Sodium glucose cotransporter 2 inhibitors SGLT2Is for HF

0.0(0)
studied byStudied by 0 people
0.0(0)
full-widthCall with Kai
GameKnowt Play
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
Card Sorting

1/5

encourage image

There's no tags or description

Looks like no tags are added yet.

Study Analytics
Name
Mastery
Learn
Test
Matching
Spaced

No study sessions yet.

6 Terms

1
New cards

What were SGLT2Is introduced for?

type II diabetes, but have shown to decrease hospitalization and mortality in HF

2
New cards

What is the mechanism of the clinical effect?

likely independent of their glucose effects but actually unclear

3
New cards

What are the positive clinical effects of SGLT2Is?

  • significant reductions in HF worsening

  • significant reductions in CV mortality 

4
New cards

What SGLT2Is are licensed for use in HF in the UK?

dapagliflozin and empagliflozin 

5
New cards

Who are SGLT2Is indicated for?

all patients with reduced, mildly reduced or preserved EF

6
New cards

What are the possible adverse effects?

  • diabetic ketoacidosis

  • urogenital and soft tissue infections

  • hypoglycaemia