Hospital Drug Quiz 5 Counseling Points/Pearls

propofol side effects

propofol-related infusion syndrome (PRIS)

propofol monitoring

Triglycerides (serum TG concentration over 400 mg/dL)

propofol notes

Oil-in-water emulsion (opaque white solution); Provides 1.1 kcal/mL

ketamine, etomidate indications

Induction for anesthesia and/or intubation

dexmedetomidine indications

Sedation in intubated and non-intubated patients

dexmedetomidine notes

Duration of infusion should not exceed 24 hours

lidocaine indications

Used for local procedures, such as IV catheter insertion

lidocaine notes

Epinephrine is added for vasoconstriction, which keeps lidocaine localized

bupivacaine notes

Can be fatal if administered IV

ketorolac notes

Short-term use only

acetaminophen max dose

4g/day

acetaminophen black box

Risk of hepatotoxicity

fentanyl black box warning

Risk for abuse, misuse, and addiction; Use with strong or moderate 3A4 inhibitors increase effects and risk for respiratory depression

fentanyl notes

Potent, rapid-onset opioid commonly used for procedural sedation, anesthesia, and acute pain. Use conservative initial doses in opioid doses in opioid-naive patients and closely monitor respiratory status.

hydromorphone black box

Risk of medication error with high potency

morphine sulfate black box

Respiratory depression, risk for abuse, misuse, and addiction

morphine sulfate side effects

pruritis, constipation

nalbuphine indications

Used for obstetrical analgesia during labor and delivery

acetylcysteine indications

Acetaminophen overdose (IV); mucolytic to break up secretions

fomepizole indications

Ethylene glycol or methanol toxicity; Off-label for acetaminophen overdose