Cancer Genes

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7 Terms

1
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HER2/neu

Human epidermal growth factor receptor 2

Synonymous w/ERBB2

Breast Cancer

Gene Product: Receptor tyrosine kinase

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EGFR

Epidermal growth factor receptor

Lung cancer

Gene Product: Receptor tyrosine kinase

3
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RAS

KRAS - Kirsten rat sarcoma viral oncogene homolog

NRAS - Neuroblastoma ras

Lung cancer

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MET

Lung cancer

Gene Product: Receptor tyrosine kinase

5
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ALK

Anaplastic lymphoma kinase

Hematologic malignancies & neuroblastoma

Gene Product: Receptor tyrosine kinase

6
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ROS1

Nonsmall cell lung cancer, Glioblastoma, & Cholangiocarcinomas

Gene Product: Receptor tyrosine kinase

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NTRK

Neurotrophic tropomyosin receptor kinases

Many cancers

Gene Product: Transmembrane receptor tyrosine kinases