Self-Assessments & Knowledge Checks

Which of the following anti-helminthic drug is contradicted in pregnancy due to its possible embryocidal effect?

Albendazole

Which of the following life forms of Entamoeba histolytica is more resistant to anti-protozoal drugs?

Cyst

Which of the following is a pro-drug that is reduced to an active free radical that targets obligate anaerobes?

Metronidazole

Which of the following is a first-line treatment for both scabies and lice?

Permethrin

Which of the following anti-helminthic  kills schistosomes, cestodes and trematodes but NOT nematodes?

Praziquantel

What is the mechanism of action of Ivermectin?

It is a GABA agonist

Which of the following drugs can be used to substitute for sulfadiazine in a combination treatment for patients with sulfur sensitivity?

Clindamycin

A patient comes to the clinic looking malnourished and they present with abdominal pain, fever and general body weakness. A stool sample detects  the ova of both Necator americanus and Trichuris trichuria. Which of the following drugs would be effective in treating this mixed infection? 

Albendazole

Which of the following drugs works by inhibiting dihydrofolate reductase enzymes?

Drug C (bottom left)

Which of the following statements is true regarding the compound? Select 2 that apply

A) It is not used as a part of combination therapies

B) It is a tissue schizonticide

C) It can be used for the treatment of severe malaria

D) It kills plasmodium species via a free radical mechanism

C and D

Patients with glucose-6-phosphate dehydrogenase deficiency are at increased risk of hemolytic anemia when taking which of the following drugs? Select two that apply.

Drug C (bottom left) and Drug D (bottom right)

Which of the following compounds have activity against hypnozoites? select two that apply.

Drug B (top right) and Drug D (bottom right)

Which one of the following drugs is commonly used for malaria prophylaxis?

Drug B (top right)

Which of the following is true regarding the compound below?

A) For severe treatment of malaria

B) Blood schizonticide

C) Orally active

D) Kills plasmodium species via a free radical mechanism

B and C

Which of the following has both blood and tissue schizonticide activity?

Drug B (top right)