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What is included on a lab slip
Pt name
DOB
Date ordered
ICD 10 code
CPT codes
Match ICD 10s
Needed for reimbursement
For elimination of fraud and abuse
Accuracy
closeness to the true value
precision
reproducibility of results
specificity
true negatives
useful for confirming new dx
will have few false positives if good
sensitivity
true positives
useful to exclude diagnoses
few false negatives
use of predictive values
determine whether or not a patient has a disease based on lab results
positive predictive value
indicates likelihood pt has disease
# of true positives
negative predictive value
indicates likelihood pt does not have disease
# of true negatives
BMP includes
Na
K
BUN
Creatinine
GFR
Glucose
Ca
Cl
Bicarb
what % of errors are pre-analytical
75%
Disadvantages of POCT
Quality
Results aren't as good
More expensive
neutrophils indicate
signs of infection or inflammation
usually bacterial
lymphocytes indicate
infections/immune response
more viral
hematological cancers
eosinophils indicate
allergies
basophils indicate
allergic reactions
autoimmune disease
Na indicates
fluid balance
nerve/muscle function
abruptly low = seizures
K indicates
muscle function
nerve signals
cardiac rhythms
What additional tests are in a CMP
Albumin
total protein
AST
ALT
Total bilirubin
ALP
best tests for liver function concern w/ abdominal pain
bilirubin
AST
ALT
3 causes of artifact
1. patient movement
2. hardware
3. software - or operator use
Positive contrast agents
enhance imaging
examples of positive contrasts
barium
iodinated agents
purpose of intravascular contrast agents
in CT - visualization of hypervascular tissue and vascular structures
most common generation of intravascular contrast
second generation
less adverse reactions, more tolerable
Omnipaque
third generation contrast agents
those with high risk of contrast-induced nephrotoxicity
Visipaque
Planar imaging
shadows of complex 3D objects
compressing large objects into 2D images
example of planar imaging
radiography
cross-sectional imaging
addresses 3D structures by making 2D slices
images can be 2D or 3D
examples of cross-sectional imaging
CT, US, MRI
most vs. least expensive scan
most = MRI
least = x-ray
radiography includes
x-ray
fluoroscopy
oldest radiology testing
radiography (x-ray)
best use of x-rays
observe bones
main disadvantage of x-ray
collapses 3D structures into 2D
fluoroscopy
projectional radiography for real-time observation of structures
uses of fluoroscopy
GI imaging (swallowing)
Interventional radiology (heart cath)
MSK radiology
CT scan
Cross-sectional imaging to ID greater range of abnormalities in the body
rapidly rotating x-ray tube
air embolism
risk of CT contrast
-rare
-large air bubble enters via hand injection
nephrotoxicity
risk of CT contrast
-acute renal dysfunction 2-3d after IV admin
-rare
contrast excavation
risk of CT contrast
-contrast is toxic to soft tissues
-localized inflammation
-ulcers, necrosis, compartment syndrome if severe
metformin and IV contrast dye
if acute renal failure develops, can lead to lactic acidosis
-hold metformin 48hrs before and after CT scan
It is important to check for this in women before giving CT scan
pregnancy
especially early! safer in later trimesters
what method has the most radiation exposure
CT scan
how does US work
passing sound waves into tissue and analyzing reflected waves
uses gray-scale
important uses of US
doppler analysis for blood flow
differentiation between cysts and solid lesions
contrast for US
definity or optison
used for evaluating the heart
bubble studies
US
cardiac use
helps look for holes in the heart
3 pieces of tech for US
transducer
console
CPU
limitation of US
depends on the tech being very skilled
what differentiates best between cysts and solid lesions
US
what is the gold standard to dx testicular and ovarian torsion
US
cons of US
-depends on operator skill
-limited eval of deep structures
-hard to see structures deep to gas - like lungs
use of contrast on MRI
enhance tumors and reduce inflammation
primary for MSK and spine imaging - distinguishes discs, muscles, ligaments, and tendons
MRA vs CTA
MRA = blood vessel visualization via MRI
CTA = blood vessel visualization via CT
most common MRI contrast
Gadolinium
Nephrogenic system fibrosis (NSF)
complication of gadolinium contrast in MRI
-high morbidity and mortality
-pt w/ stage IV or V CKD and AKI
pros of MRI
great for soft tissue contrast
no radiation exposure
patients to limit radiation in
pregnant women, especially early
patients of reproductive age
children
imaging with radiation
X-ray
CT
Nuclear medicine