PDDS211 Laboratory Exercise 6: Pastes and Creams

Comprehensive question-and-answer flashcards covering formulations, compounding steps, labeling, submission guidelines, and dosage form comparisons for PDDS211 Laboratory Exercise 6: Pastes and Creams.

According to the dosage form comparison table, what are the composition, appearance, and feel of an ointment?

Hydrocarbon based greasy semisolid; translucent to opaque; greasy.

According to the dosage form comparison table, what are the composition, appearance, and feel of a cream?

Mostly water-based where drugs are loaded in O/W or W/O emulsion; opaque; less greasy.

According to the dosage form comparison table, what are the composition, appearance, and feel of a paste?

Basically an ointment where a high percentage of insoluble solids are added; opaque; less greasy.

According to the dosage form comparison table, what are the composition, appearance, and feel of a gel?

The liquid phase is trapped within a three-dimensional polymeric matrix; transparent; non-greasy.

What are the ingredients and quantities in the $1000\,\text{g}$ master formula for Compounding Formula 6-A (Zinc Oxide Paste)?

Zinc oxide ($250\,\text{g}$), Starch ($250\,\text{g}$), and White petrolatum ($500\,\text{g}$).

What is the prescribed quantity to prepare (M. Et. Ft.) for Compounding Formula 6-A (Zinc Oxide Paste)?

$$10\,\text{grams}$$

What container is specified for packaging Compounding Formula 6-A (Zinc Oxide Paste)?

Collapsible Tube

What is the step-by-step compounding procedure for Compounding Formula 6-A (Zinc Oxide Paste)?

1. CALCULATE & WEIGH.
2. Triturate the zinc oxide and starch together until a fine, uniform blend is achieved.
3. Gradually incorporate the powder mixture into the white petrolatum.
4. Continue mixing until a smooth, uniform ointment is formed.

What are the ingredients and their quantities in the approximately $100\,\text{grams}$ master formula for Compounding Formula 6-B (Vanishing Cream)?

Stearic acid ($18\,\text{g}$), Glycerin ($3\,\text{g}$), Lanolin ($2\,\text{g}$), Triethanolamine ($1\,\text{g}$), Methyl paraben ($0.18\,\text{g}$), Propyl paraben ($0.02\,\text{g}$), Purified water ($75.8\,\text{ml}$), and Rose oil (q.s., OPTIONAL).

What is the prescribed quantity to prepare (M. Et. Ft.) for Compounding Formula 6-B (Vanishing Cream)?

$$10\,\text{grams}$$

What container is specified for packaging Compounding Formula 6-B (Vanishing Cream)?

Ointment Jar

At what temperature is lanolin melted during the preparation of Compounding Formula 6-B (Vanishing Cream)?

In a water bath at $60^\circ\text{C}$ (60deg Celsius).

In the compounding procedure for Vanishing Cream (6B), which ingredients are combined and heated in a separate beaker?

Glycerin, triethanolamine (TEA), and water.

When are the parabens and rose oil added during the preparation of Vanishing Cream (6B)?

After slowly adding the melted stearic acid–lanolin mixture into the heated glycerin–TEA–water mixture and allowing the mixture to cool slightly.

What are the patient name, Rx number, and physician's name for the label of Formula 6A (Zinc Oxide Paste)?

Patient name: Xander Grande; Rx no.: E06A-101026; Physician’s name: Dr. Agnes Calay.

What are the patient name, Rx number, and physician's name for the label of Formula 6B (Vanishing Cream)?

Patient name: Maximo Gallardo; Rx no.: E06B-101026; Physician’s name: Dr. Memo Reyes.

What format is required for the pharmacist's name on the label for Formula 6A versus Formula 6B?

For Formula 6A: STUDENT’S NAME (individual); For Formula 6B: GROUP NO. - SECTION (group).

What is the two-step cleaning procedure outlined for the laboratory session?

1. Wipe residue: Rub gently with a cloth or paper towel/tissue to lift the dissolved grease.
2. Wash with detergent: Clean the area with warm water and a mild dish soap or surfactant-based detergent to remove remaining oily film.

What tasks and quizzes are scheduled for Day 1 of Week 9 (October 13)?

Submission of Datasheet and post-activity questions for exp. 5 and 6; Quiz 5: Ex. 5A and 5B; Quiz 6: Ex. 6A and 6B.

What preparations and containers are scheduled for Day 2 of Week 9 (October 17)?

Ex. 8A: Calamine Lotion ($10\,\text{mL}$ Flip Cap bottle, rubric and label) and Ex. 8B: Camphor & Soap Liniment ($10\,\text{mL}$ Narrow-mouth Amber Bottle, soap [dried and granulated], 2 rubrics per student).