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Contact Precautions
May include but not limited to: Presence of stool incontinence, Norovirus, Rotavirus, Clostridium difficile(C-Diff), Draining wounds, Uncontrolled secretions, Bedbugs/head lice
Hand hygiene with soap and water – sanitizer does not suffice! Disinfect used equipment with a bleach wipe, PPE-
Contact PPE
Gloves, Gown, Do not wear the same gown and gloves for the care of more than one person
Droplet
can be generated from the source person during coughing, sneezing, talking and during the performance of certain procedures such as oral suctioning
may contain microorganisms and generally travel no more than 3 feet from the patient. These can be deposited on the host’s nasal mucosa, conjunctivae or mouth
Droplet Conditions
Conditions include, but are not limited to: Pertussis, Influenza, RSV, Diphtheria, invasive Neisseria meningitidis
Droplet PPE
Gloves, Surgical mask, Do not wear the same PPE for the care of more than one person, Source control: put a mask on the patient if patient agreeable
Airborne
Transmission occurs through the dissemination of either: Airborne droplet nuclei (small-particles containing microorganisms that remain suspended in the air for long periods of time), Dust particles that contain an infectious agent. Applies to patients known or suspected to be infected with microorganisms transmitted by airborne droplet nuclei
Airborne Conditions
Measles, COVID-19, Severe Acute Respiratory Syndrome (SARS), Varicella (chickenpox), Mycobacterium tuberculosis
Airborne PPE
Patients may be placed in specially-ventilated negative pressure rooms, PPE- Gloves, Fitted N95 or Powered-Air Purifying Respirator (PAPR) hood, Do not wear the same PPE for the care of more than one person, Source control: put a mask on the patient if patient agreeable; patient's door should remain closed
Neutropenia
Condition characterized by a low number of neutrophils in blood causing individual to be an increased risk for acquiring infection
• Compromised immune system, Blood cancers, Chemotherapy and radiation, Hemodialysis, HIV or autoimmune diseases, Neutropenic precautions
Neutropenic precautions
Hand hygiene pre/post session, before and after touching items in the environment without gloves, and when visibly soiled, Surgical mask before entering room and throughout session, No live flowers or plants in the room (They can harbor bacteria and fungal spores that pose an infection risk to individuals with weakened immune systems)
Medication classes typically seen in OT and use
Analgesics: Pain relief, Acetaminophen (Tylenol), NSAIDs (Ibuprofen, aspirin), Oxycodone, Morphine, Dilaudid
Neuropathic agents: Gabapentin
Muscle relaxants: Cyclobenzaprine (Flexeril), Methocarbamol (Robaxin), Baclofen (Botox)
Anticoagulants (Blood thinners): Warfarin, Heparin, Lovenox
Antihemorrhagics: Thrombin
Antihypertensives: Lisinopril, Amlodipine, Metroprolol, Hydrochlorothiazide (*also a diuretic), Metolazone (*also a diuretic)
Diuretics: Furosemide (Lasix), Bumetanide (Bumex)
Arrhythmias
Ventricular tachycardia: Characterized by regular rhythm and rate, QRS complexes wide and bizarre, P waves not discernible, can be caused by MI
Ventricular fibrillation: Ventricular rhythm and rate are rapid and chaotic, can be caused by MI
Atrial fibrillation: Uncoordinated, irregular contraction, resulting in "quivering" of chamber, characterized by irregular, rapid rhythm
Asystole: severe form of cardiac arrest where the heart's electrical and mechanical activity stops entirely, showing as a flat line on an electrocardiogram
Labs
Troponin: Proteins are normally only found in skeletal muscles and heart, but can leak into bloodstream when heart has been damaged. Observe trend of troponin levels; Increasing levels may indicate cardiac insult
Hemoglobin: Assists in assessing abnormal states of tissue oxygenation, anemia, blood loss. Symptoms-based approach to treatment (12-18 g/dL normal)
Low hemoglobin <8 g/dL may result in decreased endurance, activity tolerance, tachycardia. <7 g/dL: Consider deferring out of bed activity
Vitals
SPO2 norms: between 92% - 100%, SpO2 values below 92% are considered to be abnormal, and caution should be taken at these values
Some people with chronic lung disease or sleep apnea can have normal levels around 90%
Patients with an SpO2 reading of less than 92% are considered hypoxemic
Patients with an SpO2 reading of less than 85% would be severely hypoxemic (These patients would most likely need an external oxygen supply)
Lines/Drains
NG Tubes: Medical catheter that’s inserted through nose, travels to stomach
Single lumen = single-channel tube ("one-way")
Double lumen = two-channel tube ("two-way")
Used for temporary periods to deliver substances such as food or medications to your stomach, Can also be used to draw substances out
Contraindications
Maintain aspiration precautions at all times: Client should remain at upright angle (30 degrees or more), defer therapy if tube is dislodged, defer therapy if tube has been recently placed without x-ray to confirm placement
Arterial line
Monitoring of continuous arterial bp, blood sampling, and administration of medicines, vasopressors (increase bp meds), no ROM at area of insertion (when inserted in femoral artery, limit hip flexion)
• Needs to be recalibrated by nursing once patient has mobilized out of bed
• If line is dislodged/pulled, it is a medical emergency; apply pressure and notify nursing immediately
Central line
Often inserted into the jugular, subclavian, or femoral vein and rests in the proximal artery
• Precautions: Limit excessive ROM, If central line becomes dislodged/pulled it is a medical emergency, apply pressure and notify the nurse immediately
PICC line
in a large peripheral vein in the arm, passes through the superior vena cava near the heart, no bp in extremities, can’t get dressing wet, no resistive exercises on that arm, it is a medical emergency if the line gets dislodged
Peripheral IV
inserted into a vein usually through the hand or arm, can become dislodged, apply pressure and tell nurse immediately
DVT (Deep Vein Thrombosis)
Occurs when a blood clot (thrombus) develops in a vein deep in the body, often in the calf, thigh, or pelvis
• May partially or completely block blood flow through the vein, swelling of leg or arm on one side (sometimes, this happens suddenly), diagnosed through Doppler ultrasound, venogram, or d-dimer test, can lead to PE
Contractures
Occurs when scarring (of skin) or fibrosis (of ligaments or muscles) makes soft tissues tighten and stiffen, resulting in permanent reductions to ROM
Usually happens when the tissues try to repair themselves after injury or after wasting away from disuse
Medical Management for Contractures
Braces, casts and splints, Serial casting: Muscle/tendon is immobilized in lengthened position, Myofascial release, Anti-inflammatory drugs
Surgery:
Tenotomy ("tendon lengthening") Makes small cuts or holes in the tendon to release tension. As the tendon repairs itself, it can grow back longer.
Tendon transfer: Removes the contracted tendon and transfers another tendon from a donor or from elsewhere in the body
Arthroplasty (for joint capsule contractures): Surgery to replace parts of or the full joint capsule
Fasciotomy (for contractures that involve fascia, like Dupuytren’s contracture): Surgeons cut holes in the fascia to release it or remove pieces of scar tissue. Example: "Z-plasty" - Zig-zag cuts are made to encourage the tissue to repair itself without shrinking.
Plastic surgery (for scar contractures): Scarred tissue is removed and replaced with a skin graft or skin flap taken from a donor or from elsewhere on the body
OT role in contractures
Orthotics/serial casting
• Preventative: Early mobilization, Positioning, PROM of immobile body parts/joints
Heterotopic ossificans
Occurs when bone tissue develops in the soft tissues, presents as a bony, painful lump that develops underneath the skin, Often, people get HO after an injury or major surgery, Genetic HO is rarer and more severe, If the lump is near a joint, it may restrict ROM
Activity orders on Trauma
§ ROM restrictions
· Types of ROM allowed
o Ex. AROM or PROM only?
· Planes of ROM allowed
o Ex. Flexion and abduction only?
§ Weight bearing statuses
· Non–weight bearing (NWB) - 0% weight
· Touchdown weight bearing (TDWB) - 10%–15% weight
· Partial weight bearing (PWB) - 30%-50% weight
o Some surgeon protocols do not specify percentage – Always best to clarify!
· Weight bearing as-tolerated (WBAT) / Full weight bearing (FWB) - 100% weight as tolerated
§ Braces/orthotics
· Ordered for the patient
o Ex. Knee immobilizer, hip abduction brace, CAM boot, etc
§ Additional info:
· When surgeon’s protocol requires complete rest of injured tendon, bone, or joint, ROM measurements are deferred until movement is permissible.
· When client is on specific program (e.g., controlled ROM), therapist:
o Measures joint, adhering to precautionary boundaries
o Does not allow client to exceed limits of surgeon’s prescription.
· Assessing strength after fracture or surgery—only be performed when ordered by orthopedist
Intercondylar Fractures
Volkmann’s ischemia
• Compartment syndrome of the forearm
• Signs of ischemia include severe pain with passive stretching of fingers; pale, bluish skin color; absence of forearm radial pulse; pins and needles; and decreased hand sensation and paralysis
• Immediate medical action is important if Volkmann’s ischemia is suspected. The common surgical approach includes decompressive fasciotomy.
Ligament Injuries (Grades 1-3)
Grade 1
• structural damage only on microscopic level, with slight local tenderness and without joint instability
• May produce discomfort during activities—requiring rest, thermal modalities, and temporary modifications to work, ADL, and leisure activities.
Grade 2
• Partial tear (rupture) of the ligament, visible swelling and noticeable tenderness, but without joint instability (or with mild instability)
• Require longer immobilization until ligament fibers are healed—gentle protected (functional) movement encouraged, within anatomical lines, to maintain joint flexibility but prevent reinjury.
oSplinting for immobilization if indicated, gentle ROM within prescribed limits, ROM/strengthening and edema management at unaffected joints, re-conditioning affected joint once cleared by physician
Grade 3
• Complete rupture of the ligament with significant swelling and with instability of the joint
• Require surgical intervention to reattach ligament to bone with OT to improve functional use of hand following full healing.
• Splinting for immobilization, ROM/strengthening and edema management at unaffected joints, re-conditioning affected joint once cleared by physician
Nerve lesions
abnormal growth of nerve tissues after the nerve is injured
Ulnar nerve lesion
•Laceration of ulnar nerve at wrist, a low ulnar lesion, results in loss of most of hand intrinsics. Denervation of abductor digiti minimi, flexor digiti minimi, & opponens digiti minimi results in flattening of hand with loss of distal transverse metacarpal arch.
•Ring and small fingers present a “claw hand” deformity.
Median nerve lesion
•Laceration at wrist results in low median nerve palsy, with denervation of opponens pollicis and abductor pollicis brevis and lumbricals to index and long fingers.
•Motor and sensory input
•Results in “ape hand” deformity
Radial nerve lesion
•High radial nerve injury often occurs with humeral fractures as nerve spirals around humerus. Damage to radial nerve in this area leads to absent wrist, digital extensors, and “wrist drop” deformity.
•Weak finger and wrist extension muscles
Causes of Amputation
• Dysvascular disease (54%) - poor blood flow to limb, causes tissues to die
• Trauma (45%) - lost because of injury or accident
• Cancer (approx. 1%) - cannot be treated while actively preserving the limb
Phantom limb pain vs. phantom limb sensation
Phantom Limb Sensation—nonpainful sensation experienced in missing limb.
Described as a sense of phantom limb: (a) still present, (b) temperature changes, (c) itching, (d) pressure, and (e) tingling.
Phantom Limb Pain – Painful sensation described as burning, shooting, or cramping sensation in the phantom limb
Exact cause unknown – thought to be neuropathic in nature due to disruption to central and peripheral nervous systems
Levels/Types of Burns
• Superficial (old 1st degree) - epidermis damage only
• Superficial partial thickness (old 2nd degree) - epidermis and upper-level dermis
• Deep partial thickness (old 2nd degree) - epidermis and severe damage to dermis
• Full thickness (old 3rd degree) - epidermis and dermis destroyed
Skin grafts
When medically stable
Full-thickness burns and for large, deep partial-thickness burns
Type of grafts
Autografts: Skin harvested from an unburned area of the patient
Skin substitutes: Can be either
Biologic, such as allografts or xenografts (from cadaver and bovine skin, respectively)
Synthetic, such as Biobrane comprising nylon and silastic
Ejection Fraction (EF)
Percentage of the amount of blood ejected relative to the amount received by the ventricle
Tells us how well the heart is pumping
Normal adult - 60%
Low EF
Systolic dysfunction or failure
Clients present with: low endurance, SOB and LB edema
Congestive Heart Failure
Complex diagnosis resulting from impaired structure and/or function of ventricles affecting heart’s ability to pump.
Heart muscle becomes stretched beyond its ability to contract resulting in fluid in lungs or extremities
Heart pumps forcibly at higher pressure, cardiac walls thicken causing ventricle hypertrophy—making oxygenating heart muscle difficult—may lead to ischemic damage.
75% of individuals with CHF have history of HTN leading to diastolic dysfunction
CHF may begin with acute onset or progress becoming chronic, although many cases are initially asymptomatic.
Symptoms classified stages from mild to severe.
In majority of cases, left-sided heart failure will lead to right-sided dysfunction.
Risk and Predisposing factors of CHF
Risk Factors: Hypertension, eating foods high in fat, sodium, and cholesterol, sedentary lifestyle, emotional stress, obesity
Predisposing Factors: History of: CAD, heart valve disorders, diabetes, thyroid disorders, renal disease
Symptoms and Diagnosis of CHF
Symptoms: Shortness of breath (dyspnea), Shortness of breath while lying down (orthopnea), Fatigue, Muscle weakness, Hepatomegaly: enlargement of the liver, May be nauseated, bloated, or have abdominal pain, Rapid weight gain due to fluid build up within the body, Lower extremity edema, Fluid retention
Diagnosis: Blood tests, Cardiac catheterization, Chest X-ray, EKG, Heart MRI (magnetic resonance imaging), Cardiac computed tomography (CT), Multigated Acquisition Scan (MUGA scan), Stress test.
Medical Management of CHF
Managed with medication and lifestyle changes (ACE inhibitors, ARBs, beta-blockers, diuretics), Surgical interventions may also be indicated (Valve replacements)
Impact on Occupation and OT Role in CHF
Impact on Occupation → Dyspnea (at rest and with exertion [DOE]) and orthopnea (SOB while laying down), Fatigue, Weakness, LE edema, Functional mobility and LE ROM, Skin integrity
OT Role
Monitoring skin integrity (especially with LE edema), Medication management, O2 line management during functional activities, Training in adaptive strategies/equipment for ADLs/IADLs and work/leisure tasks, Energy conservation, Mitigating symptoms associated with adverse effects of medication, Toileting / adaptive strategies to manage urinary incontinence, Reducing fall risk through training on adaptive strategies/equipment to manage dizziness/hypotension
Sleep hygiene-Positioning to manage orthopnea
Lifestyle changes-Healthy meal prep, Home exercise program, stress reduction techniques, Smoking cessation
Peripheral Arterial Disease (PAD) / Peripheral Vascular Disease (PVD)
• Chronic and progressive
• Arteries are narrowed due to buildup of fatty deposits (atherosclerosis)
o The legs or arms – usually the legs – don't get enough blood flow to keep up with demand
o Results in leg pain during ambulation (claudication)
• If not addressed, may lead to amputation
Risk Factors and Predisposing Factors of PAD/PVD
Risk Factors: High BP, High cholesterol, Obesity, Smoking, Sedentary lifestyle
Predisposing Factors: Genetics, Age, History of diabetes, CAD, HIV
Symptoms and Diagnosis of PAD/PVD
Symptoms: Claudication, Muscle pain or cramping in the arms or legs, Cold extremities, Extremity numbness or weakness., Skin color changes on the extremities, Non-healing ulcers
Diagnosis:
Blood tests
Detects high cholesterol, glucose abnormalities
Ankle-brachial index (ABI)
Blood pressure readings are taken in the ankle and arm before and after exercise to compare blood pressure between extremities with activity
Ultrasound
Radiologic imaging to photograph blood flow through the extremities
Doppler ultrasound is a special type of ultrasound used to spot blocked or narrowed arteries
Angiography
Radiologic imaging tests that uses a dye (injected into blood vessel) to check for blockages in the arteries
Medical Management of PAD/PVD
Medication, surgical intervention, lifestyle changes, offloading footwear (for non-healing ulcers on the feet)
Vascular Surgeries: Angioplasty, Bypass grafting, Stent placement, and Atherectomy
Impact on Occupation and OT Role of PAD/PVD
Impact on Occupation:
Pain, Edema, Sensory changes to extremities
Decreased activity tolerance
Foot ulcers > decreased standing tolerance
Claudication > decreased mobility
OT Role:
Health management
Adaptive strategies for safety due to decreased sensation on hands/feet
Skin checks, Foot care/hygiene, Donning/doffing offloading footwear
Pain management
Functional mobility
Training in adaptive strategies/equipment for improved participation in ADLs/IADLs and work/leisure tasks
Lifestyle changes: Home exercise program, Smoking cessation, Stress reduction
Coronary Artery Disease (CAD)
This disease generally arises from atherosclerosis, a buildup of plaque in the coronary arteries
Plaque buildup in the coronary arteries prevents necessary oxygen-rich blood and nutrients from reaching the heart.
This is known as myocardial ischemia
Reduced blood flow to the heart can lead to numerous complications, including: Angina, Myocardial Infarction (Heart attack), Arrhythmias and heart failure
Risk and Predisposing factors of CAD
Risk factors: Smoking, high BP, high cholesterol, obesity, sedentary lifestyle, high stress, use of hormonal birth control
Predisposing Factors
>45 male or >55 female
Genetics
History of:
Anemia.
Autoimmune diseases, including lupus and rheumatoid arthritis.
Chronic kidney disease.
Diabetes.
HIV/AIDS.
Metabolic syndrome.
Sleep apnea.
Endometriosis.
Gestational diabetes, eclampsia or preeclampsia.
Symptoms and Diagnosis of CAD
Symptoms: Chest pain (angina), Nausea & vomiting, Diaphoresis (excessive sweating), Fatigue, Pallor, Coolness of extremities, Shortness of breath (dyspnea)
Diagnosis: Echocardiogram (EKG), Stress test, Cardiac catheterization/angiogram
Medical Management of CAD
Medications
ACE inhibitors, ARBs, beta-blockers, antithrombotic (anti-clotting) agents (aspirin)
Surgical options
Coronary artery bypass graft (CABG) surgery to circumvent blocked vessels.
Or, percutaneous coronary intervention (PCI), (aka: coronary angioplasty) with/without stent placement to open artery.
Impact on Occupation and OT Role of CAD
Impact on Occupation
o Symptoms: dyspnea, fatigue
o Post-operative
Sternal precautions
• Don’t reach both arms overhead.
• Don’t reach both arms out to the side.
• Don’t reach behind your back.
• Don’t lift more than 5 to 8 pounds.
OT Role
o Health management
Monitoring BP
Medication management
o Mitigating symptoms associated with adverse effects of medication
Reducing fall risk through training on adaptive strategies/equipment to manage dizziness/hypotension
o Post-operative
Early mobilization
Training on adaptive strategies/equipment to maintain post-operative sternal precautions
• Energy conservation
o Lifestyle changes
Healthy meal prep
Home exercise program
Stress reduction techniques
Smoking cessation
NSTEMI v. STEMI
NSTEMI – non-ST segment elevation MI
Characterized by a partial coronary blockage, partial-thickness necrosis
STEMI – ST-segment elevation MI
Characterized by a complete coronary blockage, full-thickness necrosis
Vascular Surgeries
Bypass grafting: A healthy blood vessel is taken from another part of the body (commonly the leg)
The new vessel is connected below the blockage, creating a new path for blood flow
Angioplasty: A balloon catheter is inserted into a narrowed artery
The balloon is inflated to squeeze plaque against the artery wall, improving blood flow
Stent placement: A small metal tube is placed in the artery to keep it open
Atherectomy: A device, laser, or blade is used to scrape away plaque
Asthma
inflamed airways, making the airways swollen and sensitive to certain substances, Narrows airways and reduces airflow, Airways react with irritants, causing muscles to constrict, Narrows airways and reduces airflow, Increase in mucus production, Narrows airways and reduces airflow
• Pediatric: Symptoms are irregular, Higher sensitivity to allergens, Increased likelihood of asthma attack, Symptoms may disappear during puberty
• Adult: Persistent symptoms, Require regular symptom management, Chronic
COPD
Characterized by airflow obstruction impacting gas exchange causing dyspnea and limited reserve lung capacity, Umbrella term for emphysema, chronic bronchitis, and obstructive bronchiolitis, It is Progressive
• Anti-inflammatory response that results in: A lack of elastic recoil in airways and alveoli, The walls between alveoli being destroyed, The walls of airways becoming thick and inflamed, The airways making more mucus than usual and becoming clogged, All cause less air to flow in and out of the airway
• Hypercapnia = buildup of carbon dioxide in your bloodstream, Affects people who have chronic obstructive pulmonary disease (COPD), air cannot leave the lungs during expiration and becomes trapped, leading to dyspnea, exercise intolerance, and reduced ability to engage in physical activities
Dialysis
Process of removing waste from the blood, used when kidneys cannot effectively perform these functions (chronic kidney disease)
Out of bed activity is contraindicated during dialysis treatment
Hemodialysis: Administered through vascular access port, usually an arm or leg. 2 port types: Arteriovenous (AV) fistula: Created under the skin of the extremity or an AV graft: Graft is created using plastic tubing where a loop connects the artery and vein
Patient is connected to HD machine - blood passes out of the body into the machine where it is cleansed and returned to the body; can take between 4-5 hours
Peritoneal dialysis: Catheter is surgically inserted into the abdomen, through which a solution (called dialysate) is infused to absorb body wastes; session can take between 4-6 hours, can be performed at home
Continuous renal replacement therapy: Specialized for acute kidney failure, Used with critically ill patients, Administered through central venous catheter (CVC), which is connected to CRRT machine – blood is removed, cleansed, and returned to the body; may be operated 24 hours/day, depending on patient's needs
OT Role in Dialysis Patients
Health management, Medication management, Managing urinary catheters during ADLs, mobility, Mitigating symptoms associated with adverse effects of medication, Toileting / adaptive strategies to manage urinary incontinence, Energy conservation strategies (especially during dialysis days), Reducing fall risk through training on adaptive strategies/equipment to manage dizziness/hypotension, Lifestyle changes, Meal prep with dietary restrictions, Fluid restrictions, Home exercise program
Chronic Liver Disease
Refers to conditions pertaining to liver damage
Symptoms: Yellowing of your skin or the whites of eyes (jaundice), Edema and abdominal ascites, Dark-colored urine, Digestive difficulties, especially with fats, Weakness and muscle loss, Mild brain impairment (hepatic encephalopathy), Associated with buildup of ammonia in the blood, Pruritus (itchy skin, but with no visible rash), Fatigue, Nausea or loss of appetite
Hepatitis → Fibrosis → Cirrhosis → End-stage liver disease
T1D vs. T2D
Type I diabetes—Body doesn’t produce insulin, 10% cases
Type II diabetes—Body doesn’t produce insulin or doesn’t use properly, leading to hyperglycemia— 90% cases
Medical Management of Diabetes
Daily insulin therapy: Continuous blood glucose monitoring + insulin therapy (daily injections via pens/syringes or an insulin pump to provide both basal (background) and prandial (mealtime) coverage), Combination of lifestyle changes and medications (Metformin)
Impact on Occupation and OT Role in Diabetes
Impact on occupation: Fatigue, Possible visual changes (diabetic retinopathy), Sensory changes (neuropathy), Delayed healing of wounds, Especially on the feet, Increased pain during functional mobility, ADLs/IADLs and work/leisure tasks, Risk of infection
OT Role: Medication management, Blood glucose testing and insulin management, Skin checks/foot checks, Hygiene/bathing, Mitigating symptoms associated with uncontrolled diabetes, Visual strategy training, Diabetic retinopathy Adaptive strategies for sensory loss Neuropathy, Lifestyle changes like healthy meal prep, exercise program, stress reduction, and smoking cessation
Cancer
a group of diseases where (a) abnormal cells divide without control, (b) invade nearby tissues, and (c) travel (via blood & lymph) to other body parts. Classified by body location and tissue type at origination
Metastases
named for originating locations— then spread (e.g., breast cancer with metastasis to bones).
Common types of cancer seen in OT → symptoms and impact on occupation
Breast cancer: Weakness, fatigue, body-image issues, pain, lymphedema, limited range of motion, brachial plexus injury, cognitive inefficiencies
Lung cancer: Fatigue, dyspnea, weakness, limited ROM and endurance
Brain cancer: Cognitive problems, impaired vision and balance, decreased sensation, dysphasia, hemiparesis, impaired coordination, personality changes
Head and neck cancer: Limited cervical ROM, shoulder dysfunction, loss of scapular stability, difficulty swallowing, speech problems, stigma associated with disfigurement
Medical Management of Cancer
Chemotherapy: medicines or drugs that can be used to contain or slow tumor growth or kill cancer cells
Radiation: using high energy particles or wavelengths to kill the cancerous cells and shrink tumors
Immunotherapy: substances made from living organisms to treat cancer