ZOOL-1073 Module 3 Stress and Disease

stress

state of real or perceived disrution to homeostasis

types of stress

eustress, distress

eustress (good/bad)

good

eusrtess

motivates, energizes

eustress eg

exercising, sleeping, laugign

distress (good/bad)

bad

distress

etiologies w potentioal for tissue dimage

distress ex

genetic, congenital, quired

distress may cause or worsen disease

what causes stress

stressor

stressor

any stim that produces stress response

types of stressors

chemical, physical, sychological

endogenous ex of cheical stressor

change in blood chem.,

change in NT and hormon levels,

inflamation and infection

Exogenous ex of chemical stressors

change in O2/CO2 level,

pollutants,

microbes

Endogenous ex of physical stressor

change in BP, CO, BV

change in ventilation, wirhgt, mobility

Exogenous ex of physical stress

change in air pressure,

physcal traume,

noise/light pollution,

work hazards

endogenous ex of Psychological stressor

pain, fear, anxiety, loneliness

exogenous ex of psychological stressor

relas, work, school, social media

dont need to know review section

not tested

areas that interact to manage acute stess, but chronis stres has neg. effect on thek

hypothlamus, preforontal cortex, limbic system, RAD

Ex of how organs that in teract to manage acute stress are neg. afected by chronic stress

stress response AKA

general adaption syndrome (GAS)

GAS under

hypothalamuc conrol

GAS occurs in 3 stages

alarm reaction, stage of resistance, stage of exhaustion

alar rection

immediate neruroendocrine response to stress

alarm reactin AKA

flight or flight

Alarm reaction elvoled for suvival in what way

alarm reaction purpose

quickly mobailze resources for immidiate physical activity

alarm reaction proecss

immediate SNS activate, hypothalamus, NE + some Epi, all ody systems vital to survival mobalized, increase BG

alarm reaction function

delivers glucose and oxygen to organs

HOrmones what activate fight or flight

NE, E

Aldosterone in alarm reaction

decrease kidney blood blow, kidney responds secrete renin,

fight or flight manifestations

dry mouth, cold hands and feet, pallor, shivering, rapid pulse, irregular breathing, headache, angina, transient ischemic attacks, dialated pupils, stomach upstet, indigestion, lack of appetite

activation of fight or flight can feel more stress due to bright lights (T/F)

T

moderate chrnic impbalance, body (is/isn't) adaptive to stress

is

moderate chronic imbalance compensatory mechanisms

allostasus or allostatic load

Moderate chronic imbalance clinical mefestations are subtle

ressistance reaction

adaptation AKA

allostasis

adaptation types

structural, functional, sychological

ex structural adaptation

msucle hypertophy o atriphy

Ex funfctiona apactation

hypersecretion of cortisol

ex psychological adaptation

learned hebaviour

ex internal factors impacting allostasis

genetic predisposition, age, sex

Ex extenal factors impacting allostasis

exposrire to env agetsm life expericen,diatary facts, scocioeconomiv factors

cortisol in resitance reponse

stim protein catabolism, lupolysis, gluconeogenesis

CRH short for...

corticotropin releasing hormone

resisteance reaction

GHRH

growth hormone releasing hormone

GHRH funciton

stim

TRH

thyrotropin releasing hormone

Thyroid function iin ressitance reaction

hypothalamic NR calls secreter TRH diring prolonged stress

TRH hormone

resistanceraction begins mins after alarm reaction

reistantance reaction can last for

exaustion stage

last slide for midterm

exaustion stage