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behavioral neuroscience
exploring that different brain pathways lead to different behaviors (what is studied? common behaviors within and between species)
active areas of research (behavioral neuroscience)
feeding, sex, aggression, day/night rhythms, sleep
explorations of behavior
-object descriptions
-studying the anatomy of brain pathways
-studying neurochemicals used in pathways (includes hormones)
-how pathways develop (genetics included) and evolve
Sexually same organs
- gonads
- kidney
- ureter
- mullerian duct
- wolfian duct
what is a gonad?
primary reproductive organ that produces either testes or ovaries
what is a mullerian duct?
the pair of tubes that develop into female reproductive organs
what is a wolfian duct?
the pair of tubes that develop into male reproductive organs
anterior commissure (AC)
a bundle of axons that connects the left and right cerebral hemispheres
third ventricle (V)
slit-like cavity that produces, stores, and circulates cerebrospinal fluid
what regions are in the hypothalamus that participate in sexual behavior?
sexually dimorphic nucleus (male), ventral medial (female)
what happened when a rat was castrated?
copulatory scores (sexual behavior) decreased in all rats regardless of sex drive
what regulated sexual behavior? (rat's castration)
both low and high doses regulated sexual behavior
Male sexual behaviors pathway (rats)
1) female pheromone
2) vomeral nasal (accessory nasal system)
3) medial amygdala
4) medial pre optic area (mPOA) -> houses sexually dimorphic nucleus
5) ventral midbrain
6) brainstem
7) spinal cord
8) stimuli (mechanical energy)
9) ejaculation
female pheromone (function)
needed to jumpstart reaction, testosterone depolarizes but not to threshold
vomeral nasal [accessory nasal system] (function)
not active in humans, detects pheromones
medial amygdala (function)
receives direct and indirect inputs from accessory and main olfactory bulbs, processes pheromones
medial pre optic area [mPOA] (function)
in anterior hypothalamus, central role in regulating reproduction, and social behaviors
sexually dimorphic nucleus
regulates reproductive and sex-typical behaviors
ventral midbrain
critical hub for motor control, movement coordination, and reward pathways
female sexual behavior pathway (rats)
1) male pheromones + high levels of estrogen
2) ventromedial hypothalamus
3) periaqueductal gray
4) medullary reticular formation
5) reticulospinal tract
6) lordosis reflex
7) stimulus -> mechanical energy around genitalia
ventromedial hypothalamus (function)
drives female sexual behavior, triggering the lordosis reflex
periaqueductal gray (function)
located in midbrain, executes lordosis reflex
medullary reticular formation (function)
stimulates deep back and axial muscle contractions
reticulospinal tract (function)
translates sexual motivation and sensory arousal into coordinated physical reflexes
lordosis reflex
hormone-driven mating posture typically seen in non-primate animals
paraventricular nucleus [PVN] (function)
links nervous system to endocrine and autonomic systems
androstadienone [AND] (function)
potential human pheromone released by males; increases heart rate, slightly musky/sweaty smell reported by some people
who does AND affect?
homosexual men and heterosexual women in super high (abnormal) concentrations
what type of role does hormones play in humans?
a permissive role
what happens to boys who produced little testosterone at puberty and men who had both testes removed?
they show little interest in sex unless given testosterone (very little T is needed)
what MAY happen to women post menopause?
they SOMETIMES exhibit decreased sex drive and pain during sex (low levels of estrogen and testosterone can restore drive and experience)
parasympathetic pathway (function)
prootes blood flow and tissue relaxation in reproductive organs
what does the parasympathetic pathway connect?
the sacral segment of the spinal cord to the pelvic nerves
sympathetic pathway (function)
inhibits erections in males, facilitates early arousal and central excitation in females (secretes lubrication in both sexes)
what dies the sympathetic pathway connect?
the lumbar segment of the spinal cord to reproductive organs
what small mammal experienced pair bonds after sex, raise young, and groom together?
voles
what was special about the different vole species?
only ONE species pair bonds (higher levels of oxytocin)
oxytocin (function)
promotes positive feelings (high levels during orgasm), released during childbirth (positive feedback loop)
vasopressin [ADH] (function)
a peptide hormone and neurotransmitter that drives long-term commitment, monogamy, and loyalty (pair-bonding)
are vasopressin receptors within the vetral pallidum of a monogamus species of vole higher or lower than non-monogamus?
higher
ventral pallidum (function)
a core structure in the basal ganglia; major bridge between emotion, motivation, and physical movement
what is cognitive neuroscience?
exploration of cognitive brain pathways (language, attention, decision-making, learning/memory, conciousness)
what is neuroimaging technology used for?
a non-invasive way to look at a living brain's functions
what are some examples of neuroimaging technology?
EEG (electroencephalography), IEG ( immediate early genes), PET (positron emission tomography), FMRI (functional magnetic resonance imaging)
FMRI (steps)
1) subject is placed in strong magnetic field
2) magnetic molecules orient towards magnetic field (while completing genetic functions)
3) radio waves are sent
4) radio waves bump orientation
5) sends signals back at an angle to track WHERE and WHEN it occured
what can the FMRI detect?
oxygenated/deoxygenated blood (BOLD -> blood oxygen-level dependent signals)
why does the FMRI detect that?
active brain regions exhibit rapid decrease of oxy. blood (using it) then rapid increase (possibly because of astrocytes)
PET (steps)
1) subject is injected with radioactive glucose
2) glucose emits positrons (opposites of electrons)
3) positron meets electron and particles are annihilated
4) produces gamma ray emission
5) gamma ray detected around the subject
6) location of gamma ray in time and space can be calculated
what is the main question for studying deja vu?
how to study it without exposing subjects to large amounts of radiation
what neurological disorder did they study to test deja vu?
epilepsy
eliptogenic region (meaning)
where the seizure occurs
what did studies on deja vu find?
momentary changes on the hippocampus occurs which slightly alters recollection
what are words to babies?
sounds associated with environmental changes
why is the specific language window important?
it has high language plasticity
when could new language be learned in adulthood?
IF language was developed during the sensitive period
what do we learn from learning disorders that come from brain trauma?
it helps us understand the language parts of the brain
broca's aphasia (definition)
AKA non-fluent speech; there's difficulty producing speech but automatic speech isnt damaged
what part of the brain is impaired? (broca's aphasia)
the left inferior frontal lobe and middle cerebral artery
what deficit is thought to occur? (broca's aphasia)
a deficit in generating motor plans for vocalizations
wernicke's aphasia (definition)
AKA fluent aphasia; speech is nonsensical but fluid so comprehension is poor, has sound substitutions and word substitutions
what part of the brain is impaired? (wernicke's aphasia)
the left superior temporal gyrus
what deficit is thought to occur? (wernicke's aphasia)
a deficit in understanding the meaning of words
what else do aphasias apply to?
any fluent early learned language spoken, written language, sign language
endogenous/voluntary attention
conscious control of attention towards our interest or goal
overt attention
subsection of endogenous, sensory orientation
covert attention
subsection of endogenous, independent of sensory orientation
What cross-perception do overt and covert attention have?
auditory
exogenous/reflexive attention
involuntary re-orientation of attention to an unexpected stimulus
what happens when an attentional task is being performed?
activity in primary sensory cortices reflect attentional effort and reflect activity in subcortical region
what occurs when you're paying attention to what you SEE?
visual thalamus activates, prohibiting auditory thalamus
pulvinar (function)
region in the thalamus, critical in the ability to shift between auditory and visual
reticular activating system (function)
keeps neurons ready to go
what is consciousness?
the state of being awake and aware that we can perceive stimuli around us
The maternal immune hypothesis of environmental effects on male sexual orientation is related to...
a mother's immune response to a male fetus
Removal of the testes from a male rat right after birth organizes...
female-typical sexual behavior in adulthood
Evidence suggests that there are genetic influences on sexual orientation. (T/F)
true
Identical twins can have different sexual orientations. (T/F)
true
Adult homosexuals always behave in a gender-atypical fashion. (T/F)
false
Evidence suggests that, on average, male homosexuals have more ______ than male heterosexuals.
older brothers
An injection of testosterone to a female rat right after birth organizes...
male-typical sexual behavior in adulthood
The ______ of homosexual and heterosexual men differ.
hypothalamus
The "birth order effect" also known as the "older brother effect" on male sexual orientation appears to only be true for right-handed individuals. (T/F)
true
Evidence suggests that gender-atypical behavior in childhood is associated with adulthood homosexuality. (T/F)
true
A behavioral neuroscientist might study ______.
Aggression
It's easy to study sexual reflexes in rats because their sexual behavior is...
Stereotyped
The ______ found in rats, is larger in male brains than it is in female brains.
Sexually dimorphic nucleus of the hypothalamus
The phase of sexual behavior which some women experience multiple times during copulation is referred to as...
Orgasm
In men, very high levels of testosterone are needed to maintain interest in sexual behavior. (T/F)
false
Part of the ______ is larger in heterosexual men than it is in homosexual men.
Hypothalamus
In early fetal development in most mammals (including humans) there is an undifferentiated gonad that could become testes or ovaries. (T/F)
true
The ______ increases blood flow to genital tissue in both sexes.
Parasympathetic nervous system
A cognitive neuroscientist might study ______.
Attention
An fMRI scan can measure brain activity by detecting the BOLD signal. (T/F)
true
The neurohormone ______ is released during sexual behavior in voles (and other mammals) and is one important neural signal to form pair bonds.
Oxytocin
The decrease in estrogen levels in women after menopause is correlated with reduced sex drive. (T/F)
true
An fMRI scan requires that the subject be...
Placed in a strong magnetic field created by an electromagnet
In most male mammals (including humans), testes will form if ______ is present; in females, which lack this signaling molecule, ovaries will develop.
Testis-Determining Factor
Destruction of the ______ would eliminate sexual behavior in a male rat.
Sexually dimorphic nucleus of the hypothalamus