eosinophilic esophagitis

What type of immunoglobulin and what T cell

IgE and Th2

Diff between EoE and EGE

Diag by endoscopy

-Longitudinal furrows in lower esophageal mucosal surface btw long esophageal folds

-constrictions (ring)

-whit plaques

-multiple biopsies should be taken

Histo

For the diagnosis of eosinophilic esophagitis, eosinophil

infiltration >15 eosinophils/high-power field (HPF) in the

esophageal epithelial layer in at least 1 microscopic field

is necessarY

Treatments

3DS

-dietary modification (1st line treatment including elemental and elimination diets)

-drugs

. 1st try 8w PPI → if good → complete it and dont try 2nd option

. 2nd try 8-12w glucocorticoids

Fluticasone (spray into the mouth )

Budesonide (oral viscous solution)

-esophageal dilations