Grading and staging

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10 Terms

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Tumor grading
Evaluation of tumor-cell maturity and differentiation under a microscope
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Grade I tumor
Well-differentiated tumor that closely resembles normal cells
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Grade II tumor
Tumor with an intermediate degree of differentiation
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Grade III tumor
Moderately to poorly differentiated tumor
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Grade IV tumor
Very poorly differentiated or undifferentiated tumor
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Tumor staging
Evaluation of the extent of tumor spread in the body
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TNM system
Staging system based on tumor, regional lymph nodes, and distant metastasis
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T in TNM
Tumor size and degree of local extension
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N in TNM
Regional lymph nodes involved by tumor cells
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M in TNM
Spread of tumor cells to distant sites