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What are the three functions of CSF?
Buoyancy:
Protection
Environmental stability
Where is CSF made?
CSF is produced by the choroid plexus in each brain ventricle.
What structures make up the choroid plexus?
Ependymal cells and capillaries within the pia mater.
How is CSF produced?
Blood plasma is filtered from capillaries and modified by ependymal cells.
How much CSF is produced per day?
Approximately 500 mL per day.
what are the 1st 3 places cerebrospinal fluid (CSF) travels to during circulation?
Lateral ventricles
Interventricular foramina
Third ventricle
what are the 2nd 3 places cerebrospinal fluid (CSF) travels to during circulation?
Cerebral aqueduct
Fourth ventricle
Subarachnoid space (around the brain and spinal cord)
what are the last 2 places cerebrospinal fluid (CSF) travels to during circulation?
Arachnoid villi absorb excess CSF
Dural venous sinuses return CSF to the blood
What is the full pattern of cerebrospinal fluid (CSF) circulation?
Lateral ventricles
Interventricular foramina
Third ventricle
Cerebral aqueduct
Fourth ventricle
Subarachnoid space (around the brain and spinal cord)
Arachnoid villi absorb excess CSF
Dural venous sinuses return CSF to the blood
what does CSF buoyancy do?
Buoyancy: Supports more than 95% of the brain’s weight.
what does CSF protection do?
Protection: Cushions the brain and spinal cord against sudden movements.
what does CSF environmental stability do?
Delivers nutrients and chemicals,
removes waste products,
protects nervous tissue from chemical fluctuations.
Olfactory nerve (CN I) motor innervation
None. It is purely somatic sensory, responsible for smell.
Optic nerve (CN II) motor innervation
None. It is purely somatic sensory, responsible for vision.
Oculomotor nerve (CN III) somatic motor innervation
Innervates four skeletal eye muscles:
Superior rectus
Inferior rectus
Medial rectus
Inferior oblique
Oculomotor nerve (CN III) parasympathetic/visceral motor innervation
Iris muscles and ciliary muscle.
Trochlear nerve (CN IV) somatic motor innervation
Superior oblique muscle.
Trigeminal nerve (CN V) somatic motor innervation
Muscles of mastication
masseter,
temporalis,
medial pterygoid,
and lateral pterygoid through the mandibular branch.
Abducens nerve (CN VI) somatic motor innervation
Lateral rectus muscle.
Facial nerve (CN VII) somatic motor innervation
Muscles of facial expression.
Facial nerve (CN VII) visceral motor innervation
Lacrimal gland, submandibular gland, and sublingual gland.
Vestibulocochlear nerve (CN VIII) motor innervation
None. It is purely somatic sensory for hearing and equilibrium.
Glossopharyngeal nerve (CN IX) somatic motor innervation
Stylopharyngeus muscle.
Glossopharyngeal nerve (CN IX) visceral motor innervation
Parotid salivary gland.
Vagus nerve (CN X) somatic motor innervation
Throat muscles and muscles involved in swallowing.
Vagus nerve (CN X) visceral motor innervation
Thoracic and abdominal organs.
Spinal accessory nerve (CN XI) somatic motor innervation
Trapezius and sternocleidomastoid muscles.
Hypoglossal nerve (CN XII) somatic motor innervation
Intrinsic and extrinsic tongue muscles.
Somatic motor vs. Visceral motor distinction
Purely sensory cranial nerves
Cranial nerves I (olfactory), II (optic), and VIII (vestibulocochlear).