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Histology
theory of tissues
Tissues
group of cells that perform a similar or related function
They improve the efficiency of operations because they enable tasks to be shared amongst various specialized cells
Four tissue groups
epithelial, connective, muscle, and nervous
epithelial tissue
Organized into single or layered sheets of cells
lines internal and external surfaces
protects underlying structures from wear, infection, and pressure
packed close together with little or no intercellular material between them
may be ciliated for absorption, secretion, or filtration
Simple (epi)
singled layered
stratified (epi)
two or more layers
squamous (epi)
flat
cuboidal (epi)
roughly cube-shaped
columnar (epi)
column shaped
transitional (epi)
varying shapes that stretch
Simple squamous epithelium
Structure= single layer of flat cells
Function = transport and absorption, diffusion, filtration
Location= lining of blood & lymphatic vessels
Stratified squamous epithelium
structure=several layers of closely packed cells, outer layer is flattened cells
function= protection against microtubles
location= surfaces of lining of mouth, esophagus, surface of skin
Simple columnar epithelium
structure= arranged in single layer
function= secretion and absorption of nutrients
location= line stomach and intestines, respiratory, and reproductive tracts
simple cuboidal
structure= cube shaped cells in a single layer
function= secretion and absorption
location= glands and kidney tubules
pseudostratified epithelium
structure= single layer of tall cells that appear layered because of different heights
function= protection against dust or foreign particles into the lungs
location= surface of lining of trachea
stratified transitional epithelium
structure= many layers of tall cells that have cells of various shapes, capsule of stretching
function= protection
location= urinary bladder
muscle tissue
highly specialized cells called fibers
features of muscle tissue
contractile
responsible for both voluntary and involuntary movements
Cardiac muscle (muscle tissue)
Structure:
striated involuntary
cylindrical, branching cells interconnected
One centralized nucleus
Location: Wall of the heart
skeletal muscle
Structure:
striated voluntary
large, long, cells
multiple peripheral nuclei.
Location: muscles attached to bones
smooth muscle
Structure:
non-striated involuntary
spindle-shaped cells
single central nucleus.
Location: lining of GI tract, ducts of glands, walls of blood vessels, eye muscles
Connective tissue
major supporting tissue of the body
most varied
location= found in skin, membrane, muscle, bones
function= binds other structures together, provide support, and protection against damages, infection, or heat loss
6 types of CT
areolar connective tissue
adipose(fat)
fibrous
bone
cartilage
blood and hematopoietic tissue
proper/ordinary CT
loose CT
areolar and adipose
dense CT
fibrous CT
specialized CT
supportive CT
cartilage and bone
fluid
blood and hematopoietic
Areolar CT
most widely distributed CT
“glue” that gives form to internal organs
delicate web of fibers
variety of cells in loose matrix
adipose (fat CT)
store lipids
contains large fat compartments in cells
fibrous CT
Bundles of strong white collagen fibers arranged in parallel rows; dense
Composes tendons & ligaments
Provides strength & flexibility, does not stretch
Anchors muscles to bones
Bone (CT)
most highly specialized forms of CT
matrix is hard and calcified
forms building blocks called osteons
stores calcium and provides support and protection
cartilage (CT)
matrix is consistency of firm plastic
flexible with embedded chondrocytes
found in nasal septum and ear
blood (CT)
matrix is liquid
transportional and protective functions
red and white blood cells
found in blood vessels
hematopoietic tissue
blood-like CT in red marrow cavities of bones and organs such as lymph nodes
fomation of blood cells and lymphatic cells to defend against disease
Neruons (nervous tissue)
structural and functional cells of NS
specialized to transmit and receive nerve impulses
neuroglia (NT)
supporting and connecting cells of the NS
highly branched supportive cells, which do not conduct nerve impulses
Tissue Repair
epithelial and CT= regenerate
muscle and neruons= limited abilities
neurons in the brain and spinal cord= do not grow back
Skin
the body’s largest organ
thermoregulation
cooling by sweating, heating by flattening the fair
sensory reception
the skin senses touch, heat, vibration, pressure, and pain for information about changes in the environment
vitamin manufacture
the skin absorbs UVB lights to synthesize
Epidermis
outermost layer of skin, consists of stratified squamous epithelium with up to 5 layers of skin
dermis
deeper layer of skin, made up of primarily connective tissues, fiber and collagen
structure of skin
cells flatten and become keratinized as they migrate from the basal layer to the surface
stratum corneum (epidermis)
dead skin cells flake off and replaced with skin below
stratum lucidum(epidermis)
in thick skin, now in all skin, in palms, soles of feet, an additional layer
stratum granulosum(epidermis)
granular, cells getting compressed and dying
stratum spinosum(epidermis)
spiky appearance with dyes
stratum basale(epidermid)
holds epidermis onto dermis below it, mitosis living layer
dermal papillae(dermis)
projections that are important to keep the dermis and dermis together. They form ridges and grooves that make fingerprints unique
deeper areas of dermis filled with
collage fibers(strength), elastic fibers(flexibility and ability to stretch), reticular fibers(support), nerves and nerve endings, muscle fibers(arrector pili),
3 types of finger prints
arches, whorls, and loops
arches
the ridges extend from one side of the finger to the other, rising in the center
whorls
the ridges are in a circular pattern
loops
one or more ridges enter from one side of your impression, curves, and leaves from the same side.
hair
grows from a called the hair follicle, hair growths begins from hair papilla(base of follice)
arrector pili muscle(hair)
specialized smooth muscle that moves hair and causes hair to stand up straight, goosebumps
receptors
specialized nerve endings allow for sensations of touch, pain, temperature, and pressure
meissner’s corpuscle(receptors)
superficial nerves, capable of detecting light touch
pacinian corpuscle(receptors)
deep nerves, capabel of detecting pressure
nails
made of keratin, hidden part is the root and is hidden by the cuticle
eccrine(sweat glands)
small, numerous, and widespread throughout the body, produce sweat and body temperature
apocrine sweat glands
larger than eccrine, found primarily in axillary and pelvic regions, begin to function at puberty, secrete a thick secretion
sebaceous glands
secrete oil to lubricate hair and skin, sebum accumulation in follicles= acne and blackheads
squamous cell carcinoma(skin cancer)
malignant tumor of the epidermis
basal cell carcinoma(skin cancer)
less likely to metastasize; usually on upper face, begins in cells at base epidermis(basal layer)
melanoma(skin cancer)
malignant, most serious form of skin cancer, develops from pigmented moles and transforms into dark, spreading lesions.