Clin Chem MediaLab

The bioavailability of an oral drug refers to the:

Availability for therapeutic administration

Ratio of protein-bound to free drug

Amount of drug transformation

Fraction of the drug that is absorbed into the systemic circulation

Fraction of the drug that is absorbed into the systemic circulation

L3

What is the formula for calculating transferrin saturation (TS)?

(Serum iron/TIBC) X 100

(Serum ferritin/TIBC) X 100

TIBC/serum iron

Serum iron/serum ferritin

(Serum iron/TIBC) X 100

L5

What is the threshold limit value?

The maximum level of a chemical to which a worker can be exposed without causing adverse health effects.

The temperature at which a chemical will ignite.

The amount of water needed to dilute a chemical for laboratory use.

The amount of a chemical that can legally be stored in a laboratory.

The maximum level of a chemical to which a worker can be exposed without causing adverse health effects.

All of the following are characteristics of type 2 diabetes mellitus EXCEPT:

Insulin levels may or may NOT be abnormal.

More common than type 1 diabetes.

Requires insulin therapy to control hyperglycemia.

It commonly occurs in adults.

Requires insulin therapy to control hyperglycemia.

The risk of exposure of a person to an infection of tuberculosis (TB) disease may be related to which of the following:

Born in the United States

High social status

Socially disadvantaged

Person in non-high-risk groups

Socially disadvantaged

To assess drug concentrations during the trough phase, blood should be drawn:

Please select the single best answer

About one 15 minutes after the administration of an oral dose of the drug.

Immediately before the next dose is given.

About three hours after the administration of an oral dose of the drug.

About an hour before the administration of an oral dose of the drug.

Immediately before the next dose is given.

Which of the following must be included as part of a PCR in order to quantify unknown samples?

Please select the single best answer

Positive control

Negative Control

Internal Control

Standards

Standards

Which of the following contributes most to serum osmolality:

Please select the single best answer

Magnesium

Albumin

Potassium

Sodium

Sodium

Which of the following analytes would be increased due to delay in centrifugation?

Please select the single best answer

Creatinine

Ionized Calcium

Folate

Bicarbonate

Creatinine

Which of the following statements is true regarding cardiovascular disease and adipose tissue?

Please select the single best answer

Inflammatory cytokines, synthesized and released by adipose tissue, contribute to the development of cardiovascular disease.

Increased synthesis and secretion of PAI-1 in metabolic syndrome contributes to cardiovascular disease by increasing blood pressure.

Obesity in metabolic syndrome contributes to the development of cardiovascular disease by increased synthesis and secretion of adiponectin.

There is no correlation between the amount of adipose tissue and cardiovascular disease.

Inflammatory cytokines, synthesized and released by adipose tissue, contribute to the development of cardiovascular disease.

You are collecting a blood specimen to be used for forensic (legal) alcohol testing. Which of the following must be done before you can start the specimen collection process?

Please select the single best answer

Label the tubes in the presence of the patient.

Must inform the patient that the blood about to be collected is for alcohol testing.

Seal the collection tubes in front of the patient.

Collect the specimen, the patient does not need to be informed what the blood is collected for.

Must inform the patient that the blood about to be collected is for alcohol testing.

Precision is a measure of:

Please select the single best answer

Method accuracy

Random variability

Method reliability

Biological variability

Method reliability

You are working to validate a new method for detecting C-reactive protein (CRP) in serum. To assess precision, you run a medium-level control 30 times and determine the mean to be 4.0 mg/dL with a standard deviation of 0.04 mg/dL. What could be said about the precision of this run, assuming a CV less than 3% is acceptable?

Please select the single best answer

It is not acceptable, with a coefficient of variation of 100%.

It is not acceptable, with a coefficient of variation of 10%.

It is acceptable, with a coefficient of variation of 0.1%.

It is acceptable, with a coefficient of variation of 1%.

It is acceptable, with a coefficient of variation of 1%.

Which of the following enzymes is the most sensitive indicator of long term liver damage associated with alcohol ingestion:

Please select the single best answer

Gamma-glutamyl transpeptidase (GGT)

Alanine transaminase (ALT)

Aspartate transaminase (AST)

Lactate dehydrogenase (LDH)

Gamma-glutamyl transpeptidase (GGT)

When is a trough blood sample for therapeutic drug monitoring usually obtained?

Please select the single best answer

Just after the dose is administered

Just before the next scheduled dose

At the peak time calculated after a dose

After one half-life of the drug

Just before the next scheduled dose

What is the approximate time that should be allowed for samples to completely clot before centrifugation for serum samples?

Please select the single best answer

5 minutes

10 minutes

15 minutes

20 minutes

20 minutes

A 46-year-old woman was admitted to the hospital through the emergency room after having a bout of severe diarrhea for 3 days along with headaches, muscle aches, shortness of breath, and an increased heart rate. Blood gas measurements were ordered by her concerned physician. The results showed the following:

pH = 7.30

pCO2 = 32 mm Hg

HCO3- = 15 mmol/L

pO2 = 93 mmol/L

What acid-base disorder is most consistent with this patient's results and symptoms?

Please select the single best answer

Respiratory acidosis

Respiratory alkalosis

Metabolic acidosis

Metabolic alkalosis

Metabolic acidosis

A patient with renal failure is seen for blood work. What would you expect the serum calcium and phosphorus levels to be in this patient?

Please select the single best answer

Increased calcium and phosphorus levels

Decreased calcium and phosphorus levels

Increased calcium but decreased phosphorus levels

Decreased calcium but increased phosphorus levels

Decreased calcium but increased phosphorus levels

Which of the following methods may be used by a laboratory to document and analyze all of the steps that bring a laboratory test result to the customer (eg, physician, nurse, and/or patient)?

Please select the single best answer

Root cause analysis

Value stream mapping

5S

Kaizen workshop

Value stream mapping

Which of the following conditions should be suspected if a healthy patient presents with an elevated potassium level while all other chemistry results are normal?

Please select the single best answer

The sample is turbid.

The sample is hemolyzed.

The sample is clotted.

The sample is lipemic.

The sample is hemolyzed.

Hydrogen ion concentration (pH) in blood is usually determined by means of which of the following electrodes?

Please select the single best answer

Silver

Glass

Platinum

Gold

Glass

The risk of laboratory-acquired infections with viruses, such as HIV-1, is a critical consideration. All of the following routes are considered modes of transmission with infected blood or other body fluids, EXCEPT?

Please select the single best answer

Contact of the hand (non-intact skin)

Contact with eyes

Contact with mouth

Inhalation (airborne transmission)

Inhalation (airborne transmission)

The greatest source of error in point of care testing is:

Please select the single best answer

Selection of POCT analyzer or methodology

Preanalytical error

Analytical Error

Postanalytical Error

Preanalytical error

MOST of the carbon dioxide present in the blood is in the form of:

Please select the single best answer

Bicarbonate

Carbonate

Carbonic acid

Dissolved CO2

Bicarbonate

What measures the concentration of solute particles in a solution?

Please select the single best answer

Osmometer

Fluorometer

Nephelometer

Spectrophotometer

Nephlometer

When operating a centrifuge, what happens if the centrifugation time is reduced and the speed increased?

Please select the single best answer

The potential breakage of collection tube is highly increased.

There is increased chance of exposure to biohazardous agents.

There will be incomplete separation of red blood cells and serum in the tube.

Mechanical damage to the centrifuge may occur.

There will be incomplete separation of red blood cells and serum in the tube.

All of the following statements about blood cultures are correct, EXCEPT:

Please select the single best answer

The volume of blood collected is important. Short draws will reduce the likelihood of successfully growing out bacteria.

If two separate sets of blood cultures are requested, do not draw them both from the same site at the same time.

Be sure to allow the iodine prep to dry on the patient's skin prior to performing the blood culture.

Since all gloves are sterile, you may use your gloved finger without further preparation to feel the vein on a prepped arm before making the stick.

Since all gloves are sterile, you may use your gloved finger without further preparation to feel the vein on a prepped arm before making the stick.

When measuring enzyme activity, if the instrument is operating 5ºC lower than the temperature prescribed for the method, how will the results be affected?

Please select the single best answer

Lower than actual

Higher than actual

Varied, showing no particular pattern

No effect

Lower than actual

What section of the SDS would provide information about whether a chemical is carcinogenic?

Please select the single best answer

Physical and chemical data

Health hazard data

Reactivity data

Handling and storage data

Health hazard data

Which of the following BEST describes the relation of nephelometry to turbidimetry?

Please select the single best answer

Nephelometry measures the amount of light absorbed by particles in solution, and turbidimetry measures the amount of light transmitted through a solution

Nephelometry directly measures the amount of light scattered by particles in solution, and turbidimetry measures the decrease in incident-light intensity

Nephelometry measures the amount of light emitted by particles in solution, and turbidimetry measures the amount of light reflected by particles in solution

Nephelometry measures the amount of light absorbed, and Turbidimetry measures the amount of light scattered

Nephelometry directly measures the amount of light scattered by particles in solution, and turbidimetry measures the decrease in incident-light intensity

Regarding therapeutic drug monitoring, which of the following statements is correct when collecting a specimen for a trough level?

Please select the single best answer

Trough level is tested on a blood sample that is collected after a dose of the drug is given (at a specified time).

Trough level is the point at which the drug is highest in the patient's body.

Trough level is tested on a blood sample that is collected immediately prior to when the next dose of the drug is given.

Trough level is collected randomly, there is no specific time for it.

Trough level is tested on a blood sample that is collected immediately prior to when the next dose of the drug is given.

Which of the following best defines "specificity":

Please select the single best answer

A test's ability to correctly identify individuals who have a given disease or disorder.

A test's ability to correctly exclude individuals who do not have the given disease or disorder.

Ability of a test to detect small amounts of a substance or to measure a reaction.

The measurement or detection of a select substance provides important information about an illness or about health status that assists in the diagnosis, treatment, or monitoring of a patient.

A test's ability to correctly exclude individuals who do not have the given disease or disorder.

At a medical examination, a 50-year-old Caucasian male expressed concern regarding diabetes. There is a history of type 2 diabetes, hypertension, and cardiovascular disease in his family. He has gained a few pounds each year, and his physician notes abdominal obesity. His physician orders laboratory tests to evaluate his risk of cardiovascular disease.

Vital Signs and Pertinent Laboratory Results:

Blood Pressure: 128/82 mm Hg

Weight: 230 lbs

Height: 5' 11''

Calculated BMI: 32.1

Waist Circumference: 45 inches

Fasting Blood Glucose: 120 mg/dL

Triglycerides: 170 mg/dL

HDL-C: 42 mg/dL

Which one of the following statements regarding this patient is true if the physician uses the American Heart Association (AHA) and National Heart, Lung, Blood Institute (NHLBI) guidelines for metabolic syndrome evaluation?

Diagnosis of metabolic syndrome; waist circumference, HDL-C, and fasting blood glucose meet the criteria

Diagnosis of metabolic syndrome; waist circumference, triglyceride level, and fasting blood glucose meet the criteria

It does not meet the criteria for diagnosis of the metabolic syndrome because the HDL-C is not

Diagnosis of metabolic syndrome; waist circumference, triglyceride level, and fasting blood glucose meet the criteria

What accelerates the rate of lipase activity in the body?

Please select the single best answer

Presence of water

Presence of bile salt

Absence of bile salt

Presence of alcohol

Presence of bile salt

The Emergency Department has collected blood test tubes for potassium, albumin, plasma hemoglobin, and acid phosphatase. Which of these test results will NOT be negatively affected if the blood tube is sent by the hospital's pneumatic tube system?

Please select the single best answer

Albumin

Plasma hemoglobin

Potassium

Acid phosphatase

Albumin

Toxic levels of lithium can cause lethargy, apathy, muscle weakness up to and including seizures and coma. What is the toxic level of lithium?

Please select the single best answer

0.5-1.2 mmol/L

1.2-1.5 mmol/L

1.5-2 mmol/L

>2 mmol/L

1.5-2 mmol/L

Which of the following is the prodrug of phenobarbital?

Please select the single best answer

Fosphenytoin

Ethosuximide

Primidone

Gabapentin

Primidone

Convert 0.9% NaCl to molarity.

Please select the single best answer

0.15M

0.25M

0.39M

1.50M

0.15M

Which of the following clinical laboratory departments performs the most tests?

Please select the single best answer

Urinalysis

Microbiology

Clinical Chemistry

Hematology

Clinical Chemistry

Which of the following blood tests is used in the evaluation of hepatic disease?

Please select the single best answer

Amylase

Alanine aminotransferase (ALT or SGPT)

Creatinine

Alkaline phosphatase (ALP)

Alanine aminotransferase (ALT or SGPT)

What is the normality of 32.1% HCl? (HCl has a positive valence of 1)

Please select the single best answer

3.2N

8.8N

11.2N

15.7N

8.8N

Which of the following is most likely to interfere with the measurement of hemoglobin?

Please select the single best answer

Leukocytopenia

EDTA

Heparin

Lipemia

Lipemia

All of the following are types of quality and process improvement tools, EXCEPT:

Please select the single best answer

Six Sigma

Lean

Sentinel events

Root-cause analysis

Sentinel events

When flammable chemicals or grease are involved, what is the appropriate fire designation?

Please select the single best answer

Class A

Class B

Class C

Class D

Class B

The term, analytical specificity, refers to:

Please select the single best answer

The ability to measure only that substance being assayed.

The ability to measure the range of concentration in a sample without modification.

The ability to detect low concentrations of analytes.

The ability of the measuring system to change in response to a change in concentration of analyte.

The ability to measure only that substance being assayed.

Which organisms are the appropriate stock cultures for quality control testing of oxidase production?

Please select the single best answer

Escherichia coli / Klebsiella pneumoniae

Salmonella typhimurium / Escherichia coli

Escherichia coli / Pseudomonas aeruginosa

Proteus mirabilis / Escherichia coli

Escherichia coli / Pseudomonas aeruginosa

The impedance principle shown in this illustration is best described by the following statement:

Please select the single best answer

Blood cells and platelets are counted by the number of the times they scatter light as they pass in front of a mirror.

Blood cells and platelets are counted utilizing a type of diffraction gradient technique.

Blood cells and platelets are counted by measuring the drop in transmitted light as they pass through a series of apertures.

Blood cells or other particles are counted and sized based on changes in electrical resistance as they pass between two electrodes.

Blood cells or other particles are counted and sized based on changes in electrical resistance as they pass between two electrodes.

In healthy individuals, calcitonin is synthesized by which cells in the body?

Please select the single best answer

Hepatocytes

Leukocytes

Thyroid C cells

Red blood cells

Thyroid C cells

Which porphyria has a defect in the ferrochetalase enzyme within the RBC, causing redness, edema and burning when exposed to light?

Please select the single best answer

Erythropoietic protoporphyria

Congenital erythropoietic porphyria

X-linked protoporphyria

Variegate porphyria

Erythropoietic protoporphyria

Which type of electrophoresis is used to separate larger DNA fragments (>50 kb)?

Please select the single best answer

Polyacrylamide gel electrophoresis

Capillary electrophoresis

Isoelectric focusing

Pulsed field electrophoresis

Pulsed field electrophoresis

Which of the following instruments measures the amount of electricity passing between two electrodes?

Please select the single best answer

Osmometer

Coulometer

Nephelometer

Spectrophotometer

Coulometer

Six months ago, a 55-year-old female had a fasting plasma glucose (FPG) greater than 200 mg/dL on two occasions. She was diagnosed as having type 2 diabetes and treatment was started. Along with routine FPG's which of the following tests would most likely be used to monitor glycemic control?

Please select the single best answer

HbA1C

Insulin

C-peptide

Urine glucose

HbA1C

Which of the following analytes would be increased due to delay in centrifugation?

Please select the single best answer

Bicarbonate

AST

Glucose

Ionized Calcium

AST

Which analyte measurement is used to detect early nephropathy in a diabetic patient?

Please select the single best answer

Lactic acid

Albumin

Ketones

HbA1C

Albumin

Which of the following instruments measures changes in vapor pressure?

Please select the single best answer

Osmometer

Coulometer

Nephelometer

Spectrophotometer

Osmometer

Which of the following is considered the major transport protein for vitamin A?

Please select the single best answer

Transthyretin

Retinol-binding protein

Transferrin

Haptoglobin

Retinol-binding protein

A medical event occurs that results in serious injury to a patient. All systems, processes, and common causes that were involved in the adverse event should be evaluated. A method that can be implemented to effectively study the underlying causes is known as:

Please select the single best answer

Failure mode and effect analysis

Monitoring of quality indicators

Medical record audit

Root cause analysis

Root cause analysis

Which of the following tests require a 72-hour stool (fecal) collection?

Please select the single best answer

Occult blood

Quantitative fecal fat

Ova and Parasite (O&P)

Stool culture

Quantitative fecal fat

Compliance standards, policies and procedures apply to:

Please select the single best answer

Only employees who work in risk areas of the laboratory.

All employees in the company regardless of their position, job description, or title.

Only the billing department.

Any employee involved in the compliance program or the legal department.

All employees in the company regardless of their position, job description, or title.

What is the normality (N) of a 700 mL solution that contains 5 g of H2SO4 (gmw=98 g/mol, valence=2)?

Please select the single best answer

0.146 N

0.00014 N

0.023 N

0.841 N

0.146 N

Which of the following terms is used to identify an individual who has enough Six Sigma training to participate on a performance improvement team or lead small-scale projects within his/her work unit, but does not work on Six Sigma projects full-time?

Please select the single best answer

Green belt

Black belt

Master black belt

Sponsor

Green belt

At what frequency must the temperature of a chart recorder be compared to a thermometer?

Please select the single best answer

Daily

Monthly

Quarterly

Annually

Daily

The analysis of DNA products using automated molecular testing equipment has the listed advantages EXCEPT:

Please select the single best answer

Automated equipment for molecular testing is less expensive to purchase and maintain.

Automated equipment for molecular testing produces products with greater specificity and sensitivity.

Automated equipment for molecular DNA amplification products produces more consistent product quality.

Automated equipment for molecular testing requires a smaller sample volume.

Automated equipment for molecular testing is less expensive to purchase and maintain.

A hepatic function panel A consists of which of the following tests?

Please select the single best answer

AST, ALT, Alkaline Phosphatase, Total Protein, Albumin, Total Bilirubin, Direct Bilirubin

Glucose, BUN, Creatinine, Sodium, Potassium, Chloride, CO2, Calcium

Cholesterol, Lipoprotein, HDL, Triglycerides

Potassium, Sodium, Chloride, CO2

AST, ALT, Alkaline Phosphatase, Total Protein, Albumin, Total Bilirubin, Direct Bilirubin

Which of the following microscopic techniques is best suited for direct examination of the infectious agent of syphilis?

Please select the single best answer

Light microscopy

Phase-contrast microscopy

Dark-field microscopy

Electron microscopy

Dark-field microscopy

How many milliliters of 3N solution can be made from 50g of CaCl2?

Please select the single best answer

150 mL

300 mL

3333 mL

6666 mL

300 mL

The preparation of a Levey-Jennings quality control chart for any constituent of serum requires:

Please select the single best answer

A minimum of 20-30 analyses of control serum over a period of 20-30 days.

20-30 analyses of control serum on one day, one batch.

Daily analyses for 1 month with the use of aliquots from more than one lot control serum.

20-30 analyses performed by one person.

A minimum of 20-30 analyses of control serum over a period of 20-30 days.

Which analyte should be increased in the presence of gout?

Please select the single best answer

Uric acid

Aldolase

Amylase

Troponin

Uric acid

Which of the following drugs is used to treat asthma and COPD in patients with nocturnal symptoms or problems with inhalers?

Please select the single best answer

Theophylline

Methotrexate

Tacrolimus

Mycophenolic acid

Theophylline

Which of the following procedures would you employ to monitor the precision of an assay?

Please select the single best answer

Run assayed controls

Run blinded samples

Run samples by an alternative method

Run samples in duplicate

Run samples in duplicate

Zollinger-Ellison syndrome is characterized by a large (usually 20-fold) elevation of:

Please select the single best answer

Cholecystokinin

Pepsin

Glucagon

Gastrin

Gastrin

What is the correct method employers must notify employees regarding the results of formaldehyde monitoring?

Please select the single best answer

Individually in writing or by posting the results in an appropriate location that is accessible to employees.

Employers are not required to report to employees.

During the annual performance review meeting.

Posting information on the Employer's Facebook page.

Individually in writing or by posting the results in an appropriate location that is accessible to employees.

All of the following factors affect hybridization, EXCEPT:

Please select the single best answer

G:C content

A:T content

pH

Temperature

A:T content

Which of these processes would be characteristic of "Lean" laboratory production?

Please select the single best answer

Hold routine specimens in the specimen processing area until all phlebotomists have completed their morning rounds.

Process and deliver patient samples to the testing areas in batches.

Load patient samples onto automated analyzers as the samples arrive to the work area.

Techs constantly leaving their workstation to locate regularly used supplies for their bench.

Load patient samples onto automated analyzers as the samples arrive to the work area.

Heparin interacts with _____________, which subsequently inhibits thrombin.

Please select the single best answer

Red blood cells

White blood cells

Antithrombin III

Protein C

Antithrombin III

An MCV is reported by the instrument as 82 fL. The MCV is flagged with a delta check alert as the previous MCV reported on this patient 12 hours earlier was 97 fL. What is a possible cause for this discrepancy?

Please select the single best answer

Transfusion

The specimens are not from the same patient

Acute hemorrhage

The second specimen was hemolyzed

The specimens are not from the same patient

How can a phlebotomist help to reduce pre-analytical variability associated with sample collection?

Please select the single best answer

Avoid keeping the tourniquet applied for a prolonged period of time.

Select a needle gauge that is appropriate for the size of the evacuated blood tube used.

Avoid collecting blood from an arm that is receiving an intravenous (IV) solution.

All of these techniques help to minimize the pre-analytical variability related to sample collection.

All of these techniques help to minimize the pre-analytical variability related to sample collection.

A serum specimen for potassium testing is collected in a red top tube without a gel separator barrier. If testing is delayed by a few hours, how should the specimen be handled?

The correct answer is highlighted below

Discard the specimen and recollect right before testing is available again.

Discard the specimen and recollect in a gel separator tube.

The specimen should be centrifuged as soon as it clotted and serum should be transferred to another tube.

There is no special handling procedure for this specimen.

The specimen should be centrifuged as soon as it clotted and serum should be transferred to another tube.

GGT (gamma-glutamyltransferase) is an enzyme found in many body tissues including the kidney, prostate, brain, pancreas, and liver, however, its clinical applications is confined to the evaluation of what system?

Please select the single best answer

Pancreas

Liver

Kidney

Brain

Liver

Does the Levey-Jennings chart to the right show acceptable quality control results?

Please select the single best answer

No, because of Westgard Rule 13s

No, because of Westgard Rule 22s

No, because of Westgard Rule 41s

Yes

Yes

How would you CORRECTLY prepare 100 mL of 0.9% isotonic saline (NaCl: GMW = 58.45)?

Please select the single best answer

0.9 grams in 100 mL distilled water

9.0 grams in 100 mL distilled water

0.526 grams in 100 mL distilled water

5.84 grams in 100 mL distilled water

0.9 grams in 100 mL distilled water

A reaction is in ____________ kinetics when the reaction rate depends only on enzyme concentration.

Please select the single best answer

Zero-order

First-order

Second-order

Mixed-order

Zero-order

EDTA and Sodium citrate combine with _________ to inhibit coagulation in blood samples.

Please select the single best answer

Potassium

Calcium

Magnesium

Sodium

Calcium

A physician discusses weight with an overweight 60-year-old female at her yearly physical appointment. The female exercises regularly and eats healthy most of the time. The physician suggests she decrease carbohydrate intake and decrease portion size at meals.

Review patient vital signs and laboratory assay results to decide if a diagnosis of metabolic syndrome is appropriate using the NCEP: ATP III Diagnostic Criteria shown on the right.

Height: 5' 7'

Weight: 192 lbs

BMI: 30.1

Waist Circumference: 37 inches

Blood Pressure: 108/70

Fasting Blood Glucose: 92 mg/dL

Total Cholesterol: 172 mg/dL

LDL-C: 112 mg/dL

HDL-C: 46 mg/dL

Triglycerides: 70 mg/dL

hs-CRP:

This patient does not meet the criteria for diagnosis of metabolic syndrome.

A chemical reaction that is utilized by many different analytical methods involves:

Please select the single best answer

Fluorometry

Glucose oxidase

The reduction of NAD to NADH

UV spectrophotometry

The reduction of NAD to NADH

A patient is seen in the ER for abdominal pain and jaundice (yellowing of the skin and sclera). A quick urinalysis is performed, and it is noted there is an increase in urine urobilinogen. All of the following are likely causes EXCEPT:

Please select the single best answer

Hepatitis

Hemolytic episode

Cholelithiasis

Chronic liver disease

Cholelithiasis

Calculate the specificity for the following medical research project completed by a manufacturer:

Test Results

Positive Negative

Disease 984 7

No Disease 16 873

Please select the single best answer

98.2%

98.4%

99.1%

99.99%

98.2%

true neg/(true neg + false pos)

According to the American Diabetes Association recommendations, which of the following statements is TRUE with regards to the following findings?

Fasting glucose = 130 mg/dL

2-hour post prandial glucose = 210 mg/dL

Please select the single best answer

The patient may be diagnosed as having diabetes mellitus

The patient is diagnosed as having impaired glucose tolerance

The patient is diagnosed as having diabetes insipidus

The patient is normal

The patient may be diagnosed as having diabetes mellitus

Pheochromocytoma is a tumor of the adrenal medulla that results in elevated urinary levels of all the following EXCEPT:

Please select the single best answer

Cortisol

Free catecholamines

Metanephrines

Vanillylmandelic acid

Cortisol

Increases in blood ammonia levels would be expected in which of the following conditions:

Please select the single best answer

Diabetes

Obstructive jaundice

End-stage cirrhosis

Myocardial infarction

End-stage cirrhosis

Which of the following tests would be most affected by microclots in an EDTA tube drawn for a CBC?

Please select the single best answer

RBC

Hematocrit

Hemoglobin

Platelet count

Platelet count

To properly use a volumetric pipette calibrated "to deliver" (TD), one should:

Please select the single best answer

Let the pipette drain in a vertical position and blow out the last drop.

Drain the contents in the vertical position but do not blow out.

Drain the pipette after rinsing out the contents several times and blow out the last drop.

Contain a specified amount of liquid but are not necessarily calibrated to deliver that exact amount.

Drain the contents in the vertical position but do not blow out.

All of the following are types of quality and process improvement tools, EXCEPT:

Please select the single best answer

Six Sigma

Lean

Sentinel events

Root-cause analysis

Sentinel events

Which of the following conditions would be suggested by a jaundiced patient experiencing a marked rise in alkaline phosphatase (ALP), conjugated bilirubin, and a slight rise in alanine aminotransferase (ALT)?

Please select the single best answer

Cardiovascular disease

Hepatitis

Post-hepatic cholestasis

Renal failure

Post-hepatic cholestasis

Which of the following electrolytes is most likely to be spuriously elevated in a hemolyzed specimen?

Please select the single best answer

Sodium

Potassium

Chloride

BUN

Potassium

Safety regulations in the clinical laboratory fall under which government agency?

Please select the single best answer

Centers for Disease Control

College of American Pathologists

Food and Drug Administration

Occupational Safety and Health Administration

Occupational Safety and Health Administration

The migration rate of proteins on cellulose acetate is primarily the result of:

Please select the single best answer

Molecular content of the protein

Ionic charge on the proteins

Concentration of the proteins

Type of proteins

Ionic charge on the proteins

Good Manufacturing Practices applies to all of the following, EXCEPT:

Please select the single best answer

Blood

Progenitor cells

Tissue

Waste

Waste

In which of the following condition(s) would an increased serum osmolality be an expected finding?

Please select the single best answer

Increased arginine vasopressin hormone (AVP formerly ADH) secretion

Diabetes insipidus

Hyponatremia

Acute myocardial infarction

Diabetes insipidus