Compounding

Compounding

combining, mixing, or altering ingredients

Reconstituion

Adding a diluent to a dry ingredient to make it a liquid

Compounding legal Requirements

Must keep on hand formulation records compounding records, standard operating procedures and ingredient records.

Are the Compounding legal Requirements for compounded or reconstituded medications

Compounded Medications

What is the Formulation Record Sometimes called

Master Formulation Record

What is needed for the formulation record

• Name, strength, and dosage form

• Physical description ( color,texture) 

• Description of all ingredients and quantities

• Complete instructions including equipment, supplies, and sterilization method

When should you do the compounding Record

At the time of compounding

What is the Standard Operating Procedures short hand for

SOPs

Ingredient Record

Records all ingredients used in the pharmacy for compounding

Certificate of Analysis

Document issued by quality assurance stating that the product meets its specifications 

What is the MSDS referred to as

Material Safety Data Sheets

Material Safety Data Sheets

document that contains information on potential hazards and how to work safely with a chemical

What are the 5 steps for compounding wokflow

1. Preparation

2. Compounding

3. Final Check

4. Sign-off

5. Cleaning

Beaker

Least accurate, used to measure large quantities

Graduated Cylinder

Most accurate for mearing liquids

Reading liquids

Liquid volumes should be read at eye level and should be measured from the bottom of the curve

IV Pain Medications

Patient Controlled Analgesic

Patient Controlled Analgesic

PCA

IV Push

All of the medication in a syringe is given at one time 

Continuous Infusion

Medication is infused into a patient over a specified period of time

IV Piggyback

Medications that are delivered over top of the main line fluids

Total Parenteral Nutrition

Fluid comprised of proteins, fats, carbs, electrolytes, multivitamins, nutrients, etc 

Total Parenteral Nutrition Abbreviation

TPN

Trituration

Reducing a particle size by use of a mortar and pestle 

Levigation

Creation of a paste usually by trituration while wet

Spatulation

The mixing of solid materials by continuously heaping them together with a spatula until homogenous mixture is obtained

Horizontal Air flow hood

Non hazardous comounding blows air towards you

Vertical air flow hood

Used for Hazardous compounding. Air pushes top down so it goes into the hood to recycle the air

High Efficiency Particulate Air filter acronym

HEPA

What type of filter do the laminar flow hoods use

High Efficiency Particulate Air filter

When should you use a filter needle

When drawing liquid out of an ampule

What can be used for more than one dose?

Multiple dose vial

Multiple Dose Vial acronym

MDV

Single Dose Vial acronym

SDV

Ampule

A sealed glass container that must be broken open and is intended for single use only

Lactaed Ringers acronym

LR

Lactated Ringers

Replenishes body fluid and electrolytes

How should a vertical laminar flow hood be cleaned?

Starting in the back, wiping side to side and working forward towad the user

When working in a horizontal laminar flow hood, you should work a minimum of how many inches from inside of the front edge of the hood?

6 inches

Class A balances are used by most pharmacies. The minimum that can be weighed on them is?

120mg

Negative Pressure

air draws in when door is open

Positive Pressure

air blows out of the room when door is opened