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Testosterone Systemic Effects? (Reproductive system)
Fetal: external/internal genitalia development, descent of testes through inguinal canal into scrotum
Puberty: growth of penis, testes, prostate; promotes spermatogenesis; libido
Testosterone Systemic Effects? (Integumentary system)
Hair growth (pubic, axillary, face, chest, back)
increased sebum production by sebaceous gland (can contribute to acne)
Testosterone Systemic Effects? (Metabolic/muscle)
protein synthesis
↑ metabolic rate (5-10% higher)
↑ skeletal muscle mass
overall anabolic effect
Testosterone Systemic Effects? (Skeletal)
bone growth
↑ bone mineral density (BMD)
eventually epiphyseal closure
Testosterone Systemic Effects? (Hematologic)
erythropoiesis - ↑ production of erythrocytes (red blood cells) by ~20%
Testosterone Systemic Effects? (Renal)
Na+/water reabsorption
Testosterone Systemic Effects? (Vocal cords)
growth and thickening leading to voice deepening