Polyethylene glycol 3350

Polyethylene glycol 3350 is the active ingredient found in which of the following brand-name products? A. Lactulose B. Golytely, NuLytely, MoviPrep, Plenvu C. Senokot D. Dulcolax

B. Golytely, NuLytely, MoviPrep, Plenvu

Which of the following are FDA-approved or common indications for polyethylene glycol 3350? A. Irritable bowel syndrome B. Colonoscopy preparation and constipation C. Acute pancreatitis D. Ulcerative colitis flare

B. Colonoscopy preparation and constipation

Which dosage form and strength is available for polyethylene glycol 3350? A. Oral tablet: 5 mg, 10 mg B. Rectal suppository: 10 mg C. Powder for oral solution: 100–420 g D. Oral capsule: 250 mg

C. Powder for oral solution: 100–420 g

What is the mechanism of action of polyethylene glycol 3350? A. Stimulant laxative that increases intestinal motility B. Stool softener that reduces surface tension C. Hyperosmotic laxative D. Chloride channel activator

C. Hyperosmotic laxative

How should polyethylene glycol 3350 be dosed in patients with renal impairment? A. Avoid use in severe renal impairment B. Reduce dose by 50% C. Increase fluid intake but reduce dose D. No dose adjustment required

D. No dose adjustment required

Which of the following are contraindications to polyethylene glycol 3350 therapy? (Select ALL that apply) A. Bowel perforation B. Gastric retention C. GI obstruction D. Chronic constipation E. Dehydration

A, B, C

Which counseling points are MOST appropriate for a patient using polyethylene glycol 3350 for colonoscopy preparation? (Select ALL that apply) A. Shake the container before use B. If severe bloating occurs, slow the rate of consumption C. Avoid solid foods for 3–4 hours before beginning treatment D. Take with a high-fat meal to improve absorption E. Expect immediate relief within 10 minutes

A, B, C

Which of the following are potential adverse effects of polyethylene glycol 3350? (Select ALL that apply) A. Anal irritation B. Bloating C. Nausea D. Anaphylaxis E. Dehydration F. Seizures

A, B, C, D, E, F

Which black box warning applies to polyethylene glycol 3350? A. Risk of severe electrolyte imbalance B. Increased risk of colon perforation C. Risk of severe dehydration D. None

D. None