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working memory
o Information: Goal-relevant, short timeframe
o Location: Prefrontal and temporoparietal association cortex
working memory
o Temporary storage and manipulation of information
o Essential for language, problem-solving, mental navigation, reasoning
o Complex mental multitasking requires working memory
o Central to cognition
Encoding, Consolidation, Retrieval
Three stages of declarative memory
declarative memory
o Information: Facts, events, concepts, locations
o Location: Lateral prefrontal cortex and medial temporal lobe
declarative memory
o Conscious
o Recollections that can be easily verbalized
o Requires attention during recall
Immediate: 1-2 sec
Short term: brief storage, lose in 1 min
Long-term: relatively permanent storage
episodic, semantic
What are the two types of declarative memory?
episodic memory
- Collection of specific personal events
- Who, where, why, when
semantic memory
- Acquired concepts/common knowledge
- Not based on personal experience
- Examples: letter sounds, number concepts
procedural memory
o Information: Skilled movements and habits
o Location: Frontal cortex, thalamus, basal ganglia
o Automatic, unconscious
procedural memory
o Requires practice
o The activity needs attention until mastered, then more automatic
o Accessed through unconscious systems such as movement or perception
memory creation
Synapses are formed and strengthened through practice (motor learning and neuroplasticity)
attention, emotion, arousal, linking old and new information, reviewing
memory is enhanced by:
distraction, stress, disinterest
memory is reduced by:
alertness
o Degree to which pt is awake, aroused, and attentive
awareness
o Ability to perceive or be aware of a fact, occurrence, or event
arousal
o Physiologic readiness for activity
attention
o Ability to focus consciousness on specific information
o Influenced by arousal, awareness, and motivation
brainstem
What structure regulates consciousness?
thalamus
regulates arousal, attention, awareness, thinking, motor behavior
cerebral cortex
regulates attention and generalized arousal
arousal, attention, vigilance, voluntary, attention, motor
Role that the following neurotransmitters and neuromodulators play in consciousness:
-Serotonin: general _______
-Norepinephrine: _________ and _________ (fight or flight)
-Acetylcholine: _________ direction of _________ toward an object
Dopamine: initiation of _____ or cognitive actions
alert
Level of Consciousness:
o Awake and attentive
lethargic
Level of Consciousness:
o Drowsy and falls asleep easily
o Difficulty maintaining attention
o May have to use loud voice to keep pt awake and engaged
delirium
Level of Consciousness:
o Often seen as pt emerges from coma
o Characterized by confusion with circumstances. May hallucinate or act as if in a dream. Conversation may not make sense
obtunded
Level of Consciousness:
o Difficult to arouse from sleep
o Requires repeated stimulation
stupor
Level of Consciousness:
o Responds only to noxious stimuli
o Quickly returns to unconsciousness if stimulation stops
o Unable to interact when aroused
coma
Level of Consciousness:
o Pt cannot be roused even with noxious stimuli
o Reflex motor responses may be seen
selective attention
o Ability to select important/relevant information while ignoring other sources of information
divided attention
o Ability to process more than one source of information or multitask; reflects that the skill may be more procedural (automated)
alternating attention
o Attention switching between two tasks or sources of information as needed
sustained attention
o Ability to pay attention over a period of time without losing interest or focus/vigilance
intellect
o Ability to form concepts and to reason
o Involves memory and ability to process mental events
o Scores on psychologic tests of intellect are unrelated to reality
frontal, parietal, temporal, cerebellum, temporal, cerebellum
Brain regions with influences on intellect:
- Core regions of _______ and ________, but require strong networks and ability to work in concert with other regions
- Frontal lobe especially with strong connections to which lobe?
- Parietal lobe with strong networks to what?
- Which region for visuomotor ability?
drive, education, socialization, social awareness
What four influences on intellect were described in the lecture?
prefrontal cortex, basal ganglia, thalamus
What three brain regions/structures were described as involved in goal-directed behavior?
basal ganglia
What brain structure was mentioned as involved with motivation?
frontal lobe, thalamus, hippocampus, amygdala, hypothalamus
Which parts of the limbic system were mentioned as involved with emotion?
emotional, emotions,
Medial prefrontal association cortex
-Identifies _________ stimuli, generates and perceives ________
(readings other's emotions and intentions)
emotional loop
o Prefrontal cortex, basal ganglia, thalamus
o Links emotion, cognitive, and motor systems
o Involved in reward-seeking behavior
behavior
o Medial prefrontal cortex and limbic system
o Ventral prefrontal cortex and social behavioral loop
mood, affect
Prefrontal cortex and social behavior loop connect areas regulating ____ and ______