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Ventilation
Air exchange between environment and
lung sacs
• O2 and CO2 exchange between alveoli
and blood
• O2 and CO2 exchange between blood
and tissues
If there is too much CO2 in alveolus, too little O2 for blood to pick up,
causes
Vasoconstriction to reduce blood flow
•Bronchodilation to increase airflow
If there is too little CO2 in alveolus, too much O2 for blood to pick it all
up, causes:
Vasodilation to increase blood flow
Bronchoconstriction to decrease airflow
Control of Respiration feedback loop

Chemical formula

2 types of Chemoreceptors
peripheral
central
peripheral Chemoreceptors
Located in arteries (carotid, aorta)
• Detect level of CO2 in blood as carbonic acid (H+ ions)
Central chemoreceptors
• Located in medulla
• Detects level of CO2 in blood
-Only CO2 can pass blood-brain barrier
2 parts of the respiratory center
Medullary respiratory center
Pontine respiratory group
Medullary respiratory center
Stimulates diaphragm and
intercostal/abdominal muscles for
breathing
Pontine respiratory group
• Involved with switching between
inspiration and expiration
• Affects rate and tidal volume
Tidal volume
the amount of air that moves in or out of the lungs with each normal, quiet breath
Dead Space
• Volume of air inhaled that does not
participate in gas exchange
• Air in conducting airways (trachea, bronchi,
etc)
• Air in not properly perfused alveol
Dead space picture

Emphysema causes shortness of breath because
long-term damage destroys the thin walls of the lungs' tiny air sacs (alveoli), making them lose their stretchiness and rupture.
significant loss in elastic recoil
vital capaity
the maximum amount of air a person can exhale after taking a deepest possible inhalation
negative feedback loop

Alveolar sacs
clusters of tiny, cup-shaped air spaces located at the very end of the respiratory tree in the lungs
surfacant
aqueous film that cover alveolar sacs to make sure they dont stick together.
atelactasis
the partial or complete collapse of a lung or a lobe of a lung
2 phases of ventilation
inspiration
expiration
inspirations occurs as the
external intercostal muscles and diaphragm contract