A: End-of-life technique selection should consider animal welfare, speed and reliability of unconsciousness and death, species and individual characteristics, restraint requirements, personnel skill and safety, intended animal use, legal requirements, equipment or drug availability, psychological effects on people, and handling or disposal of remains. 🔎 What this means: There is no single best technique in every circumstance. A technically effective method may be inappropriate if personnel cannot use it competently, if it creates excessive distress, or if it conflicts with safety, legal, food-use, diagnostic, or environmental needs.