Ch. 18 Aromatic Substitution Reagents

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Last updated 7:00 PM on 10/1/26

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7 Terms

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Halogenation reagents

Al or FeX₃ + X₂

X = Br or Cl

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Sulfonation reagents

Fuming H₂SO₄

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Nitration reagents

HNO₃ + H₂SO₄

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Reduction of NO₂ to amine

use Fe or Zn, HCl

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Friedel-Crafts Alkylation

primary, secondary, or tertiary alkyl halide (Cl favored)

AlCl₃

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Friedel-Crafts Acylation

acyl halide (mostly Cl)

1) AlCl₃

_{2) H2O}

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Reducing acylation product

Zn (Hg), HCl, heat