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For patient doesn’t have time for a full night of sleep + has trouble falling asleep
Zaleplon
Short-acting agent that has more restricted use
Triazolam
Causes complex sleep behaviors + has next-day impairment if patient doesn’t sleep enough
Zolpidem IR
Agent that causes taste disturbances and complex sleep behaviors
Eszopiclone
Best and most “first-line” out of the intermediate-acting agents
Eszopiclone
Has more next-day impairment than eszopiclone
Zolpidem ER
Narcolepsy CI
Daridorexant
Causes sleep paralysis/cataplexy-like effects
Suvorexant
Avoid in older adults/BPH/glaucoma
Diphenhydramine
Avoid chronic use
Doxylamine
Best option for maintenance
Doxepin 3-6mg
“Last resort” for long-acting agents
Lemborexant