heme II: hematopoesis + bone marrow

what is the normal myeloid to erythroid (M:E) ratio in the bone marrow

2:1 to 4:1

a normal hemoglobin molecule is comprised of

four heme and four globin chains

normal mature B cells express

CD19 and CD20

as an RBC ages, all of the following are true EXCEPT

they become less prone to phagocytosis

in which developmental stage do RBCs begin forming hemoglobin in amounts large enough to be visualized on a wright-stained bone marrow aspirate smear

polychromatic normoblast

which of the following cells are of lymphoid lineage

plasma cell

eosinophils are increased in all of the following EXCEPT

viral infections

during the second trimester of fetal development, the primary site of blood cell production is the

liver

what growth factor is produced in the kidneys and is used to treat anemia associated with kidney disease

EPO

a bone marrow biopsy and aspiration procedure would provide valuable diagnostic information for all of these conditions EXCEPT

iron deficiency anemia

osteoclasts

break down and remove bone tissue

osteoblasts

build and form new bone