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what is tumor lysis syndrome
cancer cells burst open and dump their contents into the blood
what increases with tumor lysis syndrome
hyperkalemia
hyperuricemia
hyperphophatemia
spinal cord compression
severe back pain + new neuro/ bladder symptoms → paralysis risk
SVC syndrome
facial swelling + dyspnea + distended veins
hypercalcemia
bone pain + kidney stones + confusion
third spacing
fluid is there but in the wrong place:
fluid leaks OUT of blood vessels → goes INTO tissues and spaces where it cant be used (ex: tissues and abdomen) → body looks wet on the outside but vessels are dry inside
what are the vessel signs in third spacing (vessel is dry)
hypotension
tachycardia
low urine output
** CRITICAL: NOT ENOUGH FLUID FOR PERFUSION
what are the body signs in third spacing (body looks wet)
edema
ascites
weight gain
** DANGER: FLUID IS STUCK AND CAUSING PROBLEMS
why is third spacing dangerous
fluid exists but cannot circulate → organs dont get perfused → SHOCK
a good memory trick for third spacing
swollen but dry
money in a broken ATM → the money is in the ATM but you cant use it
what shoud you watch with chemo patients
if their ANC drops below 500 = infection risk / SEVERE NEUTROPENIA
what is a normal ANC
1500 - 8000
neutropenic precautions
strict hand hygiene
no fresh flowers/ plants
no raw foods (cooked only)
avoid crowds and sick visitors
signs of a medical emergency in a chemo patient
fever (100.4 degrees fahrenheit) + chemo = medical emergency (SEPSIS)
what is thrombocytopenia
low platelets → cant clot = bleeding risk
normal platelet count
150,000 - 400,000
signs of thrombocytopenia
bruising
petechiae
bleeding gums
actions for thrombocytopenia patient
soft toothbrush
electric razor only
avoid IM injections
skin/ radiation care for a thrombocytopenic patient
protect skin from sun (sunburn= sun damage)
no lotions on radiation site unless prescribed
managing mucositis
avoid anything acidic or spicy
ice chips + frequent sips
soft/ bland foods
no alcohol- based mouthwash
managing peripheral neuropathy
always wear shoes even indoors
inspect feet daily
check bath water temp (CRUCIAL: can’t feel heat)
study shoes
numbness = FALL RISK
palliative care
relieves symptoms (pain/ nausea)
can still receive curative treatment (chemo/ radiation)
fluid volume deficit (FVD)
the dry patient
not enough fluid in the body → think dehydration on steroids
the body is desperately trying to compensate
what is the treatment and nursing care for FVD
isotonic fluids (NS or Lactated Ringers)
daily weights
strict I&O
what are the cardiovascular signs of FVD
tachycardia
hypotension
weak thready pulse
what are the skin signs of FVD
poor skin turgor (tenting)
dry mucous membranes
what labs are elevated in FVD
BUN/ creatinine
high urine specific gravity
what is a good memory trick for FVD
dry = everything HIGH
→ High HR, high labs, and high specific gravity
a high specific gravity would show as
concentrated urine (dehydrated/ FVD)
a low specific gravity would show as
diluted urine (overhydrated or DI)
fluid volume excess
the wet patient
too much fluid in the body
every system is overloaded and stressed
THE GOAL: get the fluid OFF
what are the cardiovascular signs of FVE
bounding pulse
JVD (jugular vein distention)
hypertension
what are the respiratory signs of FVE
crackles in lungs
dyspnea
what are general signs of FVE
edema
rapid weight gain
what is the treatment and nursing care for FVE
diuretics (furosemide)
fluid restriction
low sodium diet
high fowlers diet
isotonic solution
0.9% NS or Lactated Ringers
** SAME CONCENTRATION AS BLOOD
it says IN the vessel, does not shift anywhere
what is isotonic IV solution used for
FVD/ dehydration
trauma/ blood loss
surgery patients
hypovolemic shock
hypotonic solution
0.45% NS
water moves INTO cells to balance out
the cells swell up like a hippo (HYPO = HIPPO)
what is a hypotonic solution used for
cellular dehydration
hypernatremia (too much sodium so we ned to dilute it)
examples of a patient with cellular dehydration
hypernatremia patient
diabetic with very high blood sugar = glucose pulls water out of cells
patient who dank too much saltwater
hypertonic solution
3% NS
water moves OUT of cells into vessels
cells shrink like a raisin (HYPER=WIPER)
what would a hypertonic IV solution be used for
severe hyponatremia (dangerously low sodium)
severe cerebral edema
** MUST BE ADMINISTERED SLOWLY AND MONITORED CLOSELY
signs of hyponatremia
headache
confusion
seizures
coma
poor skin turgor
dry mucosa
treatment for hyponatremia
fluid restriction
signs of hypernatremia
thirst
dry sticky mucous membranes
restlessness
neuromuscular irritability
what is the treatment for hypernatremia
hypotonic fluids
signs of hypokalemia
muscle weakness
cramps
inverted T- waves
treatment for hypokalemia
IV potassium
** NEVER PUSH
nursing care for hypokalemic patients
always monitor ECG during IV administration
causes of hyperkalemia
renal failure
tumor lysis syndrome
signs of hyperkalemia
dysrhythmias
peaked T waves
treatment for hyperkalemia
kayexalate
insulin/ dextrose (insulin drives potassium FROM the blood INTO the cells → insulin activates the sodium potassium pump and that pump pushes potassium into cells BUT insulin drops blood sugar too so you cant give insulin alone → so you MUST give dextrose alongside with it)
signs of hypocalcemia
trousseau’s sign or chvostek’s sign
tetany, numbness (circumoral), laryngospasm
signs of magnesium toxicity
hypotensions
bradycardia
absent deep tendon reflexes
antidote for magnesium toxcitiy
calcium gluconate
primary prevention
prevent it
sunscreen
no smoking
vaccines
secondary
screening
mammogram
colonoscopy
pap smear
tertiary prevention
treatment/ rehab
nursing action for SVC syndrome
elevate head of bed
causes of metabolic acidosis
DKA
starvation
sepsis
renal failure
severe diarrhea
treatmenr for metabolic acidosis
treat the underlying cause
IV fluids
insulin (for DKA)
bicarbonate (if severe) → a base that directly neutralizes the acid
causes of metabolic alkalosis
severe vomiting
excessive gastric/ NG suction
long term diuretic use
metabolic alkalosis interventions
restore fluid volume with sodium chloride (NaCl)
replace potassium
administer antiemetics/ reduce suction
what are you monitoring the patient for with metabolic alkalosis
confusion
lethargy
cardiac dysrhythmias
→ because of the hypokalemia
causes of respiratory acidosis
hypoventilation
COPD/ asthma attacks
sedatives/ opioids
airway obstruction (tumors, anaphylaxis)
treatment for respiratory acidosis
improve ventilation
position in high fowler’s
bronchodilators
prepare for mechanical ventilation if respiratory rate drops dangerously low (ex: 7/min)
causes of respiratory alkalosis
hyperventilation
severe anxiety/ panic attacks
high altitudes
treatment for respiratory alkalosis
treat the underlying cause
antianxiety agents
have the patient breathe into a paper bag
what should you be watching for in a respiratory alkalosis patient
numbness, tingling of extremities, and muscle spasms
→ because alkalosis inhibits calcium ionization
clues of GERD
heartburn
regurgitation
chest burning after meals
what is the treatment for GERD
proton pump inhibitors
H2 blockers
lifestyle changes
what patient education are you providing to a GERD patient
keep the head of bed elevated
strictly avoid caffeine, alcohol, and late meals
clues of diverticular disease
left lower quadrant pain
fever
constipation
treatment for diverticular disease
antibiotics for infection
DURING A FLARE: low fiber diet, avoid seeds/ nuts
MAINTENANCE: high fiber diet
sudden, severe abdominal pain or a rigid, board- like abdomen is a sign of what
perforation
clues of ulcerative colitis
bloody diarrhea
severe abdominal pain
weight loss
priority interventions for an ulcerative colitis patient
keep patient NPO during exacerbations
IV hydration & anti- inflammatory medications
ONGOING DIET: high- calorie, low- fiber
ulcerative colitis patients are at a high risk for what
toxic megacolon
→ closely monitor I&Os, hypokalemia, and CBC levels
what is toxic megacolon
the colon becomes massively dilated and inflamed to the point it can rupture
difference between Crohn’s and UC (the location and presentation)
LOCATION: crohns is anywhere in the GI tract (from mouth to anus) while UC is in the colon only
PRESENTATION: crohns is patchy inflammation (skipped lesions) while UC is a continuous inflammation starting from the rectum
a patient presents with RUQ pain after fatty meals and clay colored stool. what disorder is most likely
cholelithiasis