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Bacteria with cell walls
Gram positive or negative
Crystal violet stain test
Hans Gram
Gram positive : purple
Gram negative : pink
Hopanoids
The sterol in bacterias. They don’t have cholesterol at the membrane
Gram positive bacteria
Have thick peptidoglycan layer as cell wall
No outer membrane

Gram negative bacteria
Cell wall composed of thin peptidoglycan layer & outer membrane
Outer phospholipid membrabe
Lipopolysaccharides in plasma membrane

Periplasmic space
Space between the two membranes in gram negative bacteria
Peptidoglycan layer
Made of alternating chains of NAG & NAM
NAM / N-acetylmuramic acid
NAG + Lactic acid
B(1-4) links

Penicilin
Inhibits an enzyme that builds the bacterial cell wall
Produced by fungi
Discovered by Fleming
B-lactam ring gives it anti-biotic properties
Does not kill live mature bacteria
Bacteria lyse when they try to divide

Lysozome
Also discovered by Fleming
In tears, saliva, mucus, milk
Breaks B(1-4) links between NAG & NAM
Exterior of E.Coli
Lipopolysaccharides
Fimbriae
Flagella
May also form: Pili or capsules

Lipopolysaccharides
Protects the cell
Lipid A is an endotoxin that is released upon lysis, induces overactivation of immune system
Fimbriae
Tubular protein appendages
Shorter than flagella
Used by gram - and some gram + bacteria to attach to host cells
NOT used for locomotion
Pili
Long protein tubes (similar to fimbriae)
Attach to “mating partner” for transference of genetic material
Flagella
Uses H+ for power (proton-motive force), spins the flagellum
Used for locomotion

Bacterial capsule slime layer
Capsule (rigid) slime layer (semi rigid)
Polysaccharide layer that surrounds bacterial cells external to the cell wall
Provides protection & adhesion

Biofilm
Form due to adhesion provided by the bacterial slime layer
Molliculites
Lack a cell wall
Archaea
Have ether bonds instead of ester bonds
Bilayer covalently bonded
Some have an S-layer made from protein, some have pseudopeptidoglycans (B1-3 bonds instead of B1-4)