Endo Exam 2: Insulin Meds (Class, When to Give, MOA)

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25 Terms

1
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Which class of medications are these?

  • Aspart

  • Lispro

  • Afrezza


Ultra-Rapid

2
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Which class of medications are these?

  • Fiasp

  • Lyumjev

  • Afrezza


Ultra-Rapid

3
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Which class of medications are these?

  • Aspart

  • Lispro

  • Glulisine


Rapid

4
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Which class of medications are these?

  • Novolog

  • Humalog

  • Admelog

  • Apidra


Rapid

5
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Which class of medications are these?

  • Regular


Short

6
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Which class of medications are these?

  • Humulin R

  • Novolin R


Short

7
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Which class of medications are these?

  • NPH


Intermediate

8
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Which class of medications are these?

  • Humulin N

  • Novolin N

  • ReliOn


Intermediate

9
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Which class of medications are these?

  • Glargine

  • Degludec


Long

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Which class of medications are these?

  • Lantus

  • Basglar

  • Semglee

  • Rezvoglar

  • Toujeo U-300

  • Tresiba


Long

11
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Which class of medications are these?

  • Icodec

  • Efsitora


Weekly Basal (T2DM ONLY)

12
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Which class of medications are these?

  • Awiqli

  • Novo

  • Onswik

  • Lilly


Weekly Basal (T2DM ONLY)

13
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Which class of medications are these?

  • 70/30 NPH/Regular (HUMULIN, NOVOLIN, ReliOn)

  • 70/30 aspart (NOVOLOG)

  • 75/25 and 50/50 lispro (HUMALOG)


Premixed

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Give: With the 1st bite, up to 20 min after starting

Ultra-Rapid

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Give: at start of meal

Afrezza

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Give: ≤ 15 min BEFORE the meal

Rapid

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Give: 30 min BEFORE the meal

Short

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Give: 1–2x/day

Intermediate

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Give: Once DAILY

Long

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Give: Once WEEKLY

Weekly basal

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Give: BID BEFORE breakfast and dinner

Premixed

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_____: 30 min BEFORE the meal. 

_____: 15 min BEFORE the meal.

Human 70/30, Analog Mixes

23
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Order fastest to longest (knowledge check): _____ → _____ → _____ → _____

Lispro/Aspart, Regular, NPH, Glargine/Degludec

24
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DIMERS blocked = _____

FA = albumin = _____

pH CHANGE = DEPOT = _____

PROTAMINE = _____

Fc = _____

Fast, Long, Glargine (Lantus), NPH, Efsitora (Onswik)

25
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HEXAMERS in presence of PHENOL (polyols) = _____

C20 LINKER + ALBUMIN Binding = _____

2 ARG GLY + pH 4 in formulation SOLUBLE after SQ = _____

AA Sub. AND L-ARGININE = prevent DIMERS = _____

LOWER risk of DELAYED HYPOglycemia and better glycemic CONTROL AFTER meal = _____

Degludec (Tresiba), Icodec, Glargine (lantus), Ultra-Rapid Aspart (Liasp) and NPH, Glulisine (Apidra)