MCB - nervous system diseases

meningitis

inflammation of the meninges

causes fever, headache, vomiting, stiff neck

impact blood-brain barrier

encephalitis

brain infection

meningoencephalitis

inflammation of meninges and brain

bacterial meningitis - caused by:

Streptococcus pneumoniae

haemophilus influenzae

neisseria meningitidis

viral meningitis

less severe, more common, no treatment

fungal meningitis

caused by cryptococcus neoformans

affects immunocompromised ppl

listeriosis

foodborne meningitis

caused by Listeria monocytogenes

tetanus

caused by clostridium tetani endospores

causes muscle spasms and lock jaw

Botulinum

caused by clostridium botulinum exotoxin

Leprosy (Hansen’s disease)

caused by mycobacterium

Poliomyelitis

caused by poliovirus

affects motor neurons

rabies

zoonotic disease caused by rabies virus

transmitted through animal bites

post-exposure prophylaxis

repeated rabies vaccine injections and human rabies immunoglobulin

arboviral encephalitis

transmitted by mosquitos

prions

TSEs, mad cow disease, scrapie, Cruetzfeldt-Jakob disease, kuru