them), agnosia (loss of ability to identify people or objects), aphasia (loss of ability to swallow)
Choline's erase inhibitors (dementia meds)
Goal is to increase acetylcholine at the neurotransmitter receptor site by stopping acetylcholinesterase from breaking down acetylcholine
Choline's erase inhibitors (dementia meds) names
Donepezil (taken at night w or w/o food)
Rivastigmine, galantamine
Choline's erase inhibitors (dementia meds) adverse effects
GI problems: nausea vomiting and diarrhea (watch for fluid and electrolyte imbalances), may be reduced if titrated
Syncope/bradycardia: screen for orthostatic hypotension and watch for fall risks
Blurred vision, dizziness, and sedation: monitor for falls
Urinary urgency
Choline's erase inhibitors (dementia meds) contraindications
Asthma, COPD (increased acetylcholine can cause Bronchoconstriction)
Choline's erase inhibitors (dementia meds) outcome/goal
Mother ability to perform self care and slow cognitive deterioration in mild to moderate stages
Choline's erase inhibitors (dementia meds) interactions
No NSAIDS (increased risk of GI bleeding)
Choline's erase inhibitors (dementia meds) nursing considerations
-Never discontinue abruptly, taper down, can cause progression of clinical manifestations
-monitor for ability to swallow tablets in the elderly meds can come in a solution except donepezil
-medication to be taken at night before bed to sleep through major side effects
NMDA receptor antagonist (dementia meds)
Memantine, when glutamine levels rise in the brain it causes increase levels of calcium which can damage nerve cells, binds to the NMDA receptors and prevent binding
Of glutamate preventing the release of calcium
NMDA receptor antagonist (dementia meds) adverse effects
GI problems: nausea vomiting diarrhea constipation
NMDA receptor antagonist (dementia meds) contraindications
Pregnancy/breast feeding, epilepsy/ seizure disorder, severe hepatic and renal impairment
You are discharging an elderly client with moderate Alzheimer's disease what are some home safety measures you can teach the family to best keep the client free from accidental injuries
Toddler proof the house, add an additional lock to front door either higher up or down low, add rails along hallways stairs and in bathroom, label cabinets, remove rugs/electrical cords/ clutter, place bed mattress on the floor, remove stove nobs, set water heater at 95 degrees
Addiction
A disease of the pleasure pathways in the brain that also destroys all other pleasure pathways
Intoxication
Specific to the individual when the person has consumed excessive amounts for themselves
Tolerance
Needing more of the substance to achieve the desired effect, amount needed to feel physical effects
withdrawal
Typically begins 8 hours after last use the body experiences adverse effects as the chemical leaves the system
DSM-V criteria for substance use disorder
Loss of control (might want to quit but can't), large amounts of time spent on acquiring the drug using the drug or recovering from excessive use of the drug, negative impact on role responsibilities, displaces tolerance and withdrawal
Addictive substances
Alcohol, amphetamines, benzos, cocaine, opioids, caffeine, cannabis, hallucinogens, inhalants, tobacco
Uppers (stimulants)
Increase vitals mental activity and physical activity
Downers (depressants)
Decrease vitals mental activity and physical activity
If the drug causes increased vitals mental activity and physical activity what will occur with withdrawal
Withdrawal will cause decreased vitals mental activity and physical activity
If the drug causes decreased vitals mental activity and physical activity what will occur with withdrawal
Withdrawal will cause increased vitals mental activity and physical activity
Opioid pupillary response
Constructed during intoxication dilated during withdrawal
Opioids
Downer, attaches to CNS receptors to alter response to pain and causes CNS depression
Opioids examples
Heroin, morphine, hydromorphone, can be smoked inhaled or swallowed, causes pain relief and euphoria
Opioids intoxication
Slurred speech, decreased respirations, decreased LOC, antidote is naloxone
Opioids withdrawal
Sweating, irritability, weakness, diarrhea, pupil dilation, nausea, vomiting
What are patients at risk for during opioid withdrawal
Developing delirium
Alcohol/ cannabis
CNS depressant
Cannabis intended effects
Euphoria, sedation, can have hallucinations only in high doses, pain relief
Alcohol intended effects
Relaxation decreased social anxiety decreased stress
Sedatives/hypnotics/anxiolytics
Benzodiazepines, barbiturates, club drug (flunitrazepam)
Benziodiazepines antidote
Flumazenil (ROMAZICON)
What are patients at risk for with benzodiazepine withdrawal
Seizures
Barbiturates
Phenobarbital, no antidote
Club Drug
Flunitrazepam (roofies)
Alcohol use disorder cage questionnaire: C
Cut: do you ever feel like you should cut down on your drinking
Alcohol use disorder cage questionnaire: A
Annoy: do you ever get annoyed when people criticize your drinking
Alcohol use disorder cage questionnaire: G
Guilty: do you feel guilty about your drinking habits
Alcohol use disorder cage questionnaire: E
Eye opener: do you ever need a drink/eye opener first thing in the morning to get your day started
What are patients at risk for when withdrawing from alcohol
Seizures
Rules of engagement for med surge vs mental health with alcohol use disorder
All side rails up is a no go in med surge but yes is mental health for patient safety
Alcohol use treatment: withdrawal
Diazepam- agitation
Carbamazepine- seizures
Clonidine- blood pressure because stress/anxiety increases BP
Chlordiazepoxide- anxiety/agitation
Phenobarbital- anti seizure/sedative
Naltrexone- suppresses opioid cravings
Withdrawal can cause a decrease in thiamine which can cause brain swelling, treatment is vitamin B12
Alcohol use treatment: abstinence
Disulfram- deters alcohol use by causing unpleasant reactions (monitor for fluid/electrolyte imbalances)
Naltrexone- reduces cravings for alcohol and opioids
Acamprosate- supports abstinence in alcohol use disorder
Cocaine
CNS stimulant, rush of euphoria and pleasure and increased energy
Cocaine toxicity
-Hallucinations, seizures, extreme fever
-Cardiovascular collapse and death
Amphetamines/methamphetamines
Amphetamines rich people, methamphetamines poor people, causes rush of euphoria and pleasure increased activity, can cause extreme agitation irritability and hypervigilance
If a patient has a history of meth use what should the nurse do
Skin checks
Inhalants
CNS stimulant, amyloid nitrate, nitrous oxide, solvents used by kids, causes euphoria
Inhalants toxicity
Slurred speech stupor coma and respiratory depression
Inhalants withdrawal effects
None
Hallucinogens
CNS stimulant, LSD, Peyote, PCP, causes heightened sense of self and altered perceptions such as colors taste smell and feel and causes hallucinations
Hallucinogens withdrawal
Hallucinogen persisting perception disorder- causes visual disturbances and hallucinations that can last intermittently for years