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describe proteins
contain carbon, hydrogen, oxygen, and nitrogen. made of amino acids
compare essential to nonessential amino acids
there are nine essential amino acids that you get from the diet
list 3 essential amino acids
leucine, lysine, valine
describe conditionally essential amino acids
when essential is not available, it makes these nonessential
describe peptide bond
joins amino acids together
dipeptide
2 amino acids
tripeptide
3 amino acids
oligopeptide
4-10 amino acids
polypeptide
11+ amino acids
denaturation
destorys proteins 3d structure. heat and acid can cause it. ex: egg
define acid
donates H ions
define base
accepts H ions
define pH
measure of H ion concentration
define buffer
keeps stable pH
describe proteins as acid/base regulators
Proteins acts as buffers because one part of amino acids can donate H ions and the other part can accept H ions
define collagen
tissue health
define enzymes
catalysts
define antibodies
defends body against disease
define antigens
what antibody recognizes
define hormones
insulin
define cell membrane proteins
receptors like insulin receptors
define fibrin
form bulk of a blood clot
define hemoglobin
iron containing protein in blood
define transferrin
transfer iron from liver to bone marrow
define opsin
part of photoreceptors in eye needed for vision
define neurotransmitter
allow nerves to communicate
define complete protein
protein that has all of the essential amino acids (ALL animal proteins are complete – only some plant proteins like soy are complete)
define incomplete protein
doesn’t have all essential amino acids
define biological value
a standard used to compare other proteins (egg has a 100% value)
define PEM
insufficient intake of protein, energy, or both. Prevalent form of malnutrition. Impact is poor growth for children
define marasmus
chronic PEM. Deprivation of protein, energy (calories), vitamins, and minerals. Impaired growth, wasting of muscle, impaired brain development
define kwashiorkor
acute PEM. A severe protein deficiency (energy, vitamins, mineral not deficient, but child not getting enough or high-quality protein). Develops rapidly
define dysentry
severe diarrhea
define aflatoxin
toxin in mold that inhibits protein synthesis found in grains and nuts
define edema
swelling caused by excess fluid in body’s tissues
Define N balance (positive if retaining protein and negative if losing)
means synthesis= breakdown. Positive: synthesis > breakdown (ex: growing kids). Negative: breakdown > synthesis (ex: starvation)
Know the recommended protein intake
10%-35% of daily energy intake
Discuss problems with high protein diets and amino acid supplements
Heart disease, cancer, kidney disease (excess urea formation), osteoporosis
Describe tofu
complete plant protein (soy)
define anabolism
synthetic reactions or building reactions
define catabolism
breakdown reactions or decomposition
review cell parts and functions
DNA -> RNA (transcription) -> protein (translation). Ribosomes are the site of protein synthesis. Golgi packages and ships proteins to destination. Mitochondria is where ATP is made.
describe enzymes
proteins that makes reactions occur
describe coenzymes
help enzymes
____vitamin serves as ___ in energy metabolism
B; coenzymes
list 3 pathways involved in breakdown of glucose
glycolysis
krebs
et
define glycoloysis
start glucose turned into pyruvate, form +2ATP. can take place in presence or absence of oxygen. pyruvate changed to AcetylCoA
define krebs
starts AcetylCoA. requires oxygen. byproducts are CO2, 2ATP, NADH, & FADH
define et
most atp made here
define aerobic respiration
breakdown of glucose in the presence of oxygen to form large amounts of ATP
define anerobic transportation
breakdown of glucose in the absence of oxygen to form a few ATP and a lot of lactic acid
describe Cori cycle
Lactic acid gets converted back to glucose in the liver
Describe fat metabolism
Fatty acids get converted to Acetyl CoA, so they enter at Krebs Cycle
amino acid metabolism includes…
deamination and urea formation
deamination
amino group removed – carbon backbone used for ATP
urea formation
deamination leads to urea. Urea is a protein metabolism waste product normally found in urine
Describe the production of ketones
When carb intake is low, Acetyl CoA builds up and gets turned into ketone bodies (used as an alternate fuel source)
Describe alcohol
A drug considered a CNS depressant
Describe the absorption and metabolism of alcohol and its effects on the liver
Alcohol is quickly absorbed unless there is food present in stomach. Alcohol dehydrogenase is an enzyme in the liver that converts alcohol to a least toxic form
Describe 3 negative effects of alcohol discussed in class
Interfere with judgement, slows reaction time, addiction, damage liver, fetal alcohol syndrome (if mom is pregnant).
Know the number of calories in a pound of fat
1lb body fat = 3,500 calories
define hunger
physiological NEED to eat
define appetite
the desire to eat
define amylin and cholecystokinin
hormones that promote satiety (fullness)
define gherlin
hormone that stimulates hunger and food intake
define BMR
basal metabolic rate
define basal metabolism
energy (calories) burned just to stay alive
List factors that affect basal metabolic rate
Caffeine, gender, nicotine, hypothyroidism.
Be able to estimate energy requirements
diet analysis
Define BMI
Index of a person’s weight in relation to height. Used to determine if person is underweight, healthy, overweight, or obese. Does not take in to account one’s body composition. BMI greater than or equal to 30 is obese.
describe some problems with being overweight
Type 2 diabetes, hypertension, heart attack
What is the minimum recommended body fat percentage
5% men and 15% women
List some problems with being underweight
Women: fertility problems, infants unhealthy, can’t fight cancer
Discuss anorexia nervosa
Distorted body image, refusal to eat, compulsive exercise habits, increased risk for higher achievers
Discuss bulimia
Binge eating followed by purging (vomiting or laxatives), weight fluctuations
Describe some characteristics of fat cells
Grow in # until teens and then enlarge. After fat in skin fills, fat will be deposited in and around organs
Describe the relationship between lipoprotein lipase and weight gain or loss
Women have higher levels of this enzyme in hips and thighs. Men have higher levels in abdomen
Describe Prader Willi Syndrome
Genetic condition, constantly hungry, intellectually impaired
Compare white fat and brown fat
White is more for storage. Brown is used for heat (higher in infants and lower in adults)
Briefly describe some causes of overweight and obesity
Genetics, overeating, physical inactivity
define cellulite
visible fat under the skin. older we are, more visible
define bariatrics
field of medicine treating obesity
drug for treating obesity
subutramine, meridia - appetite suppressant
___ bypass or banding is used to treat obesity
gastric
define liposuction
surgery to break up fat and then remove it
List some strategies for weight loss
500 calorie deficiency/day should produce weight loss of 1lb/week. Choose nutrient dense foods, choose complex carbs (legumes, fruits, vegs, and whole grains). Limit high fat foods, portion control.
list some strategies for gaining weight
Pick highest calorie foods (milkshake, avocados, juice)
define diuretics
increase urine output, but only cause water weight loss, dangerous
define vitamins
organic molecules needed in small amounts for good health
water soluble vitamins are…
readily excreted in the urine and you are less likely to reach toxic levels because of that
fat soluble vitamins are…
stored in fatty tissue and carry higher risk for toxicity symptoms
define bioavailability
how well a nutrient/drug can be absorbed in blood stream
B vitamins role is to
help your body turn carbs, fats, and proteins to fuel
thiamin function
energy metabolism and keeps nerves healthy
thiamin source
pork and enriched grain products
define Wernicke-Korsakoff syndrome
condition of severe thiamin deficiency in chronic alcohol abusers
___ decreases absorption of thiamin
alcohol
define Beriberi
condition of prolonged thiamin deficiency that causes weakness or damage to nervous system, heart, and muscles
riboflavin functions
energy metabolism and important for healthy tissue and membranes
define Ariboflavinosis
inflammation of membranes when deficient in riboflavin