QAS Benzatropine DTP

Vocabulary flashcards covering the pharmacology, clinical indications, contraindications, dosages, precautions, and administration routes of benzatropine according to Queensland Ambulance Service clinical guidelines.

Drug Class

Antichlolinergic.

Pharmacology

Synthesised from components of the atropine and diphenhydramine drug molecules; possesses strong anticholinergic and antihistamine properties whilst inhibiting dopamine re-uptake to restore balance between acetylcholine and dopamine in the central nervous system, thereby alleviating acute dystonias.

Metabolism

Hepatic.

Indications

Acute dystonic reaction.

Contraindications

1. Allergy and/or Adverse Drug Reaction

2. Tardive Dyskinesia

3. Patients <3 years old

Precautions

1. Sedative effects of other drugs may be enhanced

2. Use in children <12 years old

Side Effects

1. Dilated pupils

2. Dry mouth

3. Nausea and/or vomiting

4. Tachycardia

5. Toxic psychosis including confusion and visual hallucinations

6. Urinary retention and/or dysuria.

Presentation

Vial, 2mg/2ml of benzatropine.

Pharmacokinetics

Onset (IV): 1-2 minutes

Duration (IV): 1-2 hours

Half-life: roughly 16 hours

Benzatropine (Schedule)

S4 (Restricted drugs).

Adult Dose

IM/IV: 1-2mg, single dose only.

Paediatric Dose

IM/IV: 20microg/kg, single dose only.

(QAS officers are NOT authorised to administer to paediatric patients <3 years old)