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What is a neurone
A specialised nerve cell that transmits electrical impulses around the body
What is the role of the cell body
It contains the nucleus and genetic material allowing the cell to function and it’s the site of neurotransmitter production
What is the structure and function of the dendrons
they are extensions of the cell body which divide into dendrites and transmit electrical impulses towards the cell body
What is the structure and function of axons
Nerve fibres which transmit electrical impulses away from the cell body towards the axon terminals
What is the role of a sensory neuron
To transmit electrical impulses from sensory receptors to relay neurons/CNS
What is the role of a motor neurone
To transmit electrical impulses from relay neurons in the CNS to effectors (muscles/glands)
What is the role of a relay neurone
To transmit electrical impulses between sensory and motor neurones
Where is the cell body located in a sensory neurone
Between the dendrites
Where is the cell body located in a motor neurone
Between the dendron and the axon
What is the structure of a relay neurone
An intermediate neurone with very short axons and dendrites
What is the sequence of a reflex arc
Stimuli, receptor, sensory neurone, relay neurone, motor neurone, effector and response
What is myelin sheathing composed of
Phospholipid bilayers
Where are layers of myelin sheaths produced
Schwann cells
What are the gaps between myelin sheaths called
Nodes of Ranvier
What is it called when the impulse jumps between nodes of ranvier
Saltatory conduction
why are some neurones covered in myelin sheath
It speeds up the rate of neuron transmission and allows saltatory conduction
How does cell signalling occur
A cell releases a chemical which acts on a target cell
What is an example of local cell signalling
Cell signalling between synapses
What is an example of cell signalling travelling across large distances
Using hormones
What is homeostasis
Maintaining a relatively constant internal environment
What is an example of external environmental changes
Temperature/humidity/light intensity
What is an example of internal environmental changes
Blood glucose concentration/water potential/temperature/cell pH
What occurs in people who have multiple sclerosis
An autoimmune response causes the myelin sheath to thin/break down leading to the breakdown of the axon, affecting the speed of neuronal transmission
What is a mechanoreceptor
A sensory receptor sensitive to pressure and movement
What is a chemoreceptor
A sensory receptor sensitive to chemicals
What is a thermoreceptor
A sensory receptor sensitive to temperature/heat
What is a photoreceptor
A sensory receptor sensitive to light
What is an example of a key mechanoreceptor
The Pacinian corpuscle
What is a transducer
Generator potentials that convert stimuli to electrical impulses
What occurs in the Pacinian corpuscle at normal resting state
The stretch mediated sodium ion channels are closed/maintaining resting potential/the concentration of sodium ions is higher outside the neurone
What occurs in the Pacinian Corpuscle when pressure is applied
The neurone membrane stretches as the corpuscle changes shape leading to the stretch mediated sodium ion channels to open
What happens when the stretch mediated sodium ion channels in the Pacinian corpuscle open
The sodium ions diffuse into the sensory neurone through the stretch mediated ion channels along the electrochemical gradient causing the membrane to become depolarised generating an action potential along the sensory neurone
Where are Parcinian corpuscle cells commonly found
In the fingertips/skin/joints/feet