4. Anesthesia, Paralysis, and Muscle Relaxants

What is the memory key for anesthetics and ICU/procedural sedation drugs?

They are primarily IV hospital drugs used for anesthesia/sedation

What serious effects can propofol cause?

Profound hypotension and respiratory depression

Why is propofol handled with strict aseptic technique?

The lipid emulsion supports microbial growth

What does dexmedetomidine commonly cause?

Bradycardia and hypotension

What is the memory key for neuromuscular blockers?

Paralytics do not provide analgesia or amnesia and require ventilatory support

Do paralytics provide analgesia?

No

Do paralytics provide amnesia?

No

What support is required with paralytics?

Ventilatory support

What serious electrolyte problem can succinylcholine cause?

Severe hyperkalemia

What condition can succinylcholine trigger in susceptible patients?

Malignant hyperthermia

Can a paralyzed patient still be conscious?

Yes

When may a paralyzed patient still be conscious?

If sedation/analgesia is inadequate

What is the memory key for skeletal muscle relaxants?

Most cause sedation and dizziness

Which skeletal muscle relaxants are also used for spasticity?

Baclofen and tizanidine

What substances should not be stacked with skeletal muscle relaxants?

Alcohol, opioids, benzodiazepines, or other sedatives

Can abrupt baclofen withdrawal be severe?

Yes

What effects can occur with abrupt baclofen withdrawal?

Agitation, hallucinations, seizures, and hyperthermia