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who discovered cells?
Robert Hooke
How did cells get discovered?
looked at cork under microscope
cell theory
cells are the building block of life, all cells come from preexisting cells, cells are the smallest unit of life that has all life properties, each cell maintains homeostasis
characteristics of life
homeostasis, reproduction, growth, respond to environment, evolution, utilizes energy
2 types of cells
unicellular, multicellular
prokaryotic
no nucleus
eukaryotic
nucleus
similarities between eukaryotes and prokaryotes
DNA, riboses, cytoplasm, plasma membrane, both can be unicellular
prokaryotic differences
~3.5 billion years old, smaller, less structurally complex, no membrane bound organelles, divide by binary fission, bacteria and archaea
eukaryotic differences
evolved from prokaryotic ~2.1 billion years ago, 10-100x larger, more structurally complex, can be multicellular, many membrane bound organelles, divide by mitosis, plants/animals/fungi/protists
what governs the size of cells?
the total metabolic activities of the cell are proportional to the volume of it’s cytoplasm, as cell increase in size the volume of the cytoplasm increases faster than the surface area (making it difficult for enough energy to cross the membrane)
what microscopes can be used to visualize cells?
light, transmission, scanning electron
light microscope
light passes through sample, lens to magnify, magnify up to 1000x (enough to see bacteria)
transmission microscope
electrons bombard thin slice of sample and some pass through, detected with detect electrons and generate a 2D image. can magnify up to 100,000x (can see cellular details)
scanning electron microscope
electrons are used to scan the surface of a sample, produces 3D image
membrane bound organelles
compartmentalize chemical reactions
organelles involved in protein synthesis
nucleus, RER, ribosomes, golgi apparatus, vesicles
factory for lipids and carbs
SER
nucleus function
houses and protects most of the cells DNA
dna purpose
holds the instructions on how to make each protein
DNA function
controls structure and behavior of cell
DNA is packed into ____
chromosomes
how many chromosomes do humans have
46
where is the nucleolus
in middle of nucleus
nucleolus function
make ribosomal RNA
what makes the ribosome
rRNA and protein
what does a ribosome do
synthesis of proteins
nuclear envelope structure
double layer membrane with nuclear pores (“doorways”)
gene
small segment of dna
where are the instructions to make a protein found?
gene
Nucleus role in protein synthesis
convert DNA to mRNA via transcription to carry the instructions into the cytoplasm
ribosome structure
two subunits (large and small), non membraneous
ribosome function
grabs and reads the mRNA instructions to make a protein vis translation
endoplasmic reticulum types
rough, smooth
RER structure
flattened sheets, ribosomes
SER structure
hollow tubes
RER function
protein factory
SER function
carb and lipid factory, Calcium ion storage
golgi apparatus structure
stack of flattened disks, connected via vesicular transport
golgi function
modifies, stores, and distributes proteins. makes lysosomes
vesicle structure
small bubble of membrane
vesicle function
ships and store cellular products
2 types of specialized vesicles
lysosome, peroxisome
peroxisome function
collects toxins and destroys
lysosome function
recycles worn-out organelles/food and send out the remaining product via exocytosis
mitochondria structure
outer membrane, intermembrane, intermembrane space, matrix
matrix
center of inter membrane space
mitochondria function
cellular respiration
cellular respiration
use glucose and other biological molecules to make ATP
organelle involved in support and movement
flagella, cilia, cytoskeleton, centrioles, extracellular matrix
where are flagella and cilia found
plants, animals, fungi, protista
cilia structure
short cellular extensions found in groups, bristle-like
cilia function
move in coordinated sweeping motion to move substances across the surface of the cell
flagella structure
long tail-like cellular extentions
flagella function
moves in propeller like motion to move the cell forward
only cell in humans with flagella
sperm
centrioles structure
short, rode-like structures near the nucleus
centrioles function
cell division, help align and divide genetic material
cytoskeleton structure
located inside cell, network of protein fibers, easily disassembled and reassembled
cytoskeleton function
maintain cell shape, anchors organelles in place, intracellular highways
function of plasma membrane is similar in function to our ______
skin
plasma membrane function
barrier between external and internal environment, sensitivity to the environment, regulates the transport of material into and out of the cell, maintain stable internal environment
plasma membrane structure
phospholipid bilayer, cholesterol, studded with membrane proteins, fluid mosaic
fluid mosaic
proteins can move through the bilayer
phospholipid structure
hydrophilic head, hydrophobic tail
cholesterol function
increases flexibility of the plasma membrane, helps anchor proteins to the plasma membrane
membrane proteins functions
anchoring, identifiers, enzymes, receptors, carrier proteins, channels
types of membrane transport
passive and active
types of passive transport
diffusion through lipid layer, diffusion through channels, osmosis, facilitated diffusion
what types of molecules use diffusion through lipid layer
small, uncharged, lipid-soluble
what types of molecules use diffusion through channels
large, charged, water-soluble proteins
what types of molecules use facilitated diffusion
large, charged, water soluble proteins
what is facilitated diffusion
diffusion across membrane with the aid of a transport protein (similar to a doorway)
what types of molecules use osmosis
water
what is osmosis
net movement of H2O across a selectively permeable membrane with the aid of a protein (because water has partial charges)
when does osmosis occur?
when there’s a membrane that doesn’t allow some solutes through so water will move instead to reach equilibrium
types of tonicity
hyper, hypo, iso
hypertonic
cell place in a more concentrated solution
hypertonic result
water leaves cell, membrane shrinks
hypotonic
cell placed in less concentrated solution
hypotonic result
water enters cell, cell expands and can lyse
isotonic
cell placed in equal concentration solution
isotonic result
no net change
types of active transport
vesicular, pumps
types of vesicular transport
exocytosis, endocytosis
pumps
proteins that have receptor cites for substances
sodium potassium pump
very important for a lot of life functions
how does the sodium potassium pump work?
3 sodium ions and ATP bind to pump, pump changes shape and allows Na through. new shape allows potassium ions to bind. releasing the phosphate group allows the channel to revert to original form and release the potassium
endocytosis
brings substances into the cell
exocytosis
moves substances out of the cell