Module 2 practice quizes

The ability to differentiate between antigen receptors for foreign antigens and the animal's own antigen cell is referred to as:

Immunologic tolerance

Which cell type is responsible for the adaptive immune system?

lymphocytes

Which type of leukocyte is active in both innate and adaptive immunity?

Neutrophils

Which type of immunity allows the animal to gain resistance to disease by antibodies received from colostrum?

Passive immunity

Which is the most common circulating immunoglobulin?

IgG

A horse is presented to the clinic and the veterinarian is suspecting equine infectious anemia. What test should be performed to confirm this diagnosis?

cELISA

What occurs when using a Snap ELISA test to indicate a positive test for an antigen?

Color appears in more than the positive control dot

Which term refers to a test's ability to correctly identify all animals that are truly positive for a specific reaction procedure?

Sensitivity

Which immunoassay test is the best to use when testing bovine serum for brucellosis antibodies?

cELISA

Most immunoassays involve the use of whole blood as the sample (T/F)

False

A minor cross-match involves mixing which two materials?

Donor serum and recipient cells

If a blood Type B cat receives a blood transfusion with Type A blood, what would most likely result?

Severe reaction and death

The majority of cats in the United States have what blood type?

A

The card agglutination assay for blood typing requires a sample collected with:

EDTA (purple top)

What happens if an animal is given a mismatched transfusion?

Antibodies form against the RBC antigens from the transfused sample

What type of testing is used to diagnose allergies or allergens in the environment?

Intradermal

Which antibody molecules mediate allergies, especially environmental allergens?

IgE

A patient with an allergy or hypersensitivity reaction may develop hives, which are also known as:

Urticaria

Hives and angioedema are reactions triggered when what type of cell releases histamine-containing granules that trigger the inflammatory response?

Basophils

Which of the following is used as a negative control in allergy testing?

Saline

If an antibody titer shows a high titer result, what does this indicate?

A high concentration of antibodies is present in the sample

In the real-time polymerase chain reaction, which of the following statements must be true for a sample to be considered positive?

As the number of segments increase, the fluorescence increases

In which test is a sample added to a test slide that has been coated with fluorescent dye-conjugated antigens and then examined with a special microscope?

Direct fluorescent antibody testing

Which assay test is similar to the cELISA technique except that a radioisotope replaces the enzyme?

Radioimmunoassay

This DNA test method decreases the risk of contamination and is easier to run than the traditional method

Real-time polymerase chain reaction

An autoimmune response in which the body's antibodies attack its own tissues is referred as which of the following?

Hypersensitivity

Another name for a Type III hypersensitivity disorder would be which of the following?

Immune complex disease

A patient shows evidence of hypersensitivity and the immune system shows a lack of phagocytes. In which of the following disorders are these characteristics?

Combined immunodeficiency

Which immune system disease is characterized by uncontrolled proliferation of lymphocytes?

Lymphoma

An animal is diagnosed with immune-mediated hemolytic anemia. What type of hypersensitivity disorder is IMHA?

Type II