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Cerebrum
Largest brain region; supports conscious sensation, voluntary movement, thinking, language, and memory.
Longitudinal fissure
Deep groove separating the left and right cerebral hemispheres.
Insula
Cortical region hidden deep within lateral sulcus; involved in taste, balance awareness, and visceral sensation.
Gyrus (gyri)
Raised ridge or fold of the cerebral cortex.
Sulcus (sulci)
Groove in the cerebral cortex; along with gyri, increases cortical surface area.
Central sulcus
Groove separating the precentral motor gyrus from the postcentral sensory gyrus.
Lateral sulcus
Groove separating temporal lobe from overlying frontal and parietal regions.
Parieto-occipital sulcus
Groove marking boundary between parietal and occipital lobes, especially medially.
Gray matter
Neural tissue containing neuron cell bodies, dendrites, and unmyelinated axons.
Cerebral cortex
Superficial layer of gray matter in the cerebrum.
Nucleus (CNS)
Functional collection of neuron cell bodies deep within the brain.
White matter
Neural tissue mainly consisting of myelinated axons.
Tract
Bundle of axons traveling together in the central nervous system.
Projection tracts
White matter pathways connecting cerebrum with lower CNS regions, including spinal cord.
Commissural tracts
White matter pathways connecting left and right cerebral hemispheres.
Corpus callosum
Major commissural tract linking left and right cerebral hemispheres.
Association tracts
White matter pathways connecting regions within the same cerebral hemisphere.
Sensory cerebral areas
Areas responsible for conscious awareness of sensations.
Motor cerebral areas
Areas involved in voluntary motor control.
Association cortex
Cortical regions that integrate information from multiple areas; most of cortex.
Frontal lobe
Lobe involved in planning, behavioral regulation, and voluntary movement.
Prefrontal cortex
Large association cortex for planning, decision-making, self-awareness, and behavioral regulation; matures into roughly mid-20s.
Precentral gyrus
Site of primary motor cortex; controls voluntary movement.
Primary motor cortex
Cortical area on precentral gyrus sending commands for voluntary muscle movements.
Premotor cortex
Frontal cortical region for planning and coordinating movements.
Motor homunculus
Map of body parts across motor cortex; relative size reflects amount of cortex devoted to motor control.
Broca's area
Typically left frontal region for speech production, motor coordination of speech, and grammar.
Broca's aphasia
Impaired speech production with relatively preserved comprehension; speech is effortful and short, sometimes affects writing or signing.
Parietal lobe
Lobe involved in general sensation, attention, and spatial awareness.
Parietal association cortex
Supports spatial awareness and visual attention.
Postcentral gyrus
Site of primary somatosensory cortex for general body sensation.
Primary somatosensory cortex
Receives and consciously processes general body sensations.
Somatosensory association cortex
Integrates sensory inputs and supports tactile memory.
Sensory homunculus
Map of body parts in sensory cortex; size reflects cortical representation of sensation.
Temporal lobe
Lobe containing hearing and smell areas plus regions for recognition and language comprehension.
Primary auditory cortex
Cortical region receiving auditory information.
Olfactory cortex
Cortical region involved in perception of smell.
Auditory association cortex
Helps classify and interpret sounds.
Visual association cortex (temporal)
Helps recognize and interpret what is seen.
Wernicke's area
Usually left temporal region important for understanding spoken language and word meanings.
Wernicke's aphasia
Speech may be fluent but nonsensical; language comprehension, reading, and writing may be severely impaired.
Occipital lobe
Primary lobe for vision processing.
Primary visual cortex
Receives and processes visual input.
Visual association cortex (occipital)
Analyzes visual features such as color, shape, and orientation.
Vestibular cortex (insula)
Area associated with conscious awareness of balance.
Gustatory cortex (insula)
Area associated with conscious perception of taste.
Visceral sensory cortex (insula)
Area associated with internal organ sensations.
Basal nuclei
Deep cerebral gray matter structures helping initiate and regulate voluntary movement, habits, and procedural learning.
Caudate nucleus
One of the major components of the basal nuclei.
Putamen
One of the major components of the basal nuclei.
Globus pallidus
One of the major components of the basal nuclei.
Basal nuclei movement function
Support intended voluntary movements and inhibit unnecessary or antagonistic movements.
Basal nuclei nonmotor functions
Contribute to procedural learning, habitual behavior, and decision-making.
Limbic system
Network of brain regions involved in emotion and memory, including amygdala, hippocampus, and cingulate gyrus.
Cingulate gyrus
Limbic area involved in emotional expression.
Amygdala
Limbic structure strongly involved in fear responses.
Hippocampus
Limbic structure important for forming memories and spatial navigation.
Olfaction and limbic system
Smells can evoke emotional responses and memory formation or retrieval.
Memory
Encoding, storing, and retrieving information or experiences.
Declarative memory
Conscious recollection of facts and knowledge.
Nondeclarative memory
Unconscious memory expressed through skills and procedures.
Immediate memory
Information retained for just a few moments.
Short-term (working) memory
Limited information held temporarily, often for minutes.
Long-term memory
Information retained over long periods, potentially years.
Memory consolidation
Process stabilizing information into long-term memory; shaped by rehearsal, associations, and emotion.
Long-term potentiation (LTP)
Persistent increase in synaptic strength between associated neurons; supports memory formation.
Hippocampus in consolidation
Helps organize information into unified memories; supports LTP, dendrite growth, and transmitter release.
Long-term memory storage
Memory components can be stored in relevant cortical areas, such as sound-related details in auditory cortex.
Cognitive map
Mental representation of surroundings supporting spatial navigation; involves hippocampus.
London taxi driver study
Lecture example of increased hippocampal gray matter associated with extensive spatial navigation experience.
Diencephalon
Brain region including the thalamus, hypothalamus, and epithalamus.
Thalamus
Gatekeeper that filters, sorts, and relays signals to cerebral cortex.
Thalamus sensory role
Relays sensory information received from spinal cord and cranial nerves to cortex.
Thalamus motor role
Processes input from basal nuclei and cerebellum for regulation of motor cortex activity.
Thalamus emotional role
Processes input from limbic system and hypothalamus for emotional awareness and response.
Hypothalamus
Major homeostatic control center coordinating temperature, hunger, thirst, hormones, sleep, ANS, and emotion.
Homeostasis
Maintenance of relatively stable internal conditions.
Hypothalamic thermoregulation
Maintains body-temperature set point and helps initiate fever.
Hypothalamic food regulation
Monitors blood chemistry and hunger/fullness signals to regulate appetite and satiety.
Hypothalamic fluid regulation
Monitors blood osmolarity, causes thirst, and helps kidneys conserve water.
Osmolarity
Concentration of dissolved particles in a fluid; monitored for water balance.
Antidiuretic hormone (ADH)
Hormone produced by hypothalamus that helps kidneys conserve water.
Oxytocin
Hormone produced in hypothalamus and released by posterior pituitary.
Hypothalamus and pituitary
Hypothalamus regulates pituitary activity and influences endocrine function.
Circadian clock
Hypothalamic timing system coordinating daily rhythms of behavior and physiology.
Homeostatic sleep drive
Sleep pressure that grows as time spent awake increases.
Hypothalamus and ANS
Uses signals from organs, cortex, and limbic system to regulate autonomic centers in brainstem.
Hypothalamus and emotions
Links limbic activity to conscious emotional perception and bodily autonomic responses.
Epithalamus
Diencephalic region that includes pineal gland and participates in circadian timing.
Pineal gland
Releases melatonin on a circadian schedule to coordinate biological timing.
Melatonin
Hormone whose circadian secretion supports timing of sleep and other rhythms.
Emotion
Response involving interpretation of stimuli, bodily (autonomic and somatic) changes, and cognition.
Visceral motor emotional response
Autonomic bodily response such as racing heart or blushing.
Somatic motor emotional response
Skeletal-muscle response such as smiling or frowning.
Cognitive emotional response
Conscious recognition, expression, or regulation of emotion.
Circadian alerting system
Light signals from eyes to hypothalamus help promote alertness by day and sleep readiness at night.
Sleep onset
Hypothalamic actions reduce brainstem-thalamus communication and cortical responsiveness while brainstem functions continue.
NREM stage 1
Brief transition from wakefulness to sleep; lecture lists about 1-5 minutes.
NREM stage 2
Light sleep with reduced heart rate, breathing rate, blood pressure, body temperature, and stopped eye movements; about 10-60 minutes.
NREM stage 3
Deep sleep with muscle relaxation, reduced brain activity, tissue repair, and declarative-memory consolidation; about 20-40 minutes.