telomeres

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4 Terms

1
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what are telomeres

protective structures made of DNA sequences and proteins found at the ends of linear chromosomes

2
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what is the inherent problem in replicating the telomeres

Removal of the terminal RNA primer on the lagging strand leaves an unreplicated gap, causing telomeres to shorten with each replication cycle.

3
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how do cells prevent the loss from shortening telomeres

  1. the ends of chromosomes have simple, repeating sequences which do not contain protein-coding information.

  2. an enzyme called telomerase adds these repeated sequences back to the chromosome ends


4
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besides prevent erosion of genetic material what do telomeres do

telomeres preserve chromosomal integrity by associating with proteins to form a protective structure called a telomeric loop (t-loop)