Section 6: Citric Acid Cycle Overview + Steps 1–4 lecture 15

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12 Terms

1
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What is the purpose of the citric acid cycle?
Oxidize acetyl-CoA and generate high-energy carriers.
2
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What other names are used for the citric acid cycle?
TCA cycle and Krebs cycle.
3
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Where does the citric acid cycle occur?
Mitochondrial matrix.
4
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What enters the citric acid cycle?
Acetyl-CoA.
5
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What happens in TCA step 1?
Acetyl-CoA + oxaloacetate → citrate.
6
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What enzyme catalyzes TCA step 1?
Citrate synthase.
7
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What happens in TCA step 2?
Citrate → isocitrate.
8
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What enzyme catalyzes TCA step 2?
Aconitase.
9
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What happens in TCA step 3?
Isocitrate → alpha-ketoglutarate; NADH and CO2 are produced.
10
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What enzyme catalyzes TCA step 3?
Isocitrate dehydrogenase.
11
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What happens in TCA step 4?
Alpha-ketoglutarate → succinyl-CoA; NADH and CO2 are produced.
12
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What enzyme catalyzes TCA step 4?
Alpha-ketoglutarate dehydrogenase complex.