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Cushing’s Disease Cause
Adrenal cortex produces excessive cortisol, could be due to tumor in pituitary gland increasing ACTH or tumor in adrenal gland
Cushing’s Disease Symptoms (MFMB)
Muscle weakness, fatigue, mood swings, and easy bruising
Cushing’s Disease Exam Signs (H WFBT HES)
Hypertension, increased body weight with fat deposits in the face (moon face), upper back (buffalo hump), and the trunk, hirsutism, edema, and skin discoloration
Cushing’s Disease Diagnosis
Test cortisol in the blood, determine cause, tumors may need surgical resection
Cushing’s Disease Complication
Osteoporosis
Diabetes Mellitus
Chronic disease with abnormal glucose metabolism
Diabetes Mellitus Cause
Hyposecretion of insulin or cells fails to respond to insulin
Subtypes of Diabetes Mellitus
IDDM and NIDDM
Insulin Dependent Diabetes Mellitus
Patients no longer produce insulin
Non-Insulin Dependent Diabetes Mellitus
Patients produce insulin, but the cells throughout the body do not respond to it
Diabetic Ketoacidosis
Body uses fat as main source of fuel instead of carbs
Diabetic Ketoacidosis Complications
Elevated blood glucose levels for extended periods may cause tissue damage
Diabetes Mellitus Complications
May develop hyperglycemia and hypoglycemia
Hypoglycemia Complications
Can lead to shock if not addressed promptly; can cause tissue damage after years of poor glucose control
Insulin Dependent Diabetes Mellitus Treatment
Insulin injections
Non-Insulin Dependent Diabetes Mellitus Treatment
Medications to increase cell sensitivity to insulin
Hyperthyroidism
Condition of excessive thyroid hormone secretion
Hyperthyroidism Causes (GT3)
Graves’ disease, toxic multinodular goiter, thyroiditis, and benign or malignant tumors
Graves’ Disease
Autoimmune disease where antibodies stimulate the thyroid to produce too much T4
Toxic Multinodular Goiter
enlargement of the thyroid that then produces too much thyroid hormone
Hyperthyroidism Symptoms (HNISPWDE ^BMR)
Hyperactivity, nervousness, irritability, sweating, palpitations, weight loss, diarrhea, and easy fatigue due to increased basal metabolic rate
Hyperthyroidism Treatment (MRS)
medications, radioiodine treatment (to destroy thyroid tissue), or surgical removal of part of the thyroid (partial thyroidectomy) to reduce the amount of thyroid hormone
Hypothyroidism
Deficiency of thyroid hormone
Hypothyroidism Causes (H,T,R,T,M)
Hashimoto’s thyroiditis, treatments for hyperthyroidism, radiation treatments, thyroid surgery, and certain medications
Hypothyroidism Symptoms (TWDCHWDvBMR)
Tired, weak, dry skin, feeling cold, hair loss, weight gain, and dyspnea due to decreased basal metabolic rate
Hypothyroidism Treatment
Supplementation with synthetic thyroid hormone