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What is the all-or-nothing electrical brain response in brain cells?
a) synapse
b) action potential
c) neuron
d) neurotransmitters
b) action potential
Yui is interviewing a patient known as "H.M.", who began having memory issues after his hippocampus was removed. This is an example of an _____________ study:
a) experimental
b) case
c) pseudoscientific
d) observational/quisi-experimental
b) case
Jana is searching for the genetic cause of Alzheimer's disease. Her research suggests that Alzheimer’s patients are more likely to have the APOE4 gene than normal patients. This is an example of an _____________ study:
a) pseudoscientific
b) case
c) observational/quasi-experimental
d) experimental
c) observational/quasi-experimental
Rafael is changing the genetic expression of neurons in mice to see if they can learn how to navigate a maze faster. This is an example of an _____________ study:
a) observational/quasi-experimental
b) experimental
c) pseudoscientific
d) case
b) experimental
Mark all myths about neuroscience and the brain.
a) Forming memories causes new neurons to be born.
b) We only use 10% of our brain.
c) The brain cannot repair itself.
d) Your personality reflects whether you are left or right brain dominant.
All
Which of these regions is NOT part of the peripheral nervous system?
a) somatic nervous system
b) parasympathetic nervous system
c) enteric nervous system
d) spinal cord
d) spinal cord
Match each description (left) with the correct anatomical term (right).
a) A grooved indentation running along the anterior-posterior axis of the brain, dividing it in half.
b) The outer surface of the brain
c) Raised ridges on the brain.
Gyri
Longitudinal fissure
Cortex
a) A grooved indentation running along the anterior-posterior axis of the brain, dividing it in half. — Longitudinal fissure
b) The outer surface of the brain — cortex
c) Raised ridges on the brain — gyri
What is the term for the "empty" spaces in the brain that are filled with cerebrospinal fluid?
a) ventricles
b) BBB
c) meninges
d) Circle of Willist
a) ventricles
Which of these vesicles contains the cerebral cortex and is involved in memory and language?
a) telencephalon
b) metencephalon
c) diencephalon
d) mesencephalon
a) telencephalon
Which fragile layer of the meninges directly contacts the brain?
a) Circle of Willis
b) arachnoid mater
c) dura mater
d) pia mater
d) pia mater
Ramon y Cajal suggested that the nervous system was composed of one large, interconnected system
True or False?
False
Which statement about neurons is FALSE?
a) neurons can change
b) neurons are capable of sending signals to other cells
c) neurons are continually replaced
d) neurons have electrical charge
c) neurons are continually replaced
Which part of the neuron resembles a tree?
a) axon
b) dendrites
c) axon terminal
d) soma
b) dendrites
Which glia interacts with synapses?
a) oligodendrocytes
b) microglia
c) ependymal cell
d) astrocytes
e) Schwann cells
d) astrocytes
The resting potential is usually considered to be:
a) -70 mV
b) -55 mV
c) +55 mV
d) +70 mv
a) -70 mV
The action potential threshold is:
a) +70 mV
b) +55 mV
c) -70 mV
d) -55 mV
d) -55 mV
Why does Na+ want to enter the neuron at rest?
a) the chemical gradient
b) the electrochemical gradient
c) it does not want to enter the neuron
d) the electrical gradient
b) the electrochemical gradient
Why does K+ want to leave the neuron at rest?
a) the electrochemical gradient
b) the electrical gradient
c) the chemical gradient
d) it does not want to leave the cell
a) the chemical gradient
What type of ion channel is most responsible for the changes of voltage seen during an action potential:
a) ligand-gated
b) voltage-gated
c) leak
d) electrochemical-gradient-gated
b) voltage-gated
Match the phases of an action potential (right) with the corresponding changes in Na+ and K+ ion channels.
a) depolarization
b) repolarization
c) hyperpolarization
d) resting phase
Na+ channels are closed, K+ channels are deactivating
Na+ channels are inactivated, K+ channels are open
Na+ channels are open, K+ channels are open
Na+ channels is closed, K+ channels are closed
a) depolarization — Na+ channels are open, K+ channels are open
b) repolarization — Na+ channels are inactivated, K+ channels are open
c) hyperpolarization — Na+ channels are closed, K+ channels are deactivating
d) resting phase — Na+ channels is closed, K+ channels are closed
What is NOT true about vesicles?
a) Have V-snares embedded in them
b) Hold neurotransmitters
c) They are filled using ion channels
d) Increases in calcium leads them to fuse with the cell membrane
c) They are filled using ion channels
What is NOT required to form a SNARE complex?
a) t-SNARE
b) Ca2+
c) v-SNARE
d) G-proteins
d) G-proteins
What is NOT true about receptors?
a) Metabotropic receptors, also called G-protein receptors, rely upon secondary messengers rather than direct changes in ion concentration
b) They are shaped to fit a specific neurotransmitter.
c) They can be located on both pre- and post-synaptic cells.
d) Neurons can only have one type of receptor.
d) Neurons can only have one type of receptor.
The amount of neurotransmitters released must be closely regulated. For example, too much glutamate may lead to cell death.
True/False
True
Both serotonin and norepinephrine are made in the brain stem.
True/False
True
Which of these tools is NOT suitable for human participants?
a) fMRI
b) CAT
c) Optogenetics
d) EEG
c) Optogenetics
What tool washes away lipids, leaving only the cell membrane?
a) Immunohistochemistry staining
b) Chemogenetics
c) Microscopy
d) CLARITY
d) CLARITY
Which tool inserts channelrhodopsin into neurons, allowing them to be activated with a light?
a) Optogenetics
b) immunohistochemistry staining
c) chemogenetics
d) diffusion tensor imaging
a) Optogenetics
What tool can both measure and manipulate neurons?
a) CRISPR-Cas9
b) Electroencephalography
c) Microscopy
d) Electrophysiology
d) Electrophysiology
Which tool uses magnetic pulses to modulate brain activity?
a) functional magnetic resonance imaging
b) transcranial magnetic stimulation
c) diffusion tensor imaging
d) computerized tomography scan
b) transcranial magnetic stimulation