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Movement skills are stored in memory and can be…
Modified with practice
Degrade when you don’t practice
Be lost with brain damage
Forgotten with dementia
CNS as the driver
The CNS is the driver, the musculoskeletal system is the car
International Anatomical Terminology
anatomical terms used to discuss the human body developed as a universal language
Sagittal Plane
divides into left and right (not always even)
Median/Mid-Sagittal Plane
divides into left and right (two equal parts)
Hands and feet have their own median plane; divides them into left and right sides
Frontal/Coronal Plane
divides the body into front and back (anterior and posterior)
Feet also have their own frontal/coronal plane
Transverse/Horizontal Plane
divides into top and bottom (superior and inferior)
Sagittal Plane (Brain)
divides into left/right
Frontal Coronal Plane (Brain)
divides into front and back (anterior/posterior)
Transverse/Horizontal Plane (Brain)
divides into superior/inferior (upper/lower)
Superior
nearer to top of head
Inferior
nearer to bottom of feet
Posterior
nearer to back
Anterior
nearer to front
Medial
nearer to mid-sagittal plane
Lateral
farther from mid-sagittal plane
Deep
farther from surface
Superficial
nearer to surface
Intermediate
between superficial and deep
Palmar vs Dorsal
Hand only
Palmar = anterior - glabrous skin (non hairy)
Dorsal = posterior - hairy skin
Plantar vs Dorsal
Feet only
Plantar = inferior - glabrous skin (non hairy_
Dorsal = superior - hairy skin
Proximal and Distal - Limbs
Proximal: nearer to trunk or point of origin (eg. elbow is proximal to the wrist (being nearer to the trunk))
Distal: farther from trunk or point of origin
Ipsilateral
on the same side
Contralateral
on opposite sides
Directions in the Brain
Dorsal = superior
Ventral = inferior
Rostral = anterior
Caudal = posterior
Directions in the Spinal Cord
Dorsal = posterior
Ventral = anterior
Rostral = superior
Caudal = inferior
Movement
Caused by muscle contraction and relaxation
Movement happens when joints rotate (flex, extend) and slide
Joints are surrounded by multiple muscles that pull in different directions
Joints rotate when the agonist muscle contracts and the antagonist muscles relax
Agonist Muscle
prime mover, muscle that contracts first
Antagonist Muscle
opposite of prime mover, muscle that relaxes to allow movement and contracts to stop movements
Contraction
muscle shortening; three types
Concentric Contraction
muscle actively shorten
Isometric Contraction
muscle maintains its length but can resist force; the joint does not move
Eccentric Contraction
muscle actively lengthens
Flexion
decrease joint angle from anatomical position
MUSCLE’S DON’T FLEX; JOINTS DO! (muscles contract)
Extension
increase joint angle, straightening
Hyper-Flexion and Hyper-Extension
joint rotation past the normal limit to joint range of motion
ABduction
movement away from median
ADduction
movement toward median
Circumduction
circular movement of joint
Internal Rotation
anterior surface rotates toward median plane
External Rotation
anterior surface rotates away from median plane
Shoulder Elevation
pull shoulders up
Shoulder Depression
pull shoulders down
Shoulder Protraction
curl shoulders in
Shoulder Retraction
pull shoulders back
Dorsiflextion
rotate foot up (pull toes up)
Plantarflexion
rotate foot down (point your toes)
Foor Eversion
roll plantar surface out
Inversion
roll plantar surface in
Hand Opposition
touching thumb with pinky
Hand Reposition
going back to anatomical from opposition
Supination
palm faces up (holding soup)
Pronation
palms facing down (pro-no I dropped my soup!)
Finger ABduction
spreading fingers
Finger ADduction
bringing fingers together to median plane
Thumb ABduction
bringing thumb away from the fingers forward
Thumb ADduction
bringing thumb back toward fingers
Thumb Extension
stretching the thumb away from fingers (high five)
Thumb Flexion
bringing thumb back into the palm (making four)
Neuroscience
Study of relationship between nervous system and behaviour
Systems Neuroscience
Study of brain regions, their function, and how they interact with other brain regions
Systems - what regions form functional groups?
Cognitive and Behavioural Neuroscience - how does the system function to produce behaviour?
Experimental Neuropsychology - how does that behaviour change when all or part of the system is damaged or diseased?
Nervous System - Physically
Central Nervous System - brain and spinal cord
Peripheral Nervous System - peripheral nerves
Nervous System - Functionally
Somatic Nervous System - sensory and motor systems (our focus)
Autonomic Nervous System - controlling visceral organs and glands that regulate physiological function, eg. heart/circulation, gut and digestive function, etc.
Spinal Cord Regions
Cervical - C1-C7 (enlargement; arms)
Thoracic - T1-T12
Lumbar - L1-L5 (enlargement; legs)
Cauda Equina
Sacral Region (S1-S5)
Dermatomes
Each level of the spinal cord receives information from certain areas of the skin on the body
Myotomes
Groups of muscles supplied by a single spinal nerve root
The myotomes usually underlie the dermatomes
White Matter in Spinal Cord
axons, neural tracts, pathways
Dorsal Columns
White Matter
Main ascending sensory tracts
Lateral and Ventral Columns
main descending motor tracts
Grey Matter in Spinal Cord
H-shaped central region containing neuron cell bodies
Dorsal horn
Sensory
Ventral Horn
Motor
Peripheral Neurons
Peripheral sensory neurons (afferents) have their cell bodies in the dorsal root
Efferent (motor) information descends from brain to spinal cord (upper motor neuron), then from spinal cord to muscle (lower motor neuron)
Three Major Brain Divisions
Brain Stem, Cerebellum, Cerebrum
Brain Stem “Divisions”
Diencephalon, Midbrain, Pons, Medulla
Hypothalamus
Brain Stem
Maintains body equilibrium by regulating endocrine (hormonal) system
Regulates food, water, temperature, vascular system (BP), and reproduction
Midbrain
Brain Stem
Superior and inferior colliculi → orienting to sights and sounds, respectively
Red nucleus → control proximal upper limb muscles
Pons
Brain Stem
Connects cortex to cerebellum (via cerebellar peduncle)
Vestibular Nuclei → control of eye and postural muscles
Reticular Nuclei → arousal, attention, circadian rhythm, control of postural muscles
Medulla
Brain Stem
Motor and sensory decussation
Vestibular Nuclei → control of eye and postural muscles
Reticular Nuclei → arousal, attention, circadian rhythm, control of postural muscles
Cerebellum
Plays an important role in movement performance by controlling muscle timing
Cerebrum
Composed of Basal Ganglia, Limbic System, and Gray/White Matter of Cerebral Cortex
Basal Ganglia
involved in controlling movement initiating and stillness
Limbic System
involved in controlling emotion, species-typical behaviours
Grey Matter (Cerebrum)
neuron and support cell bodies
White Matter (Cerebrum)
axons, myelin, support cells
Cerebral Cortex
Has all the lobes and stuff
Frontal (in front of Central Sulcus), Parietal (behind Central Sulcus), Occipital (behind Central Sulcus), and Temporal Lobes (under Lateral Fissure)
Upper Motor Neurons
CNS neurons that have their cell bodies in the cortex and carry efferent (motor) signal from cortex to spinal cord
Lower Motor Neurons
PNS neurons that have their cell bodies in the ventral horn and carry efferent info from spinal cord to muscle
AKA. Alpha Motor Neurons
Neurons Communicating Over Long Distances
Nerve cells communicate signals rapidly over short and long distances to:
Other neurons
Non-neural target cells (muscles, glands, organs)
Presynaptic neurons synapse (connect) with postsynaptic neurons at the dendrites of the postsynaptic cell body
Signalling depends on how the cell membrane (the outer structure of the cell) manage the concentration of charged ions inside and outside the cell
Axon Hillick: generates action potential
The Cell Membrane and Electrochemical Gradient at Rest
Plasma Membrane controls cell contents
Neurons are held together by a two-layered lipid plasma membrane (phospholipid bilayer)
Membrane control what can and can’t enter the cell
The membrane controls the passage of charged ions
Charged ions can’t pass through the cell membrane without an opening: ION CHANNELS!
Ion channels control the passage of charged ions
Ion channels to not transport ions; ions flow through by osmosis (according to their electrochemical gradients)
Ion channels are selective, controlling which ions pass and when they pass
Non-Gated Channels
leakage channels; open all the time
Gated Channels
open when specific conditions are filled
Voltage-Gated Channels
Eg. Sodium and Potassium Channels — IMPORTANT FOR ACTION POTENTIALS!
Mechanically-Gated Channels
eg. sensory receptors
Chemically-Gated Channels
gated from outside or inside the membrane
Neurotransmitter Activated
Calcium-Gated
ATP-Gated
About 100 different kinds of channels
Resting Membrane Potential
intra-and extracellular ion concentrations are different when the cell is at “rest”
Intracellular Concentration
Low Na+
High K+
Other compounds
So: low sodium, relatively negative intracellular environment
Extracellular Concentration
High Na+
Low K+
Other compounds
So: high sodium, relatively positive extracellular
Intra/Extracellular Concentration Difference
This difference is the electrochemical gradient of the resting membrane potential
These gradients set up the potential that drives diffusion/osmosis
Why Osmosis?
Fastest way to change cells electric potential
100k times faster than the next method
We want our CNS to be fast, so creating a situation where neurons rely on diffusion/osmosis is the way to go
Neurons set up the conditions for diffusion/osmosis by establishing the resting membrane potential