Module 6 - FPB

A) Health

It is defined as the state of complete physical, mental and social well-being and not merely the absence of disease or infirmity.
A. Health
B. Wellness
C. Fitness
D. Vigour

D) Coccus

These are sphere-shaped bacteria.
A. Spirillum
B. Bacillus
C. Sporus
D. Coccus

B) R Factor

A bacterial plasmid carrying genes that determine resistance to antibiotics.
A. F plasmid
B. R Factor
C. A plasmid
D. M Factor

B) Diplococci

Cocci arranged in pairs.
A. Staphylococci
B. Diplococci
C. Streptococci
D. Sarcinacocci

A) F factor

A plasmid found in the donor cell in bacterial conjugation.
A. F factor
B. B factor
C. C factor
D. P factor

C) Conjugation

It is the process of transfer of genetic material from one bacterial cell to another involving cell-to-cell contact.
A. Transduction
B. Reception
C. Conjugation
D. Transposition

A) Escherichia coli

Montezuma's Revenge is caused by which of the following:
A. Escherichia coli
B. Corynebacterium difficile
C. Clostridium tetani
D. Enterobacter aerogenes

B) Mycoplasma

Walking pneumonia is caused by:
A. Chlamydophila
B. Mycoplasma
C. Haemophilus
D. Pneumococcus

C) Bacillus cereus

Causes gastroenteritis arising from consuming reheated fried rice
A. Bacillus subtilis
B. Clostridium botulinum
C. Bacillus cereus
D. Clostridium perfringens

C) Lowenstein-Jensen medium

This is the growth medium used in culturing Mycobacterium tuberculosis.
A. Thayer Martin agar medium
B. Hoyle's agar medium
C. Lowenstein-Jensen medium
D. Loeffler's medium

D) Virion

A complete and mature viral particle
A. Viroid
B. Viroin
C. Viriod
D. Virion

B) Cryophile

A cold-loving microbe
A. Mesoophile
B. Cryophile
C. Thermophile
D. Psychophile

C) Aerotolerant Anaerobes

Which of the following does not use oxygen but is not affected by its presence?
A. Aerobes
B. Microaerophiles
C. Aerotolerant Anaerobes
D. Facultative Anaerobes

C) Halophiles

These organisms grow optimally in highly salty environments.
A. Cryophiles
B. Salinophiles
C. Halophiles
D. Sodiophiles

B) Microaerophiles

Which of the following grow optimally in environments with lesser oxygen levels than normally found in air?
A. Aerobes
B. Microaerophiles
C. Aerotolerant Anaerobes
D. Facultative Anaerobes

D) Chitin

Cell walls of Fungi are made of this compound
A. N-Acetylmuramic Acid
B. Ergosterol
C. Cellulose
D. Chitin

B) Ergosterol

Cell membranes of Fungi are made of this compound
A. N-Acetylmuramic Acid
B. Ergosterol
C. Cellulose
D. Chitin

D) Paracoccidioides braziliensis

Causative Agent of South American Blastomycosis
A. Blastomyces dermatitidis
B. Histoplasma capsulatum
C. Candida albicans
D. Paracoccidioides braziliensis

A) Histoplasmosis

Spelunker's Disease
A. Histoplasmosis
B. Chromomycosis
C. Coccidiodimycoses
D. Sporotrichosis

B) Tinea cruris

Jock Itch
A. Tinea corporis
B. Tinea cruris
C. Tinea pedis
D. Tinea versicolor

A) Sporothrix schenkii

Causative agent of Rose Gardener's Disease
A. Sporothrix schenkii
B. Cryptococcus neoformans
C. Aspergillus flavus
D. Exophiala wernickii

C) Streptomyces nodosus

Amphotericin is derived from which of the following:
A. Streptomyces noursei
B. Streptomyces orientalis
C. Streptomyces nodosus
D. Streptomyces cerevisiae

A) Echinocandins

Inhibition of β-D glucan synthase
A. Echinocandins
B. Azole Antifungals
C. Polyene Antifungals
D. Terbinafine

C) Fluconazole

This antifungal is used in meningitis arising as complication from various mycoses.
A. Amphotericin
B. Itraconazole
C. Fluconazole
D. Ketoconazole

B) Mycoplasma

When isolates from throat swabs and sputum grow on horse serum and yeast extract medium, they form characteristic "fried egg" colonies.
A. Mycobacteria
B. Mycoplasma
C. Mycofungus
D. Mycococcus

B) Prions

Infectious particles that are smaller than viruses that cause transmissible spongiform encephalopathies (TSE)
A. Virion
B. Prions
C. Exons
D. Viroid

B) Cytomegalovirus (CMV)

Most common cause of genetic/congenital anomalies in the USA
A. Hepadnavirus
B. Cytomegalovirus (CMV)
C. Epstein-Barr virus (EBV)
D. Poxvirus

D) Poxvirus

All DNA viruses are icosahedral except:
A. Parvovirus
B. Papovavirus
C. Papovirus
D. Poxvirus

C) Hepatitis A

Which of the following does not cross the placenta?
A. Rubella
B. Syphilis
C. Hepatitis A
D. CMV

A) Parvovirus B19

Causative Agent of 5th Disease/Erythema Infectiosum
A. Parvovirus B19
B. Papovavirus B19
C. Paramyxovirus B19
D. Papillomavirus B19

D) Interferon

A special group of cytokines with antiviral properties.
A. Macrophage
B. Interleukin
C. Natural Killer Cells
D. Interferon

B) IgM

The first class of immunoglobulins to appear after exposure to an antigen
A. IgA
B. IgM
C. IgE
D. IgD

C) B cells

For humoral, antibody-driven and adaptive immunity
A. T cells
B. NK cells
C. B cells
D. CD4 cells

B) Thymus

Where T cells mature
A. Thyroid
B. Thymus
C. Bone Marrow
D. Spleen

D) Plasma Cell

Produces large volumes of antibodies
A. Megakaryocytes
B. Lymphoblasts
C. Myeloblasts
D. Plasma Cell

B) Acquired, Passive Immunity

Immunity achieved by the administration of immunoglobulins, antitoxin and antisera
A. Acquired, Active Immunity
B. Acquired, Passive Immunity
C. Natural, Active Immunity
D. Natural, Passive Immunity

B) Interleukin

A chemical that causes T cell proliferation.
A. Macrophage
B. Interleukin
C. Natural Killer Cells
D. Interferon

C) NK Cells

These type of cells distinguish infected cells and tumors from normal and uninfected cells by recognizing changes of a surface molecule called MHC (major histocompatibility complex) class I.
A. T Cells
B. B Cells
C. NK Cells
D. CD Cells

D) Type IV

Mantoux Test features what type of hypersensitivity reaction
A. Type I
B. Type II
C. Type III
D. Type IV

C) Opsonization

Antibodies employ certain molecules to coat microbes and promote their ingestion by phagocytes. This process is known as
A. Phagocytosis
B. Syneresis
C. Opsonization
D. Limerence

A) Directly Observed Therapy, Short-Course

DOTS
A. Directly Observed Therapy, Short-Course
B. Directly Observational Treatment, Short-Course
C. Directly Observed Treatment, Short-Term
D. Directly Observational Therapy, Short-Term

B) Marasmus

Protein-Energy Malnutrition Characterized by Low Calorie and Low Protein Intake
A. Kwashiorkor
B. Marasmus
C. Anorexia
D. Bulimia

C) Ergonomics

The science of designing the job to fit the worker, rather than physically forcing the worker's body to fit the job.
A. Occupational Health
B. Safety Science
C. Ergonomics
D. Plyometrics

B) Garantisadong Pambata

DOH Health Program formulated to provide comprehensive and integrated package of services and communication on health, nutrition and environment for children available everyday at various settings
A. Essential Newborn Care
B. Garantisadong Pambata
C. Infant and Young Child Feeding
D. Food Fortification Program

C) Vitamin C

Fortification of food products is mandated by DOH's Sangkap Pinoy Seal Program/Food Fortification program. The following micronutrients are added except:
A. Iron
B. Iodine
C. Vitamin C
D. Vitamin A

A) MMR

The first dose of this vaccine is usually administered at age 12 through 15 months except in cases of outbreak in which it may be given in as early as 6 months of age.
A. MMR
B. Hepatitis B
C. DTP
D. HPV

B) Enlightenment

The 4 Es of the DOH Violence and Injury Prevention Program include the following except:
A. Education
B. Enlightenment
C. Economic
D. Enforcement

A) Sec. Juan Flavier

Started the "Let's DOH it" campaign of the DOH
A. Sec. Juan Flavier
B. Sec. Enrique Ona
C. Sec. Jaime Galvez-Tan
D. Sec. Alberto Romualdez

B) Quality Assurance

The sum total of the organized activities performed with the intent to ensure that all APIs are of the quality required for their intended use.
A. Quality Management System
B. Quality Assurance
C. Quality Control
D. Quality

C) Current Good Manufacturing Practice

cGMP
A. Correct Good Manufacturing Practice
B. Correct Good Manufacturing Policy
C. Current Good Manufacturing Practice
D. Current Good Manufacturing Policy

A) Sieving

Official USP Method for Particle Size Determination
A. Sieving
B. Optical Microscopy
C. Particle Volume Measurement
D. Sedimentation Method

B) Friability

The ability to withstand the rigors of packaging and transport
A. Thickness
B. Friability
C. Disintegration
D. Hardness

D) Disintegration

Basket Rack Assembly is utilized in which FPQC test?
A. Dissolution
B. Weight Variation
C. Content Uniformity
D. Disintegration

D) 37° ± 0.5

Temperature Specification for Dissolution Testing
A. 36° ± 2
B. 36° ± 0.5
C. 37° ± 2
D. 37° ± 0.5

D) Coulter Tester

Hardness Testing is done with the following equipment except
A. Stokes-Monsanto Tester
B. Strong-Cobb Arner Tester
C. Pfizer Hardness Tester
D. Coulter Tester

C) Fair

A powder with an angle of repose of 37° is deemed to have what type of flow?
A. Excellent
B. Very Poor
C. Fair
D. Gentle

B) 0.8%

Friability Limit for New Formulations
A. 0.5%
B. 0.8%
C. 1.0%
D. 1.2%

B) Buccal Tablet

Which of the following will have the longest time limit to disintegrate according to the USP?
A. Plain Uncoated Tablet
B. Buccal Tablet
C. Sublingual Tablet
D. Enteric Coated Tablet

B) 5%

Allowable % Difference in Weight Variation for a 325 mg tablet
A. 2.5%
B. 5%
C. 7.5%
D. 10%

C) Paddle Over Disk

USP Dissolution Apparatus Type V for Transdermal Drug Products
A. Reciprocating Basket
B. Rotating Cylinder
C. Paddle Over Disk
D. Flow Through Cell

A) o/w

When subjected to the dye solubility test, the sample turned green. The test sample is:
A. o/w
B. w/o
C. o/w/o
D. None of the above

B) Minimum Fill

Applicable for articles such as creams, gels, lotions that are packaged in containers in which the labelled content is not more than150 g or 150 mL.
A. Deliverable Volume
B. Minimum Fill
C. Content Uniformity
D. Net Volume/Content

B) Type II

Water Attack Test is done on which type of glass?
A. Type I
B. Type II
C. Type III
D. Type NP

D) None

The unit of Relative Viscosity
A. Pa-s
B. Poise
C. Stokes
D. None

D) NOTA

According to the USP, the parts of a "container" include the following, EXCEPT:
A. Container itself
B. Liner
C. Container Closure
D. NOTA

A) 0.8

Sedimentation Volume of a suspension with a Vf of 80 mL and Vi of 100 mL
A. 0.8
B. 1.25
C. 80
D. 125

D) 250 mL

Products labeled to contain not more than this volume may be subjected to Deliverable Volume testing
A. 100 mL
B. 150 mL
C. 200 mL
D. 250 mL

C) 30

In Torque Testing, how many times should the container be closed and opened?
A. 20
B. 25
C. 30
D. 50

B) CoCl2

Also known as Lover's Ink, used in determining the type of emulsion
A. CuCl2
B. CoCl2
C. Fe4[Fe(CN)6]3
D. Fe3[Fe(CN)6]4

D) 0.1 mcg

The USP limit for Arsenic in glass.
A. 0.05 mcg
B. 0.5 mcg
C. 0.01 mcg
D. 0.1 mcg

B) Standardization

Process of determining the exact concentration of a solution
A. Titrimetry
B. Standardization
C. Complexometry
D. Molarity

D) NOTA

Moles of solute in 1 kg of solution
A. Molarity
B. Molality
C. Normality
D. NOTA

D) Accuracy

Closeness of a measurement to the true value
A. Precision
B. Frequency
C. Truth
D. Accuracy

D) Equivalence Point

Theoretical point in which equivalent amount of analyte and titrant have reacted.
A. Endpoint
B. Stoichiometric Point
C. Standardization Point
D. Equivalence Point

D) Titer

Amount of substance chemically equivalent to 1 mL of standard solution.
A. Concentration
B. Titrand
C. Titrant
D. Titer

A) Ultimate Assay

Assay of Morphine Content of Theobroma cacao can be considered what type of analysis based on extent
A. Ultimate Assay
B. Proximate Assay
C. Semi-Micro Assay
D. Macro Assay

A) Yellow

The color arising when Phenol Red is added to an acidic solution
A. Yellow
B. Fuchsia
C. Red
D. Orange

D) Sparingly Soluble

1 part of solute dissolves in 35 mL of solvent
A. Very Soluble
B. Freely Soluble
C. Soluble
D. Sparingly Soluble

C) Semi-Micro Analysis

Type of analysis utilizing 10-100 mg of sample
A. Ultramicro Analysis
B. Micro Analysis
C. Semi-Micro Analysis
D. Macro Analysis

A) L-Cysteine

Fluid Thioglycollate Medium is composed of the following EXCEPT
A. L-Cysteine
B. Pancreatic Digest of Casein
C. Sodium Chloride
D. Sodium Thioglycollate

A) 0.73

What is the gravimetric factor used in the gravimetric analysis of BaCl2 via precipitation with AgNO3? (MW of BaCl2: 208.23 g/mol), MW of AgCl2: 143.32 g/mol)
A. 0.73
B. 1.45
C. 1.38
D. 0.69

C) Dark Blue to Colorless

The endpoint of iodometry when starch TS is used as indicator
A. Colorless to Dark Blue
B. Colorless to Violet
C. Dark Blue to Colorless
D. Violet to Colorless

D) Residual Alkalimetry

Assay of Aspirin Capsules is what type of titration
A. Direct Acidimetry
B. Residual Acidimetry
C. Direct Alkalimetry
D. Residual Alkalimetry

C) 400 – 700 nm

Visible Region in the Electromagnetic Spectrum (nm)
A. 0.01 – 0.1 nm
B. 1 – 400 nm
C. 400 – 700 nm
D. 700 – 10,000 nm

B) Retardation Factor

In TLC/Planar Chromatography, it is the distance travelled by solute over the distance travelled by the solvent
A. Retention Factor
B. Retardation Factor
C. Resolution
D. A and B are the same
E. B and C are the same

E) AOTA

Methods of detection used in TLC EXCEPT
A. Use of Iodine
B. Use of Spray Reagents
C. Use of UV light
D. Use of Potassium Permanganate
E. AOTA

D) Flame Ionization Detector

According to USP

B) Bathochromic Shift

Shift that happens when an auxochrome is present
A. Hypochromic Shift
B. Bathochromic Shift
C. Hyperchromic Shift
D. Hypsochromic Shift

B) UPLC

Chromatographic Analysis involving pressure reaching 100 MPa and a column with particle size of 1.2 mcm and column length of 5 cm
A. HPLC
B. UPLC
C. GC
D. TLC

C) Martin and Synge

1952 Nobel Prize for Chemistry was awarded to him/them for the invention of Partition Chromatography
A. Tswett
B. Beer and Lambert
C. Martin and Synge
D. Coblentz

B) Cat

The animal used in testing Glucagon
A. Rabbit
B. Cat
C. Rachitic Rat
D. Chicken

C) Vitamin E

The vitamin assayed using Gas Chromatography
A. Vitamin A
B. Vitamin D
C. Vitamin E
D. Vitamin K

B) Pseudomonas aeruginosa

Microorganism used in microbial assay of Carbenicillin
A. Saccharomyces cerevisiae
B. Pseudomonas aeruginosa
C. Staphylococcus epidermidis
D. Bacillus subtilis

C) Cylinder Plate Method

Kirby Bauer Method is also known as
A. Method B (USP Microbial Assay of Antibiotics)
B. Tube Dilution Method
C. Cylinder Plate Method
D. Disk Inhibition Method

D) Lactabacillus plantarum

Bioassay of Niacin involves the use of
A. Lactobacillus shirota
B. Lactobacillus caseii
C. Lactobacillus protectus
D. Lactabacillus plantarum

B) As

Limit Test for this metal involves spectrophotometry using a 535 to 540 nm filter
A. Ca
B. As
C. Na
D. Cl

B) 530 nm

The wavelength of the filter used in Turbidimetric Method of Microbial Assay of Antibiotics
A. 490 nm
B. 530 nm
C. 650 nm
D. 700 nm

A) In Vivo Biological Reactivity Tests

Official USP tests designed to determine the biological response of animals to elastomerics, plastics and other polymeric material with direct or indirect patient contact, or by the injection of specific extracts prepared from the material under test.
A. In Vivo Biological Reactivity Tests
B. Container Permeation Tests
C. In Vitro Biological Reactivity Tests
D. Parenteral Permeation Tests

D) IV

To what Climatic Zone does the Philippines belong to?
A. I
B. II
C. III
D. IV

C) Method III

According to the USP, water content of powdered and unpowdered drugs are determined by this method
A. Method I
B. Method II
C. Method III
D. Method IV