BIO 101 Ch.11: DNA

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10 Terms

1
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Friedrich Miescher

  • 1869

  • Discovered a phosphate-rich material he called “nuclein” in the nuclei of white blood cells


2
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Albret Kossel

  • 1878

  • Isolated nucleic acids apart from proteins associated with it

  • Discovered that nucleic acids were made from 5 diff subunits


3
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Phoebus Levene

  • 1919

  • Discovered that each subunit of a nucleic acid was made of a sugar, base, and a phosphate


4
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Frederick Griffith

  • 1928

  • “Transforming principle”


5
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Oswald Avery

  • 1943

  • Found out that nucleic acids were the “transforming factors,” and that DNA was the molecule of genetic inheritance


6
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Erwin Chargaff

  • 1950

  • Amount of adenine = thymine; guanine = cytosine


7
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Martha Chase and Alfred Hershey

  • 1952

  • DNA, not proteins, are the molecules for genetic inheritance


8
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Rosalind Franklin

  • Crystallized DNA to make an X-ray diffraction pattern of it

  • Discovered DNA double-helix structure


9
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Maurice Wilkins

  • 1952

  • Rivalry with Franklin

  • Won the Nobel Peace Prize along with Watson and Crick


10
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James Watson and Francis Crick

  • 1953

  • Proposed 3D structure of DNA